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Ciliary neurotrophic factor
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Looking for Ciliary neurotrophic factor API 133423-39-9?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Ciliary neurotrophic factor. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Ciliary neurotrophic factor
- Synonyms:
- allogenic retinal epithelial cells transfected with plasmid vector expressing ciliary neurotrophic growth factor , CILIARY NEUROTROPHIC FACTOR , Ciliary neurotrophic factor - Neurotech , CILIARY NEUROTROPHIC FACTOR (HUMAN) , Ciliary neurotrophic factor implant - Neurotech , HUMAN CILIARY NEUROTROPHIC FACTOR , HUMAN CNTF , NT 501 , NT-501 , NT501
- Cas Number:
- 133423-39-9
- DrugBank number:
- DB05344
- Unique Ingredient Identifier:
- CR102F038W
General Description:
Ciliary neurotrophic factor, identified by CAS number 133423-39-9, is a notable compound with significant therapeutic applications. Ciliary neurotrophic factor (NT-501) is Neurotech's lead product which is in two Phase II/III clinical trials for the treatment of visual loss associated with retinitis pigmentosa and a Phase II trial for the treatment of the dry form of age-related macular degeneration. Neurotech is also evaluating other factors that can be used with its proprietary delivery technology, Encapsulated Cell Technology (ECT), to treat additional retinal diseases.
Indications:
This drug is primarily indicated for: Investigated for use/treatment in eye disorders/infections, macular degeneration, and retinal disorders (unspecified). Its use in specific medical scenarios underscores its importance in the therapeutic landscape.
Mechanism of Action:
Ciliary neurotrophic factor functions by: NT-501 is an intraocular, cell containing polymer implant designed to provide the continuous, long-term release of the therapeutic protein, Ciliary Neurotrophic Factor (CNTF), directly into the back of the eye by means of the Company's proprietary Encapsulated Cell Technology (ECT). This mechanism highlights the drug's role in inhibiting or promoting specific biological pathways, contributing to its therapeutic effects.
Classification:
Ciliary neurotrophic factor belongs to the None, classified under the direct parent group Peptides. This compound is a part of the Organic Compounds, falling under the Organic Acids superclass, and categorized within the Carboxylic Acids and Derivatives class, specifically within the Amino Acids, Peptides, and Analogues subclass.
Categories:
Ciliary neurotrophic factor is categorized under the following therapeutic classes: Amino Acids, Peptides, and Proteins, Biological Factors, Intercellular Signaling Peptides and Proteins, Nerve Growth Factors, Nerve Tissue Proteins, Peptides, Proteins. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Ciliary neurotrophic factor is a type of Other substances
The pharmaceutical industry encompasses a diverse range of active pharmaceutical ingredients (APIs) that are used in the production of various medications. One category of APIs is known as other substances. This category includes substances that do not fall under the conventional classifications such as antibiotics, analgesics, or antihypertensives.
Other substances in pharmaceutical APIs consist of a broad array of chemical compounds with unique properties and applications. These substances play a crucial role in the formulation and development of specialized medications, catering to specific therapeutic needs. The category encompasses various substances like excipients, solvents, stabilizers, and pH adjusters.
Excipients are inert substances that aid in the manufacturing process and enhance the stability, bioavailability, and patient acceptability of pharmaceutical formulations. Solvents are used to dissolve other ingredients and facilitate their incorporation into the final product. Stabilizers ensure the integrity and shelf life of medications by preventing degradation or chemical changes. pH adjusters help maintain the desired pH level of a formulation, which can influence the drug's efficacy and stability.
Pharmaceutical manufacturers carefully select and incorporate specific other substances into their formulations, adhering to regulatory guidelines and quality standards. These substances undergo rigorous testing and evaluation to ensure their safety, efficacy, and compatibility with the desired pharmaceutical product. By employing other substances in API formulations, pharmaceutical companies can optimize drug delivery, improve patient compliance, and enhance therapeutic outcomes.
In summary, the other substances category of pharmaceutical APIs comprises a diverse range of chemicals, including excipients, solvents, stabilizers, and pH adjusters. These substances contribute to the formulation, stability, and performance of medications, enabling pharmaceutical manufacturers to develop specialized products that meet specific therapeutic requirements.
