Intermediates


Pharmaceutical intermediates are a crucial category within the API (Active Pharmaceutical Ingredient) industry. These chemical compounds play a vital role in the synthesis of APIs, serving as building blocks or precursor molecules in the manufacturing process. Pharmaceutical intermediates are designed to undergo specific chemical transformations, enabling the production of targeted APIs with desired properties.

These intermediates are typically produced through complex organic synthesis, involving various chemical reactions and purification steps. They are carefully developed and optimized to ensure high purity, stability, and safety, meeting stringent regulatory requirements for pharmaceutical use.

Pharmaceutical intermediates offer several advantages in API production. Firstly, they enable the efficient and cost-effective synthesis of APIs by providing a well-defined starting material. This reduces the need for expensive or hard-to-obtain raw materials, streamlining the overall manufacturing process. Secondly, intermediates allow for fine-tuning of the chemical reactions, optimizing the yield and quality of the final API. This control over the synthesis process enhances the consistency and reproducibility of pharmaceutical manufacturing.

Moreover, pharmaceutical intermediates facilitate the development of new APIs and drug formulations. By modifying the structure or functional groups of the intermediate molecules, researchers can explore different chemical pathways and create novel compounds with improved therapeutic efficacy, reduced side effects, or enhanced bioavailability.

In summary, pharmaceutical intermediates are essential components in API synthesis, enabling efficient and controlled production of pharmaceutical compounds. Their versatility and role in driving innovation make them indispensable in the pharmaceutical industry.

NameCAS numberCategoryAmount of suppliers
"(S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methyl Sulfonyl)Ethylamine N-Acetyl-L-Leucine Salt"608141-43-1Intermediates1
((1R,4R)-4-(Methyl(7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methyl methanesulfonateNAIntermediates1
((1R,4R)-4-(Methylamino) cyclohexyl)methanol ((1R,4R)-4-(Methylamino) cyclohexyl)methanol 400898-77-3Intermediates1
(1-(3-(Trifluoromethyl)-5,6-dihydro- [1,2,4] triazolo [4,3-a] pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl) butane-1,3-dione)764667-64-4Intermediates1
(1-Methyl-1H-1,2,4- Triazole -3-Yl)Methanol135242-93-2Intermediates1
(2R,3R,4R,5S,6S)-2-(Acetoxymethyl)-6-(4-Chloro-3-(4-Ethoxybenzyl)Phenyl) Tetrahydro-2H-Pyran-3,4,5-Triyl Triacetate461432-25-7Intermediates1
(2S,5R)-5-((Benzyloxy)amino) piperidine-2-carboxamide 1416134-49-0Intermediates1
(2S,5R)-6-(Benzyloxy)-7-oxo- 1,6-diazabicyclo [3.2.1] octane-2-carboxamide1192651-49-2Intermediates1
