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Nateglinide | compare suppliers & send inquiries for free

Here you will find a list of producers, manufacturers and traders of Nateglinide. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
Aurobindo

MOQ: 10 kg
Type: Producer
Origin: India
India
Ind-Swift Labs.


Type: Producer
Origin: India
India
Cadila Pharma


Type: Producer
Origin: India
India
Dr. Reddy's


Type: Producer
Origin: India
India
Teva


Type: Producer
Origin: Israel
Unichem Labs.


Type: Producer
Origin: India
India
Cipla


Type: Producer
Origin: India
USV


Type: Producer
Origin: India
India

Looking for Nateglinide 105816-04-4?

API | Excipient name:
Nateglinide 
Synonyms:
 
Cas Number:
105816-04-4 
DrugBank number:
DB00731 
Unique Ingredient Identifier:
41X3PWK4O2

About Nateglinide

So, what does it do? Nateglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the meglitinide class of short-acting insulin secretagogues, which act by binding to β cells of the pancreas to stimulate insulin release. Nateglinide is an amino acid derivative that induces an early insulin response to meals decreasing postprandial blood glucose levels. It should only be taken with meals and meal-time doses should be skipped with any skipped meal.

Approximately one month of therapy is required before a decrease in fasting blood glucose is seen. Meglitnides may have a neutral effect on weight or cause a slight increase in weight. The average weight gain caused by meglitinides appears to be lower than that caused by sulfonylureas and insulin and appears to occur only in those naïve to oral antidiabetic agents. Due to their mechanism of action, meglitinides may cause hypoglycemia although the risk is thought to be lower than that of sulfonylureas since their action is dependent on the presence of glucose. In addition to reducing postprandial and fasting blood glucose, meglitnides have been shown to decrease glycosylated hemoglobin (HbA1c) levels, which are reflective of the last 8-10 weeks of glucose control. Meglitinides appear to be more effective at lowering postprandial blood glucose than metformin, sulfonylureas and thiazolidinediones. Nateglinide is extensively metabolized in the liver and excreted in urine (83%) and feces (10%). The major metabolites possess less activity than the parent compound. One minor metabolite, the isoprene, has the same potency as its parent compound.

Ask the supplier for a certificate of analysis to find out more about the quality of Nateglinide.

Nateglinide manufacturers | traders | suppliers
We have 8 companies offering Nateglinide from 2 different countries.

Get in contact with the supplier of your choice:

  • Aurobindo from India
  • Ind-Swift Labs. from India
  • Cadila Pharma from India
  • Dr. Reddy's from India
  • Teva from Israel
  • Unichem Labs. from India
  • Cipla from India
  • USV from India

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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