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Fluasterone
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Looking for Fluasterone API 112859-71-9?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Fluasterone. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Fluasterone
- Synonyms:
- Cas Number:
- 112859-71-9
- DrugBank number:
- DB06250
- Unique Ingredient Identifier:
- R7M5UGD04G
General Description:
Fluasterone, identified by CAS number 112859-71-9, is a notable compound with significant therapeutic applications. Has antiproliferative effects on HIV-1 and reduces HIV-1 replication.
Indications:
This drug is primarily indicated for: Investigated for use/treatment in psoriasis and psoriatic disorders, hyperlipidemia, metabolic disease, cancer/tumors (unspecified), and obesity. Its use in specific medical scenarios underscores its importance in the therapeutic landscape.
Mechanism of Action:
Fluasterone functions by: Fluasterone is a synthetically stable adrenocortical steroid fluorinated analogue of dehydroepiandrosterone (DHEA), a powerful anti-inflammatory molecule with androgenic or estrogenic side effects. It is proposed that fluasterone inhibits NF-kB activation and reduces oxidative stress, but other mechanisms may play a role. Fluasterone suppresses inflammation and is effective in preclinical models of chronic inflammatory disease including psoriasis, asthma, rheumatoid arthritis, multiple sclerosis and lupus erythematosus. Fluasterone has anti-inflammatory effects inpreclinical models of chronic inflammatory disease including psoriasis, asthma, rheumatoid arthritis, multiple sclerosis and lupus erythematosus. This mechanism highlights the drug's role in inhibiting or promoting specific biological pathways, contributing to its therapeutic effects.
Classification:
Fluasterone belongs to the class of organic compounds known as androstane steroids. These are steroids with a structure based on the 19-carbon androstane skeleton, classified under the direct parent group Androstane steroids. This compound is a part of the Organic compounds, falling under the Lipids and lipid-like molecules superclass, and categorized within the Steroids and steroid derivatives class, specifically within the Androstane steroids subclass.
Categories:
Fluasterone is categorized under the following therapeutic classes: 17-Ketosteroids, Adrenal Cortex Hormones, Androstanes, Androstenes, Androstenols, Fused-Ring Compounds, Gonadal Hormones, Gonadal Steroid Hormones, Hormones, Hormones, Hormone Substitutes, and Hormone Antagonists, Ketosteroids, Steroids, Testosterone Congeners. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Fluasterone is a type of Hormones
Hormones are a vital category of pharmaceutical Active Pharmaceutical Ingredients (APIs) that play a crucial role in regulating various physiological processes in the human body. These chemical messengers are produced by endocrine glands and are responsible for maintaining homeostasis, growth, metabolism, and reproductive functions.
Pharmaceutical hormones are synthetic or naturally derived compounds that mimic the structure and function of endogenous hormones. They are widely used in the treatment of hormonal disorders, such as hypothyroidism, diabetes, and hormonal imbalances.
Common examples of hormone APIs include insulin, thyroid hormones (such as levothyroxine), glucocorticoids (such as prednisone), and sex hormones (such as estrogen and testosterone). These APIs are carefully synthesized, purified, and formulated to ensure optimal efficacy, stability, and bioavailability.
Hormone APIs are typically produced through advanced chemical synthesis or biotechnological processes, involving the use of genetically engineered microorganisms or mammalian cell cultures. Stringent quality control measures and regulatory guidelines ensure the purity, potency, and safety of hormone APIs.
Pharmaceutical companies and research institutions invest significant resources in developing hormone APIs, as they are fundamental for the treatment of various endocrine disorders. The demand for hormone APIs continues to grow, driven by the rising prevalence of hormonal diseases and an aging population.
In conclusion, hormone APIs are essential components of pharmaceuticals that help restore hormonal balance and alleviate various endocrine disorders. Their significance in healthcare makes them a crucial category in the pharmaceutical industry.
