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Looking for Abatacept API 332348-12-6?
- Description:
- Here you will find a list of producers, manufacturers and traders of Abatacept. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Abatacept
- Synonyms:
- CTLA4-Ig , CTLA4-IgG4m , CTLA4Ig
- Cas Number:
- 332348-12-6
- DrugBank number:
- DB01281
- Unique Ingredient Identifier:
- 7D0YB67S97
About Abatacept
So, what does it do? Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1). Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 9200 Da and it is a homodimer of two homologous polypeptide chains of 357 amino acids each. It is produced through recombinant DNA technology in mammalian CHO cells. The drug has activity as a selective co-stimulation modulator with inhibitory activity on T lymphocytes.
Although approved for the treatment of rheumatoid arthritis, Repligen has entered a slightly different formulation of CTLA4-Ig into clinical trials (RG2077).
Ask the supplier for a certificate of analysis to find out more about the quality of Abatacept.
Abatacept manufacturers | traders | suppliers
We have 1 companies offering Abatacept produced in 1 different countries.
Get in contact with the supplier of your choice:
- LGM Pharma from United States, product country of origin World
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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