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Trypsin
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Looking for Trypsin API 9002-07-7?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Trypsin. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Trypsin
- Synonyms:
- Tripsina , Trypsin
- Cas Number:
- 9002-07-7
- DrugBank number:
- DB11237
- Unique Ingredient Identifier:
- GV54A213NN
General Description:
Trypsin, identified by CAS number 9002-07-7, is a notable compound with significant therapeutic applications. Trypsin is a serine protease that plays an essential role in protein hydrolysis and absorption in mammals. When converted from its zymogen trypsinogen, trypsin is available as an active peptide hydrolase (EC 3.4.21.4) form to cleave peptide chains, mainly at the carboxyl side of the amino acids lysine or arginine. Trypsin contains a nucleophilic residue Ser in the enzyme active site which attacks the carbonyl moiety of the substrate peptide bond to form an acyl-enzyme intermediate . This nucleophilic attack is facilitated by the catalytic triad consisting of histidine-57, aspartate-102, and serine-195. Trypsin also contains an oxyanion hole that stabilizes the charge negative charge on the carbonyl oxygen atom formed from the cleavage of peptide bonds. Therapeutic forms of trypsin is obtained from purified extracts of porcine or bovine pancreas and is intended to aid in digestion when administered orally.
Categories:
Trypsin is categorized under the following therapeutic classes: Blood and Blood Forming Organs, Dermatologicals, Endopeptidases, Enzymes, Enzymes and Coenzymes, Hydrolases, Musculo-Skeletal System, Peptide Hydrolases, Preparations for Treatment of Wounds and Ulcers, Serine Endopeptidases, Serine Proteases. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Trypsin is a type of Hematological Agents
Hematological agents, belonging to the pharmaceutical API category, are a vital class of drugs used in the treatment of various blood disorders and hematological conditions. These agents play a crucial role in managing diseases related to the blood and its components, such as red blood cells, white blood cells, platelets, and plasma.
One significant application of hematological agents is in the treatment of anemia, a condition characterized by a low red blood cell count or hemoglobin level. Hematopoietic growth factors, a subclass of hematological agents, stimulate the production of red blood cells and enhance their maturation, thereby addressing anemia.
Another area where hematological agents demonstrate their therapeutic potential is in the treatment of blood cancers, such as leukemia, lymphoma, and multiple myeloma. These agents, including chemotherapy drugs and targeted therapies, help suppress the abnormal growth of cancer cells and restore normal blood cell production.
Hematological agents also find application in managing bleeding disorders, such as hemophilia and thrombocytopenia. They work by promoting blood clotting and preventing excessive bleeding. Additionally, certain hematological agents function as immunosuppressants, playing a crucial role in hematopoietic stem cell transplantation and preventing graft-versus-host disease.
Overall, hematological agents form a vital category within the pharmaceutical API domain, offering targeted treatments for a range of blood disorders and playing a significant role in improving the quality of life for patients with hematological conditions.
