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Here is a short description about Dutasteride. Dutasteride is an oral synthetic 4-azasteroid commonly marketed under the trade name Avodart. It is a novel dual 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and irreversible manner. Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary hormonal mediator that plays a role in the development and enlargement of the prostate gland.
Dutasteride was approved by the FDA in 2001 for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men as monotherapy or in combination with the α-adrenergic antagonist tamsulosin to enhance the therapeutic response. Its clinical efficacy against benign prostate hyperplasia in male patients is comparable to that of finasteride, a specific type II 5α-reductase inhibitor. However, unlike finasteride, dutasteride is not yet indicated for the treatment of androgenic alopecia although it was demonstrated to be effective in several randomized, double-blind, placebo-controlled trials in androgenetic alopecia.
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Dutasteride manufacturers | traders | suppliers
We have 16 companies offering Dutasteride from 4 different countries.
Get in contact with the supplier of your choice:
- MSN Labs. from India
- Shandong Octagon Chemicals Limited from China
- TIEFENBACHER API + Ingredients from Germany
- Hunan Yuxin Pharmaceutical from China
- omicron pharma from India
- Ind-Swift Labs. from India
- Aurobindo from India
- Dr. Reddy's from India
- Swati Spentose from India
- Hetero Labs from India
- Glaxosmithkline from United Kingdom
- Cipla from India
- Sterling from Italy
- Hubei Gedian Humanwell from China
- HuNan Kerey from China
- Aquatic Remedies Pvt Ltd from India
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