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Emricasan
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Looking for Emricasan API 254750-02-2?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Emricasan. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Emricasan
- Synonyms:
- Emricasán , Emricasanum
- Cas Number:
- 254750-02-2
- DrugBank number:
- DB05408
- Unique Ingredient Identifier:
- P0GMS9N47Q
General Description:
Emricasan, identified by CAS number 254750-02-2, is a notable compound with significant therapeutic applications. Emricasan is the first caspase inhibitor tested in human which has received orphan drug status by FDA. It is developed by Pfizer and made in such a way that it protects liver cells from excessive apoptosis.
Indications:
This drug is primarily indicated for: Investigated for use/treatment in hepatitis (viral, C), liver disease, and transplantation (organ or tissue). Its use in specific medical scenarios underscores its importance in the therapeutic landscape.
Mechanism of Action:
Emricasan functions by: IDN-6556 significantly improves markers of liver damage in patients infected with the Hepatitis C virus (HCV), an infection that affects up to 170m patients worldwide. IDN-6556 represents a new class of drugs that protect the liver from inflammation and cellular damage induced by viral infections and other causes. Various studies have also shown that it significantly lowers aminotransferase activity in HCV patients and appeared to be well tolerated. This mechanism highlights the drug's role in inhibiting or promoting specific biological pathways, contributing to its therapeutic effects.
Classification:
Emricasan belongs to the class of organic compounds known as hybrid peptides. These are compounds containing at least two different types of amino acids (alpha, beta, gamma, delta) linked to each other through a peptide bond, classified under the direct parent group Hybrid peptides. This compound is a part of the Organic compounds, falling under the Organic acids and derivatives superclass, and categorized within the Peptidomimetics class, specifically within the Hybrid peptides subclass.
Categories:
Emricasan is categorized under the following therapeutic classes: Acids, Acyclic, Fatty Acids, Fatty Acids, Volatile, Lipids, Valerates. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Emricasan is a type of Other substances
The pharmaceutical industry encompasses a diverse range of active pharmaceutical ingredients (APIs) that are used in the production of various medications. One category of APIs is known as other substances. This category includes substances that do not fall under the conventional classifications such as antibiotics, analgesics, or antihypertensives.
Other substances in pharmaceutical APIs consist of a broad array of chemical compounds with unique properties and applications. These substances play a crucial role in the formulation and development of specialized medications, catering to specific therapeutic needs. The category encompasses various substances like excipients, solvents, stabilizers, and pH adjusters.
Excipients are inert substances that aid in the manufacturing process and enhance the stability, bioavailability, and patient acceptability of pharmaceutical formulations. Solvents are used to dissolve other ingredients and facilitate their incorporation into the final product. Stabilizers ensure the integrity and shelf life of medications by preventing degradation or chemical changes. pH adjusters help maintain the desired pH level of a formulation, which can influence the drug's efficacy and stability.
Pharmaceutical manufacturers carefully select and incorporate specific other substances into their formulations, adhering to regulatory guidelines and quality standards. These substances undergo rigorous testing and evaluation to ensure their safety, efficacy, and compatibility with the desired pharmaceutical product. By employing other substances in API formulations, pharmaceutical companies can optimize drug delivery, improve patient compliance, and enhance therapeutic outcomes.
In summary, the other substances category of pharmaceutical APIs comprises a diverse range of chemicals, including excipients, solvents, stabilizers, and pH adjusters. These substances contribute to the formulation, stability, and performance of medications, enabling pharmaceutical manufacturers to develop specialized products that meet specific therapeutic requirements.