(3,4-Dimethoxyphenyl)Acetonitrile93-17-4Intermediates1
(3R,4S,5R,6R)-3,4,5-Tris((Trimethylsilyl)Oxy)-6- (((Trimethylsilyl)Oxy)Methyl)Tetrahydro-2H-Pyran-2-One32384-65-9Intermediates1
(4-Chlorobutyl)Benzene 4830-93-7Intermediates1
(4R)-4-Propyloxolan-2-One63095-51-2Intermediates1
(4R,6S)-4-Hydroxy-6-Methyl-5,6-Dihydro-4H-Thieno[2,3-B]Thiopyran-7,7-Dioxide (Chiral Sulfone)147128-77-6Intermediates1
(Dimethyl Carbamoyl) Methyl-2-(4-Hydroxyphenyl) Acetate59721-16-3Intermediates1
(R)-(+)-1-(Napthyl)Ethyl Amine3886-70-2Intermediates1
(R)-5-(2-Aminopropyl)-2- Methoxybenzenesulfonamide112101-81-2Intermediates1
(S)-(+)-3-Hydroxy-Tetrahydrofuran86087-23-2Intermediates1
(S)-1-(3-Ethoxy-4-Methoxyphenyl)-2- (Methylsulfonyl)Ethanamine608141-42-0Intermediates1
(S)-3-(4-(2-chloro-5-iodobenzyl) phenoxy) tetrahydrofuran915095-94-2Intermediates1
(S)-3-(4-(5-Bromo-2-Chlorobenzyl)Phenoxy)Tetrahydrofuran915095-89-5Intermediates1
(S)-Ethyl-5-(Pentan-3-Yloxy)-7-Oxabicyclo[4.1.0]Hepta-3,5- Diene-3-Carboxylate [Epoxide]204254-96-6Intermediates1
1,1-Dimethylethyl 4-(Cyclopropylcarbonyl)-1-Piperazinecarboxylate414910-15-9Intermediates1
1,2-Benzisoxazole-3-Methanesulfonate Sodium Salt73101-64-1Intermediates1
1-(2-Amino-1-(4-Methoxyphenyl)Ethyl) Cyclohexanol Hydrochloride - Venamine Hcl130198-05-9Intermediates1
1-(2-Chloroethoxy)-2-Ethoxybenzene56842-04-7Intermediates1
1-(2-Chloroethoxy)-2-Methoxybenzene53815-60-4Intermediates1
1-(2-Ethoxyethyl)-2-(Piperidin-4-Yl)-1H-Benzo[D]Imidazole Hcl1841081-72-8Intermediates1
1-(3-Chloro Phenyl)-4-(3-Chloro Propyl) Piperazine Hcl52605-52-4Intermediates1
1-(3-Chloro Phenyl)-4-(3-Chloro Propyl) Piperazine Hcl52605-52-4Intermediates0
1-(3-Chlorophenyl)Piperazine Hydrochloride65369-76-8Intermediates1
1-(3-Ethoxy-4-Methoxyphenyl)-2- (Methylsulfonyl)Ethanamine253168-94-4Intermediates1
1-(4-Fluorophenyl)-5-(2-Oxo-4-Phenyloxazolidin-3-Yl)Pentane-1,5-Dione189028-93-1Intermediates1
1-(Difluoromethyl)-4-Nitro-1H-Pyrazole956477-64-8Intermediates1
1-(Ethylsulfonyl)-3-[4-[7-[[2-(Trimethylsilyl)Ethoxy]Methyl]-7H-Pyrrolo[2,3-D]Pyrimidine1187594-13-3Intermediates1
1-Azaphenothiazine261-96-1Intermediates1
1-Boc-5-Amino-1H-Indazole129488-10-4Intermediates1
1H-Pyrazole-1-Propanenitrile, Β-Cyclopentyl-4-[7-[[2-(Trimethylsilyl)Ethoxy]Methyl]-7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl]- 941685-39-8Intermediates1
1H-Pyrazole-1-Propanenitrile, Β-Cyclopentyl-4-[7-[[2-(Trimethylsilyl)Ethoxy]Methyl]-7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl]- (Racemic)941688-05-7Intermediates1
2, 6-Dihydroxy Acetophenone699-83-2Intermediates1
2,2,14,14-tetramethyl-8-oxopentadecanedioic acid413624-71-2Intermediates1
2,2,6,6-Tetramethylpiperidine768-66-1Intermediates1
2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone32384-65-9Intermediates1
