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Pegloticase API Manufacturers
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Looking for Pegloticase API 885051-90-1?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Pegloticase. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Pegloticase
- Synonyms:
- Puricase
- Cas Number:
- 885051-90-1
- DrugBank number:
- DB09208
- Unique Ingredient Identifier:
- R581OT55EA
About Pegloticase
Here, you can find what Pegloticase is used for, in short. Pegloticase is a recombinant porcine-like uricase drug indicated for the treatment of severe, treatment-refractory, chronic gout. Similarly to rasburicase, pegloticase metabolises the conversion of uric acid to allantoin. This reduces the risk of precipitate formation and development of gout, since allantoin is five to ten times more soluble than uric acid.
Pegloticase is a pegylated form of uricase which offers an extended half-life of ten-12 days compared to rasburicase's 8 hours. It also offers reduced immunogenicity due to the bulky PEG group. The longer haf-life allows for less frequent dosing at once every 2-4 weeks making pegloticase more convenient for chronic use.
Check who is selling Pegloticase in the overview above.
