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Trestolone
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Looking for Trestolone API 3764-87-2?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Trestolone. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Trestolone
- Synonyms:
- 17beta-Hydroxy-7alpha-methylestr-4-en-3-one , 17beta-Hydroxy-7alpha-methylestr-4-enone , 19-Nor-7alpha-methyltestosterone , 19-Nor-methyltestosterone , 7alpha-Methyl-17beta-hydroxy-4-estren-3-one , 7alpha-Methyl-19-nortestosterone , 7alpha-Methyl-3-oxo-4-estren-17beta-ol , 7alpha-Methylnandrolone , 7α-methyl-19-nortestosterone , MENT , Trestolona , Trestolonum
- Cas Number:
- 3764-87-2
- DrugBank number:
- DB05830
- Unique Ingredient Identifier:
- 40P3287I94
General Description:
Trestolone, identified by CAS number 3764-87-2, is a notable compound with significant therapeutic applications. Trestolone (7α-methyl-19-nortestosterone) is a synthetic androgen developed by the Population Council as a potential candidate drug for use in hormonal male contraceptive methods. In males, regular administration of sufficient quantities of trestolone induces a state of temporary infertility.
Indications:
This drug is primarily indicated for: Investigated for use/treatment in contraception and male hormonal deficiencies/abnormalities. Its use in specific medical scenarios underscores its importance in the therapeutic landscape.
Mechanism of Action:
Trestolone functions by: Trestolone is a potent inhibitor of the release of the luteinizing hormone (LH) and follicle stimulating hormone (FSH). As spermatogenesis requires both testosterone and FSH, it is impaired by the reduction in FSH caused by trestolone as well as the reduction in LH, and subsequent reduction in testosterone. This mechanism highlights the drug's role in inhibiting or promoting specific biological pathways, contributing to its therapeutic effects.
Categories:
Trestolone is categorized under the following therapeutic classes: Adrenal Cortex Hormones, Contraceptive Agents, Hormonal, Contraceptive Agents, Male, Estranes, Estrenes, Fused-Ring Compounds, Gonadal Hormones, Gonadal Steroid Hormones, Hormonal Contraceptives for Systemic Use, Hormones, Hormones, Hormone Substitutes, and Hormone Antagonists, Reproductive Control Agents, Steroids, Testosterone Congeners. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Trestolone is a type of Hormones
Hormones are a vital category of pharmaceutical Active Pharmaceutical Ingredients (APIs) that play a crucial role in regulating various physiological processes in the human body. These chemical messengers are produced by endocrine glands and are responsible for maintaining homeostasis, growth, metabolism, and reproductive functions.
Pharmaceutical hormones are synthetic or naturally derived compounds that mimic the structure and function of endogenous hormones. They are widely used in the treatment of hormonal disorders, such as hypothyroidism, diabetes, and hormonal imbalances.
Common examples of hormone APIs include insulin, thyroid hormones (such as levothyroxine), glucocorticoids (such as prednisone), and sex hormones (such as estrogen and testosterone). These APIs are carefully synthesized, purified, and formulated to ensure optimal efficacy, stability, and bioavailability.
Hormone APIs are typically produced through advanced chemical synthesis or biotechnological processes, involving the use of genetically engineered microorganisms or mammalian cell cultures. Stringent quality control measures and regulatory guidelines ensure the purity, potency, and safety of hormone APIs.
Pharmaceutical companies and research institutions invest significant resources in developing hormone APIs, as they are fundamental for the treatment of various endocrine disorders. The demand for hormone APIs continues to grow, driven by the rising prevalence of hormonal diseases and an aging population.
In conclusion, hormone APIs are essential components of pharmaceuticals that help restore hormonal balance and alleviate various endocrine disorders. Their significance in healthcare makes them a crucial category in the pharmaceutical industry.
