Idursulfase API Manufacturers
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Looking for Idursulfase API 50936-59-9?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Idursulfase. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Idursulfase
- Synonyms:
- Iduronate 2-sulfatase
- Cas Number:
- 50936-59-9
- DrugBank number:
- DB01271
- Unique Ingredient Identifier:
- 5W8JGG2651
About Idursulfase
It's time for some technical information for the ones who understand chemistry: Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. Idursulfase is produced by recombinant DNA technology in a human cell line. Idursulfase is an enzyme that hydrolyzes the 2-sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and heparan sulfate in the lysosomes of various cell types. Idursulfase is a 525-amino acid glycoprotein with a molecular weight of approximately 76 kilodaltons.
The enzyme contains eight asparagine-linked glycosylation sites occupied by complex oligosaccharide structures. The enzyme activity of idursulfase is dependent on the post-translational modification of a specific cysteine to formylglycine.
You can find more info about this product by clicking on the DB ID above.
