Caldaret API Manufacturers
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Looking for Caldaret API 133804-44-1?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Caldaret. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Caldaret
- Synonyms:
- Cas Number:
- 133804-44-1
- DrugBank number:
- DB06231
- Unique Ingredient Identifier:
- 9L3Y3IJ2HI
General Description:
Caldaret is a chemical compound identified by the CAS number 133804-44-1. It is known for its distinct pharmacological properties and applications.
Indications:
This drug is primarily indicated for: Investigated for use/treatment in heart disease and myocardial infarction. Its use in specific medical scenarios underscores its importance in the therapeutic landscape.
Mechanism of Action:
Caldaret functions by: Cardiac damage due to the buildup of sodium (Na+) ischemia and early reperfusion leads to increased calcium (Ca2+) through the reverse mode Na+/Ca2+(NCX) ion exchanger. Caldaret is an intracardiac calcium (Ca2+) handling modulator whose cardioprotective actions are presumed to be due to inhibition of the NCX exhanger and increasing the uptake of Ca2+ via the sarcoplasmic reticulum (SR). This mechanism highlights the drug's role in inhibiting or promoting specific biological pathways, contributing to its therapeutic effects.
Classification:
Caldaret belongs to the class of organic compounds known as phenylpiperazines. These are compounds containing a phenylpiperazine skeleton, which consists of a piperazine bound to a phenyl group, classified under the direct parent group Phenylpiperazines. This compound is a part of the Organic compounds, falling under the Organoheterocyclic compounds superclass, and categorized within the Diazinanes class, specifically within the Piperazines subclass.
Categories:
Caldaret is categorized under the following therapeutic classes: Arylsulfonates, Arylsulfonic Acids, Benzene Derivatives, Sulfonic Acids, Sulfur Acids, Sulfur Compounds. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Caldaret is a type of Emollients and protectives
Emollients and protectives are an essential category of pharmaceutical Active Pharmaceutical Ingredients (APIs) used in various topical formulations. These substances play a crucial role in protecting and moisturizing the skin, making them widely utilized in the pharmaceutical and cosmetic industries.
Emollients are substances that help restore and maintain the skin's natural moisture barrier, preventing water loss and promoting hydration. They act by forming a thin film on the skin's surface, reducing transepidermal water loss (TEWL) and improving the skin's texture and elasticity. Common emollients include natural oils, such as jojoba oil, almond oil, and shea butter, as well as synthetic compounds like mineral oil and petrolatum.
Protectives, on the other hand, are API ingredients that shield the skin from harmful external factors, such as irritants, allergens, and environmental pollutants. They create a physical barrier that prevents the penetration of harmful substances into the skin. Protectives are often combined with emollients to provide a dual function of hydration and protection.
The applications of emollients and protectives are vast and encompass a wide range of pharmaceutical and cosmetic products. They are commonly found in moisturizers, creams, lotions, ointments, balms, and sunscreens. These APIs are especially beneficial for individuals with dry or sensitive skin, as they can soothe irritation, reduce redness, and alleviate discomfort.
In conclusion, emollients and protectives are vital categories of pharmaceutical APIs that provide hydration and protection to the skin. Their versatile applications make them crucial ingredients in a wide array of topical formulations, contributing to the overall health and well-being of the skin.