2,3-Diaminopyridine452-58-4Intermediates1
2,6-Difluorobenzyl Bromide85118-00-9Intermediates1
2,6-Difluorobenzyl Chloride697-73-4Intermediates1
2-(1-Piperazinyl)Pyrimidine20980-22-7Intermediates1
2-(2,2,2-Trifluoroacetamido) acetic acid383-70-0Intermediates1
2-(2- Aminophenylamino)-5-Methylthiophene-3- Carbonitrile138564-60-0Intermediates1
2-(2-(4-Bromophenyl) Propan-2-Yl)-4,4-Dimethyl-4,5-Dihydrooxazole192775-97-6Intermediates1
2-(3,4-Dimethoxyphenyl) (Isovetryl Cyanide) (Ivc)20850-49-1Intermediates1
2-(3,4-Dimethoxyphenyl)-N-Methylethanamine (Nmva)3490-06-0Intermediates1
2-(4-Bromophenyl)-2-Methylpropanoic Acid32454-35-6Intermediates1
2-(N-Hydroxy Ethyl-N-Methyl Amino)-1-Phenyl Propane-1-One Hcl (Hmpp)902267-47-4Intermediates1
2-(Piperidin-4-Yl)-1H-Benzoimidazole38385-95-4Intermediates1
2-Amino-3-Hydroxy Pyridine16867-03-1Intermediates1
2-Amino-3-[1,2-Dihydro-2-Oxo-Quinoline-4-Yl] Propanoic Acid 2Hcl-2H2O5162-90-3Intermediates1
2-Amino-3-[1,2-Dihydro-2-Oxo-Quinoline-4-Yl]Propanoic Acid Dihcl Dihydrate132210-24-3Intermediates1
2-Amino-5-Methylthiophene-3-Carbonitrile138564-58-6Intermediates1
2-Aminopyrimidine109-12-6Intermediates1
2-Benzoyl-1H-Pyrrole7697-46-3Intermediates1
2-Bromopropene557-93-7Intermediates1
2-Chloro-5-Bromo Pyrimidine32779-36-5Intermediates1
2-Chloroethyl Ethyl Ether628-34-2Intermediates1
2-Chloropyrimidine1722-12-9Intermediates1
2-Ethoxyethyl-4-Methylbenzenesulfonate17178-11-9Intermediates1
2-Fluoro-5-[(Z)-(3-Oxo-1(3H)-Isobenzofuranylidene)Methyl]Benzonitrile1379825-89-4Intermediates1
2-Fluorobenzene Carbothioamide75907-82-3Intermediates1
2-Hydroxy-3-Nitrobenzoic Acid85-38-1Intermediates1
2-Methoxy-5-((R)-2-((R)-1-Phenyl Ethylamino)Propyl)Benzenesulfonamide116091-64-6Intermediates1
2-[1-(Ethylsulfonyl)-3-Azetidinylidene]Acetonitrile 1187595-85-2Intermediates1
2-[4-(4-Chlorobutanoyl)phenyl]-2-Methyl propionic acid methyl ester154477-54-0Intermediates1
2-[4-(Aminomethyl)Phenoxy]-N,N-Dimethylethanamine20059-73-8Intermediates1
2-[4-[1-(4,4-Dimethyl-5H-Oxazol-2-Yl)-1-Methyl-Ethyl]Phenyl] Ethyl-4-Methylbenzenesulfonate202189-76-2Intermediates1
2-[benzyl(methyl)amino]-1-(3-hydroxyphenyl)ethan-1-one hydrochloride71786-67-9Intermediates1
2-methyl-4-(2-methyl-benzoylamino)-benzoic acid317374-08-6Intermediates1
3 -Hydroxyacetophenone121-71-1Intermediates1
3,3-Tetramethyleneglutaricanhydride5662-95-3Intermediates1
3,3-Tetramethyleneglutarimide1075-89-4Intermediates1
3,4-(Methylenedioxyphenyl)Ethylamine (Hpa)1484-85-1Intermediates1
3,4-Di-Ethoxy Phenyl Acetic Acid38464-04-9Intermediates1
3,4-Di-Ethoxy Phenyl Ethyl Amine61381-04-2Intermediates1
3,4-Dimethoxy Phenyl Acetic Acid93-40-3Intermediates1
3,5-Dichlorobenzoyl Chloride2905-62-6Intermediates1
3,5-Difluorobenzyl Bromide141776-91-2Intermediates1
3,6-Pyridazinedione, 1,2-dihydro-4-(1-methylethyl)-920509-32-6Intermediates0
