Imipenem API Manufacturers & Suppliers
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Established in: 2011
MOQ: 1 g
Employees: 10+
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Established in: 1997
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Looking for Imipenem API 74431-23-5?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Imipenem. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Imipenem
- Synonyms:
- Imipemide , Imipenem , Imipenem anhydrous , Imipenemum , IMP , N-formimidoylthienamycin
- Cas Number:
- 74431-23-5
- DrugBank number:
- DB01598
- Unique Ingredient Identifier:
- 71OTZ9ZE0A
About Imipenem
So, what does it do? Imipenem is a semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to many beta-lactamases. Similar compounds include meropenem, known for having greater activity against Gram negative bacteria, and the newer ertapenem which exhibits a longer half-life due to increased binding to plasma proteins. Imipenem is commonly used in combination with cilastatin and is now available in a triple-drug product with cilastatin and relebactam which was recently approved by the FDA.
Imipenem was first approved by the FDA in November 1985 as the combination product Primaxin marketed by Merck & Co.
Check who is selling Imipenem in the overview above.
Imipenem is a type of Carbapenems
Carbapenems are a subcategory of pharmaceutical Active Pharmaceutical Ingredients (APIs) widely used in the field of medicine. These powerful antibiotics are highly effective against a broad spectrum of bacteria, including multidrug-resistant strains. Carbapenems exhibit a unique molecular structure that makes them resistant to enzymatic degradation by most β-lactamases, enzymes produced by bacteria to break down β-lactam antibiotics.
Carbapenems work by inhibiting bacterial cell wall synthesis, leading to cell lysis and ultimately killing the bacteria. They are administered intravenously or intramuscularly and are often reserved for serious infections caused by bacteria resistant to other antibiotics.
Some commonly used carbapenems include imipenem, meropenem, and doripenem. These drugs are prescribed in hospitals for the treatment of severe infections such as complicated urinary tract infections, intra-abdominal infections, and pneumonia.
It is important to note that the use of carbapenems should be carefully monitored due to the emergence of carbapenem-resistant bacteria. The overuse or misuse of these antibiotics can contribute to the development of drug-resistant strains, posing a significant challenge in healthcare settings.
In conclusion, carbapenems are a vital subcategory of pharmaceutical APIs used to combat bacterial infections. Their unique molecular structure and broad-spectrum activity make them effective against various drug-resistant bacteria. However, responsible use and surveillance are crucial to prevent the emergence of resistant strains and ensure the continued efficacy of these important antibiotics.
Imipenem (Carbapenems), classified under Antibacterials
Antibacterials, a category of pharmaceutical active pharmaceutical ingredients (APIs), play a crucial role in combating bacterial infections. These APIs are chemical compounds that target and inhibit the growth or kill bacteria, helping to eliminate harmful bacterial pathogens from the body.
Antibacterials are essential for the treatment of various bacterial infections, including respiratory tract infections, urinary tract infections, skin and soft tissue infections, and more. They are commonly prescribed by healthcare professionals to combat both mild and severe bacterial infections.
Within the category of antibacterials, there are different classes and subclasses of APIs, each with distinct mechanisms of action and target bacteria. Some commonly used antibacterials include penicillins, cephalosporins, tetracyclines, macrolides, and fluoroquinolones. These APIs work by interfering with various aspects of bacterial cellular processes, such as cell wall synthesis, protein synthesis, DNA replication, or enzyme activity.
The development and production of antibacterial APIs require stringent quality control measures to ensure their safety, efficacy, and purity. Pharmaceutical manufacturers must adhere to Good Manufacturing Practices (GMP) and follow rigorous testing protocols to guarantee the quality and consistency of these APIs.
As bacterial resistance to antibiotics continues to be a significant concern, ongoing research and development efforts aim to discover and develop new antibacterial APIs. The evolution of antibacterials plays a crucial role in combating emerging bacterial strains and ensuring effective treatment options for infectious diseases.
In summary, antibacterials are a vital category of pharmaceutical APIs used to treat bacterial infections. They are designed to inhibit or kill bacteria, and their development requires strict adherence to quality control standards. By continually advancing research in this field, scientists and pharmaceutical companies can contribute to the ongoing battle against bacterial infections.
Imipenem manufacturers | traders | suppliers
We have 6 companies offering Imipenem produced in 2 different countries.
Get in contact with the supplier of your choice:
- Shandong Octagon Chemicals Limited from China, product country of origin China
- AXXO GmbH from Germany, product country of origin World
- Zhuhai United Labs from China, product country of origin China
- JW Pharmaceutical from South Korea, product country of origin South Korea
- Socosur from France, product country of origin Unknown
- Sun Pharma from India, product country of origin India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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