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Looking for Vortioxetine 508233-74-7?
Want to know what Vortioxetine is used for? Vortioxetine is an atypical antipsychotic and antidepressant indicated for the treatment of major depressive disorder (MDD). It is classified as a serotonin modulator and simulator (SMS) as it has a multimodal mechanism of action towards the serotonin neurotransmitter system whereby it simultaneously modulates one or more serotonin receptors and inhibits the reuptake of serotonin. More specifically, vortioxetine acts via the following biological mechanisms: as a serotonin reuptake inhibitor (SRI) through inhibition of the serotonin transporter, as a partial agonist of the 5-HT1B receptor, an agonist of 5-HT1A, and an antagonist of the 5-HT3, 5-HT1D, and 5-HT7 receptors. SMSs were developed because there are many different subtypes of serotonin receptors, however, not all of these receptors appear to be involved in the antidepressant effects of SRIs.
Some serotonin receptors seem to play a relatively neutral or insignificant role in the regulation of mood, but others, such as 5-HT1A autoreceptors and 5-HT7 receptors, appear to play an oppositional role in the efficacy of SRIs in treating depression.
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Vortioxetine manufacturers | traders | suppliers
We have 14 companies offering Vortioxetine from 3 different countries.
Get in contact with the supplier of your choice:
- Shandong Octagon Chemicals Limited from China
- Lupin from India
- Zhejiang Huahai Pharma from China
- Alembic Pharma from India
- Hetero Labs from India
- Dipharma Francis S.r.l. from Italy
- Macleods Pharma from India
- MSN Pharma from India
- Unichem Labs. from India
- Cadila Healthcare from India
- Apicore from United States
- Raks Pharma from India
- Cipla from India
- ALP PHARM from China
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