3-(Methylamino)-1-Phenylpropan-1-Ol42142-52-9Intermediates1
3-(Trifluoromethyl)-5,6,7,8-Tetrahydro- [1,2,4]Triazolo[4,3-A]Pyrazine Hydrochloride762240-92-6Intermediates1
3-Amino Pyrazole1820-80-0Intermediates1
3-Aminophthalic Acid5434-20-8Intermediates1
3-Aminopiperidine-2,6-Dione Hydrochloride24666-56-6Intermediates1
3-Bromo-4-Methylpyridine3430-22-6Intermediates1
3-Butyn-1-Ol927-74-2Intermediates1
3-Chloro-1-Phenylpropan-1-Ol18776-12-0Intermediates1
3-Chloro-1-Phenylpropan-1-One936-59-4Intermediates1
3-Chloro-1-Phenylpropan-1-One34841-35-5Intermediates0
3-Chloro-4-Nitrophenol491-11-2Intermediates1
3-Cyanobenzaldehyde24964-64-5Intermediates1
3-Ethyl-4-Methyl-2-Oxo-N-Phenethyl-2H-Pyrrole-1(5H)- Carboxamide247098-18-6Intermediates1
3-Ethyl-4-Methyl-3-Pyrroline-2-One [Empo]766-36-9Intermediates1
3-Fluoro-4-Nitrobenzoic Acid403-21-4Intermediates1
3-Isochromanone4385-35-7Intermediates1
3-Methoxy-4-Methylbenzonitrile3556-60-3Intermediates1
3-Methoxyphenylacetonitrile19924-43-7Intermediates1
3-Tert-Butyl-6-Ethylsulfanyl-1H-1,3,5-Triazine-2,4-Dione1360105-53-8Intermediates1
3-[(3-Bromo-4-Fluorophenyl)Methylene]-1(3H)-Isobenzofuranone63964-50-1Intermediates1
4'-Ethylpropiophenone27465-51-6Intermediates1
4-(1H-Pyrazol-4-Yl)-7-[[2-(Trimethylsilyl)Ethoxy]Methyl]-7H-Pyrrolo[2,3-D]Pyrimidine941685-27-4Intermediates1
4-(2-(3-Ethyl-4-Methyl-2-Oxo-2,5-Dihydro-1H-Pyrrole-1- Carboxamido)Ethyl)Benzene-1-Sulfonyl Chloride119043-16-2Intermediates1
4-(3-Chloro-4-Nitrophenoxy)-7-Methoxy-6-Quinolinecarboxamide2023825-93-4Intermediates1
4-(4-Fluorobenzoyl)Butyric Acid149437-76-3Intermediates1
4-(4-Phenylbutoxy)Benzoic Acid30131-16-9Intermediates1
4-(Ethylaminomethyl)Pyridine33403-97-3Intermediates1
4-Amino-2-Methyl-10H-Thieno [2, 3-B] [1, 5] Benzodiazepine Hydrochloride138564-60-0Intermediates1
4-Amino-3-Hydroxy Benzoic Acid2374-03-0Intermediates1
4-Amino-3-Methoxy Benzoic Acid2486-69-3Intermediates1
4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene461432-23-5Intermediates1
4-Bromo-2-Chloro Iodobenzene31928-47-9Intermediates1
4-Bromo-2-Chlorobenzonitrile154607-01-9Intermediates1
4-Bromo-2-Methoxyaniline59557-91-4Intermediates1
4-Bromomethyl-1,2-Dihydroquinoline-2-One4876-10-2Intermediates1
4-Chloro-2-Butanone6322-49-2Intermediates1
4-Chloro-7-Methoxy-6-Quinolinecarboxamide417721-36-9Intermediates1
4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine479633-63-1Intermediates1
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine3680-69-1Intermediates2
4-Chloropyridine Hcl7379-35-3Intermediates1
4-Fluorobenzoyl Chloride403-43-0Intermediates1
4-Guanidinobenzoic Acid Hydrochloride42823-46-1Intermediates1
4-Nitrophenylaceticacid104-03-0Intermediates1
4-Pentyn-1-Ol5390-04-5Intermediates1
4-Phenylbutan-1-Ol 3360-41-6Intermediates1
4-Toluenesulphonic Acid Propyl Ester599-91-7Intermediates1
