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Thyrotropin Alfa
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Looking for Thyrotropin Alfa API 194100-83-9?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Thyrotropin Alfa. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Thyrotropin Alfa
- Synonyms:
- rTSH , Thyroid stimulating hormone , Thyrotrophin-alfa , Thyrotrophin-alpha , Thyrotropin , Thyrotropin-a , Thyrotropin-alpha , Thytrophin , TSH
- Cas Number:
- 194100-83-9
- DrugBank number:
- DB00024
- Unique Ingredient Identifier:
- AVX3D5A4LM
About Thyrotropin Alfa
Some technical information about this product: Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests in patients who have or have had thyroid cancer. It is also used along with a radioactive agent to destroy remaining thyroid tissue in certain patients who have had their thyroid gland removed because of thyroid cancer. It is a heterodimeric glycoprotein comprised of two non-covalently linked subunits, an alpha subunit of 92 amino acid residues containing two N-linked glycosylation sites and a beta subunit of 112 residues containing one N-linked glycosylation site. The alpha subunit of thyrotropin alfa, which is the effector region responsible for the stimulation of adenylate cyclase, displays close structural similarity with the alpha subunit of human chorionic gonadotropin (hCG), luteinizing hormone (LH), and follicle-stimulating hormone (FSH).
The beta subunit (TSHB) bestows its receptor specificity due to the uniqueness to TSH. The amino acid sequence of thyrotropin alfa is identical to that of human pituitary thyroid stimulating hormone.
Check who is selling Thyrotropin alfa in the overview above.
