Citrate salts


Citrate salts are a subcategory of pharmaceutical active pharmaceutical ingredients (APIs) widely used in the pharmaceutical industry. These salts are derived from citric acid, a natural compound found in citrus fruits. Citrate salts are commonly utilized in various medications due to their excellent solubility and stability characteristics.

One of the most prominent citrate salts is potassium citrate, which is widely prescribed for the treatment and prevention of kidney stones. It works by increasing urine pH, reducing the concentration of stone-forming minerals, and inhibiting stone formation. Potassium citrate is also used as a buffering agent in various oral pharmaceutical formulations.

Calcium citrate is another notable member of the citrate salt family. It is commonly used as a dietary supplement to enhance calcium intake, particularly for individuals with calcium deficiencies or those who have difficulty absorbing calcium from other sources. Calcium citrate offers better absorption in comparison to other calcium salts, making it a popular choice for supplementation.

Sodium citrate, yet another citrate salt, is frequently employed as an anticoagulant during blood transfusions and hemodialysis procedures. It prevents clotting by binding to calcium ions in the blood, thereby inhibiting coagulation pathways.

Overall, citrate salts play a vital role in the pharmaceutical industry, offering a range of therapeutic benefits. Their versatility, solubility, and stability make them valuable components in various medications, dietary supplements, and medical procedures.

NameCAS number
Monosodium citrate18996-35-5
Trisodium citrate dihydrate6132-04-3