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Dutogliptin
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Looking for Dutogliptin API 852329-66-9?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Dutogliptin. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Dutogliptin
- Synonyms:
- Cas Number:
- 852329-66-9
- DrugBank number:
- DB11723
- Unique Ingredient Identifier:
- 38EAO245ZX
General Description:
Dutogliptin, identified by CAS number 852329-66-9, is a notable compound with significant therapeutic applications. Dutogliptin has been investigated for the treatment of Diabetes Mellitus, Type II.
Half-life:
The half-life of Dutogliptin is an important consideration for its dosing schedule: 10-13 hours. This determines the duration of action and helps in formulating effective dosing regimens.
Mechanism of Action:
Dutogliptin functions by: Dutogliptin is a potent and selective inhibitor of DPP4, a serine protease that has emerged as an important target for the treatment of type 2 diabetes. Inhibiting DPP4 increases the physiological levels of regulatory peptides, such as GLP-1, an important modulator of insulin response and digestion. This mechanism highlights the drug's role in inhibiting or promoting specific biological pathways, contributing to its therapeutic effects.
Classification:
Dutogliptin belongs to the class of organic compounds known as alpha amino acid amides. These are amide derivatives of alpha amino acids, classified under the direct parent group Alpha amino acid amides. This compound is a part of the Organic compounds, falling under the Organic acids and derivatives superclass, and categorized within the Carboxylic acids and derivatives class, specifically within the Amino acids, peptides, and analogues subclass.
Categories:
Dutogliptin is categorized under the following therapeutic classes: Acids, Acids, Noncarboxylic, Agents causing angioedema, Blood Glucose Lowering Agents, Boron Compounds, DPP-IV Inhibitors. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Dutogliptin is a type of Other substances
The pharmaceutical industry encompasses a diverse range of active pharmaceutical ingredients (APIs) that are used in the production of various medications. One category of APIs is known as other substances. This category includes substances that do not fall under the conventional classifications such as antibiotics, analgesics, or antihypertensives.
Other substances in pharmaceutical APIs consist of a broad array of chemical compounds with unique properties and applications. These substances play a crucial role in the formulation and development of specialized medications, catering to specific therapeutic needs. The category encompasses various substances like excipients, solvents, stabilizers, and pH adjusters.
Excipients are inert substances that aid in the manufacturing process and enhance the stability, bioavailability, and patient acceptability of pharmaceutical formulations. Solvents are used to dissolve other ingredients and facilitate their incorporation into the final product. Stabilizers ensure the integrity and shelf life of medications by preventing degradation or chemical changes. pH adjusters help maintain the desired pH level of a formulation, which can influence the drug's efficacy and stability.
Pharmaceutical manufacturers carefully select and incorporate specific other substances into their formulations, adhering to regulatory guidelines and quality standards. These substances undergo rigorous testing and evaluation to ensure their safety, efficacy, and compatibility with the desired pharmaceutical product. By employing other substances in API formulations, pharmaceutical companies can optimize drug delivery, improve patient compliance, and enhance therapeutic outcomes.
In summary, the other substances category of pharmaceutical APIs comprises a diverse range of chemicals, including excipients, solvents, stabilizers, and pH adjusters. These substances contribute to the formulation, stability, and performance of medications, enabling pharmaceutical manufacturers to develop specialized products that meet specific therapeutic requirements.
