Necitumumab API Manufacturers
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Looking for Necitumumab API 906805-06-9?
- Description:
- Here you will find a list of producers, manufacturers and traders of Necitumumab. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Necitumumab
- Synonyms:
- Cas Number:
- 906805-06-9
- DrugBank number:
- DB09559
- Unique Ingredient Identifier:
- 2BT4C47RUI
About Necitumumab
More information about this product: Necitumumab is an intravenously administered recombinant monoclonal IgG1 antibody used in the treatment of non-small cell lung cancer (NSCLC) as an EGFR antagonist. It functions by binding to epidermal growth factor receptor (EGFR) and prevents binding of its ligands, a process that is involved in cell proliferation, metastasis, angiogenesis, and malignant progression. Binding of necitumumab to EGFR induces receptor internalization and degradation, thereby preventing further activation of EGFR which is beneficial in NSCLC as many patients have increased protein expression of EGFR. Necitumumab is approved for use in combination with cisplatin and gemcitabine as a first-line treatment for metastatic squamous non-small cell lung cancer (NSCLC).
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