Mucolytics
Mucolytics are a vital subcategory of pharmaceutical active pharmaceutical ingredients (APIs) widely used in the treatment of respiratory conditions. Mucolytics are specifically designed to alleviate respiratory distress by enhancing the clearance of mucus from the airways.
These APIs work by breaking down the chemical bonds within mucus, reducing its viscosity and promoting its removal from the respiratory tract. By thinning the mucus, mucolytics facilitate easier expectoration and help to relieve congestion and cough associated with respiratory conditions such as chronic bronchitis, asthma, and cystic fibrosis.
One of the commonly used mucolytics is N-acetylcysteine (NAC), which acts as a precursor for the synthesis of glutathione—a powerful antioxidant. Glutathione helps to protect the respiratory system from oxidative stress and inflammation, promoting healthy lung function. NAC's mucolytic properties make it an effective treatment for conditions characterized by excessive mucus production.
Mucolytics can be formulated in various dosage forms, including oral tablets, effervescent granules, and inhalation solutions. The choice of formulation depends on the target condition and the desired mode of administration.
Overall, mucolytics play a crucial role in the management of respiratory disorders by improving mucus clearance and reducing airway obstruction. These pharmaceutical APIs offer relief to patients suffering from respiratory conditions, promoting better breathing and overall quality of life.
| Name | CAS number |
|---|---|
| Acetylcysteine | 616-91-1 |
| Ambroxol | 18683-91-5 |
| Bromhexine | 3572-43-8 |
| Carbocisteine | 638-23-3 |
| Cysteine hydrochloride | |
| Erdosteine | 84611-23-4 |
| L-Cysteine | 52-90-4 |
| L-Cystine | 56-89-3 |
| N-Acetylcysteine | |
| S-Carboxymethylcysteine-L-Lysinate | 49673-81-6 |