Dihydrexidine API Manufacturers

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Looking for Dihydrexidine API 123039-93-0?

Description:
Here you will find a list of producers, manufacturers and distributors of Dihydrexidine. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Dihydrexidine 
Synonyms:
 
Cas Number:
123039-93-0 
DrugBank number:
DB12890 
Unique Ingredient Identifier:
32D64VH037

General Description:

Dihydrexidine, identified by CAS number 123039-93-0, is a notable compound with significant therapeutic applications. Dihydrexidine has been used in trials studying the treatment of SPD, Cocaine-Related Disorders, and Schizotypal Personality Disorder.

Classification:

Dihydrexidine belongs to the class of organic compounds known as phenanthridines and derivatives. These are polycyclic compounds containing a phenanthridine moiety, which is a tricyclic system with two benzene rings joined by a pyridine forming a non-linear skeleton. Hydrogenated derivatives are also included, classified under the direct parent group Phenanthridines and derivatives. This compound is a part of the Organic compounds, falling under the Organoheterocyclic compounds superclass, and categorized within the Quinolines and derivatives class, specifically within the Benzoquinolines subclass.

Categories:

Dihydrexidine is categorized under the following therapeutic classes: Dopamine Agents, Dopamine Agonists, Heterocyclic Compounds, Fused-Ring, Neurotransmitter Agents, Nonergot-derivative Dopamine Receptor Agonists. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.

Dihydrexidine is a type of Ergot alkaloids


Ergot alkaloids are a prominent category of pharmaceutical Active Pharmaceutical Ingredients (APIs) that possess diverse medicinal properties. Derived from the fungus Claviceps purpurea, ergot alkaloids have been utilized for centuries in various therapeutic applications. These bioactive compounds exhibit vasoconstrictive, analgesic, and dopaminergic activities, making them valuable in the treatment of multiple medical conditions.

The primary medicinal use of ergot alkaloids lies in their efficacy in migraine management. Ergotamine and dihydroergotamine, two notable members of this category, are potent vasoconstrictors that alleviate migraine symptoms by narrowing blood vessels in the brain. These compounds also possess serotonin receptor agonist activity, further contributing to their therapeutic effect.

Furthermore, ergot alkaloids find application in obstetrics and gynecology. Ergometrine (ergonovine) and methylergometrine (methylergonovine) are commonly used to prevent and treat postpartum hemorrhage by promoting uterine contractions. Their ability to stimulate smooth muscle contraction makes them valuable in other gynecological procedures as well.

Despite their advantageous properties, ergot alkaloids require careful administration due to their potential side effects, including peripheral vasoconstriction and central nervous system disturbances. It is crucial for healthcare professionals to monitor dosage and usage to minimize adverse reactions.

In summary, ergot alkaloids represent a significant pharmaceutical API category with diverse applications in migraine management and obstetrics. Their potent bioactivity and historical significance contribute to their continued relevance in modern medicine.