4-[(3-Bromo-4-Fluorophenyl)Methyl]-1(2H)-Phthalazinone1062292-60-7Intermediates1
4-[(5-Bromo-2-Chlorophenyl)Methyl]Phenol864070-18-8Intermediates1
4-[[(4-Fluorophenyl)Imino]Methyl]-Phenol3382-63-6Intermediates1
5-(2-Aminopropyl)-2 Methoxybenzenesulfonamide112244-38-9Intermediates1
5-Aminoindazole19335-11-6Intermediates1
5-Benzoyl-2,3-Dihydro-1H-Pyrrolizine-1-Carboxylic Acid74103-06-3Intermediates1
5-Bromo-2-Chloro-4'-Ethoxydiphenylmethane461432-23-5Intermediates1
5-Bromo-2-Chlorobenzoic Acid21739-92-4Intermediates1
5-Bromo-2-Chlorophenyl)(4-Fluorophenyl)Methanone915095-85-1Intermediates1
5-Bromo-2-Iodobenzoic Acid21740-00-1Intermediates1
5-Bromo-2-Methyl Pyrimidine7752-78-5Intermediates1
5-Chloro-2-(Methylthio)Pyrimidine-4-Carboxylic Acid61727-33-1Intermediates1
5-Methyl-2-[(2-Nitrophenyl) Amino]Thiophene-3-Carbonitrile138564-59-7Intermediates1
5-Nitrosalicylic Acid96-97-9Intermediates1
5-[(3,4-Dihydro-4-Oxo-1-Phthalazinyl)Methyl]-2-Fluorobenzonitrile1021298-68-9Intermediates1
6-(4-amino-2,6-dichlorophenoxy)-4-isopropylpyridazin-3(2H)-one(WXG00197)920509-28-0Intermediates0
6-Cyano-2-Naphthol52927-22-7Intermediates1
7-Bromobenzo[d][1,3]dioxole-4-carbonitrile1898014-67-9Intermediates1
7-Chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one160129-45-3Intermediates1
7-Ethyltryptophol41340-36-7Intermediates1
9-[(R)-2-(Phosphonomethoxy)Propyl] Adenine Monohydrate [Pmpa]206184-49-8Intermediates1
Acetonitrile, 2-(3-Azetidinylidene)-, Hydrochloride (1:1)1314910-43-4Intermediates1
Cyclopropyl-1-Piperazinylmethanone As Hcl59878-57-8Intermediates1
DL-Lysine 50%70-54-2Intermediates0
Di-tert-butyl chloromethyl phosphate229625-50-7Intermediates1
Diethyl 2,2,14,14-tetramethyl-8-oxopentadecanedioate738606-43-4Intermediates1
Diethyl 2-(2-Cyanoethyl)Malonate17216-62-5Intermediates1
Diethyl Acetamidomalonate1068-90-2Intermediates1
Diethyl [(4-Chlorobenzoyl)Amino][(2-Oxo-1,2-Dihydro-4-Quinolinyl)Methyl] Malonate1028268-32-7Intermediates1
Dihydroxyacetone phosphate57-04-5Intermediates0
Dimethyl P-(1,3-Dihydro-3-Oxo-1-Isobenzofuranyl)Phosphonate61260-15-9Intermediates1
Ethyl (3 R,4R,5 S)-4-Acetamido-5- Azido - 3 - (I -Ethylpropoxy)- I-Cyclohexene- I -Carboxylate [N-1]204255-06-1Intermediates1
Ethyl 2-((2-Morpholin-4-Yl)Cyclopent-2-En-1-Ylidene)Acetate380350-42-5Intermediates1
Ethyl 2-Oxopiperidine-3-Carboxylate3731-16-6Intermediates1
Ethyl 7-chloro-2,2-dimethylheptanoate2570179-39-2Intermediates1
Ethyl Methoxycrylene14442-38-7Intermediates1
Ethyl-3-Amino-1H-Pyrazole-4-Carboxylate6994-25-8Intermediates1
Isopropyl-Β-(D)-Thiogalactopyranoside 367-93-1Intermediates1
L-proline benzyl ester hydrochloride16652-71-4Intermediates1
Methyl 2 Oxo-2,3 Dihydro-1H-Pyrrolo[2,3-B] Pyridine-6-Carboxylate1227268-70-3Intermediates1
Methyl 2-(4-(2-Chloroethyl) Phenyl) -2-Methylpropanoate1181267-33-3Intermediates1
Methyl 2-(4-(4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butanoyl)phenyl)-2-methylpropanoate154477-55-1Intermediates1
Methyl 2-Hydroxy-3-Nitrobenzoate22621-41-6Intermediates1
Methyl 3-Hydroxy-4-Methoxybenzoate6702-50-7Intermediates1
Methyl 5-Hydroxypentanoate14273-92-8Intermediates1
Methyl-2-(4-(2-Chloroethyl)Phenyl)2-Methylpropanoate1181267-33-3Intermediates1
Methyl-2-(4-Nitrophenyl)Acetate2945-08-6Intermediates1
Molnupiravir intermediatesIntermediates0
N-(1,3-Dioxo-1,3-Dihydroisobenzofuran-4- Yl)Acetamide6296-53-3Intermediates1
N-(2 -Cyanobiphenyl-4-ylmethyl)-L-valine Methyl Ester Hydrochloride482577-59-3Intermediates1
N-(4-Aminophenyl)-N-Methyl-2-(4-Methylpiperazin-1-Yl)Acetamide262368-30-9Intermediates1
N-Acetyl-glucosamine thiazoline179030-22-9Intermediates0
N-Benzyl Tertiary Butyl Amine3378-72-1Intermediates1
N-Cyanoacetyl Urethane6629-04-5Intermediates1
N-Methyl- Carboxy- 2-Chloro Acetamidrazone155742-64-6Intermediates1
N-Methyl-1-((1R,4R)-4-(methyl(7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamideNAIntermediates1
N-Propyl Chloride540-54-5Intermediates1
N-[2-[4-(Aminosulfonyl)Phenyl]Ethyl]-3-Ethyl-2,5-Dihydro-4- Methyl-2-Oxo-1H-Pyrrole-1-Carboxamide [Sulphonamide]119018-29-0Intermediates1
N-ethyl-5-fluoro-2-hydroxy-N-isopropyl benzamide1549490-65-4Intermediates1
N’-4-Acetyl Cytosine14631-20-0Intermediates1
Oxalate salt of Benzyl (2S,5R)-5-((Benzyloxy)amino)piperidine -2-carboxylate1171080-45-7Intermediates1
Oxogluric acid328-50-7Intermediates0
Phenyl Boronicacid98-80-6Intermediates1
Phenylephrine Base59-42-7Intermediates1
Pivalamide754-10-9Intermediates1
Pyruvaldehyde78-98-8Intermediates0
Rimtuzalcap2167246-24-2Intermediates0
S-(+)-4-Phenyl-2-Oxazolidinone (S-Poz)99395-88-7Intermediates1
Sabatolimab2252262-24-9Intermediates0
Sodium Triacetoxyborohydride (Stab)56553-60-7Intermediates1
Tert-Butyl 3-(Cyanomethylene)Azetidine-1-Carboxylate1153949-11-1Intermediates1
Tert-Butyl 3-Oxoazetidine-1-Carboxylate398489-26-4Intermediates1
Tert-Butyl 6-[(1E)-2-[4-(4-Fluorophenyl)-6-(1-Methylethyl)-2- [Methyl(Methylsulfonyl)Amino]-5-Pyrimidinyl]Ethenyl]-2,2- Dimethyl289042-12-2Intermediates1
Tert-Butyl Carbazate 870-46-2Intermediates1
Tetrabutylammonium [(2S,5R)-2-Carbamoyl- 7-oxo-1,6-diazabicyclo [3.2.1] octan-6-yl] Sulfate1192651-80-1Intermediates1
Tiemonium Methylsulphate6504-57-0Intermediates1
Tri N-Butyl Phosphine998-40-3Intermediates1
Tri(O-Tolyl)Phosphine6163-58-2 Intermediates1
Tri-N-Butyl Tinhydride688-73-3Intermediates1
Triethyl Methanetricarboxylate 6279-86-3Intermediates1
Triethyl [5-Benzoyl-1H-Pyrrol-2-Yl]Methanetricarboxylate136116-84-2Intermediates1
Trimethoxy Dobutamine Hydrochloride51062-14-7Intermediates1
Uridine diphosphate glucose133-89-1Intermediates0
Vanillic acid121-34-6Intermediates0
Veratric Acid93-07-2Intermediates1