Temozolomide API Manufacturers

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TOP RANKING

Located in:

Iran

Producer

Produced in:

Iran

Established in: 1956

MOQ: 1 kg

Employees: 200+

Expertise in Low Volume, High Value (LVHV) APIs

Technical knowledge for high-tech API production

therapeutic production sites with GMP compliance

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

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TOP RANKING

Located in:

India

Produced in:

India

Established in: 1989

MOQ: -

Employees: 5000+

6 production facilities approved by USFDA, AGES-Austria, PMDA, WHO

R&D Centers with capabilities of ANDAs, DMFs and NDDS

462+ patents filed for drug substances and polymorphs

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  • DMF

  • + 0

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  • WC

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  • BSE/TSE

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HIGHLIGHTED

Located in:

India

Produced in:

India

Established in: 2012

MOQ: 1 kg

Employees: 50+

Diverse portfolio of APIs and Nutra products

Focus on Hormones Oncology and Peptides with the highest quality

Leading manufacturer of ALpha Lipoic Acid

  • CoA

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  • FDA

  • DMF

  • + 0

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HIGHLIGHTED

Located in:

Turkey

Producer

Produced in:

Turkey

Established in: 2022

MOQ: -

Employees: 100+

Operating on GMP guidelines with the most recent technologies and equipment

High-quality products at unrivaled prices

Specialize in Narcotic and Non-Narcotic APIs

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  • DMF

  • + 0

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Produced in:

Unknown

Established in: 1963

MOQ: -

Employees: 800+

World’s 1st exclusive API distributor

Portfolio of 600+ APIs

>250 clients in Europe

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Located in:

India
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Located in:

India

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Located in:

China
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Located in:

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Taiwan
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Located in:

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Looking for Temozolomide API 85622-93-1?

Description:
Here you will find a list of producers, manufacturers and traders of Temozolomide. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Temozolomide 
Synonyms:
CCRG 81045 , Methazolastone , Temodal , Temodar , Temozolodida , Temozolomid , Temozolomida , Temozolomidum , TMZ  
Cas Number:
85622-93-1 
DrugBank number:
DB00853 
Unique Ingredient Identifier:
YF1K15M17Y

About Temozolomide

Here you will find more information about Temozolomide. Temozolomide (Temodar and Temodal) is an oral alkylating agent used for the treatment of refractory anaplastic astrocytoma -- a type of cancerous brain tumor. Temozolomide is not active until it is converted at physiologic pH to the active form, 5-(3-methyltriazen-1-yl)imidazole-4-carboxamide (MTIC).

You can ask the supplier about all relevant certificates for the product such as CoA, Safety Data Sheet and DMF.

Temozolomide is a type of Alkylating agents


Alkylating agents are a vital subcategory of pharmaceutical active pharmaceutical ingredients (APIs) that play a significant role in cancer treatment. These compounds possess the ability to attach alkyl groups to the DNA molecule, effectively disrupting its structure and preventing cell replication. This mechanism of action makes alkylating agents potent chemotherapy drugs for various types of cancers.

Alkylating agents are often classified based on their chemical structure, which includes nitrogen mustards, ethylenimines, nitrosoureas, and alkyl sulfonates, among others. Each subclass exhibits unique chemical properties and therapeutic applications. For instance, nitrogen mustards like cyclophosphamide and mechlorethamine are used to treat lymphomas and leukemia, while nitrosoureas such as carmustine and lomustine are effective against brain tumors.

The alkylating agents' mode of action involves the transfer of alkyl groups to cellular components, primarily DNA. This leads to the formation of DNA adducts, cross-links, and DNA strand breaks, ultimately hindering DNA replication and causing cell death. The indiscriminate nature of alkylating agents can also affect healthy cells, leading to various side effects such as bone marrow suppression and gastrointestinal disturbances.

Despite their potential side effects, alkylating agents remain valuable tools in cancer therapy due to their broad spectrum of activity against different types of tumors. Ongoing research focuses on developing more selective and targeted alkylating agents to improve their therapeutic index and minimize adverse effects. The use of alkylating agents in combination with other chemotherapy drugs or radiation therapy is also being explored to enhance treatment outcomes and reduce drug resistance.

In conclusion, alkylating agents are an essential subclass of pharmaceutical APIs widely employed in cancer treatment. Their ability to disrupt DNA structure and impede cell replication makes them effective against various types of tumors, although careful management of side effects is necessary. Ongoing advancements and research continue to refine their therapeutic potential in the fight against cancer.


Temozolomide (Alkylating agents), classified under Anticancer drugs


Anticancer drugs belong to the pharmaceutical API (Active Pharmaceutical Ingredient) category designed specifically to combat cancer cells. These powerful medications play a crucial role in cancer treatment and are developed to target and destroy cancerous cells, preventing their growth and spread.

Anticancer drugs are classified based on their mode of action and can include various types such as chemotherapy drugs, targeted therapy drugs, immunotherapy drugs, and hormonal therapy drugs. Chemotherapy drugs work by interfering with the cell division process, thereby inhibiting the growth of cancer cells. Targeted therapy drugs, on the other hand, are designed to attack specific molecules or genes involved in cancer growth, minimizing damage to healthy cells. Immunotherapy drugs stimulate the body's immune system to recognize and destroy cancer cells. Hormonal therapy drugs are used in cancers that are hormone-dependent, such as breast or prostate cancer, to block the hormones that fuel cancer cell growth.

These APIs are typically synthesized through complex chemical processes in state-of-the-art manufacturing facilities. Stringent quality control measures ensure the purity, potency, and safety of these drugs. Anticancer APIs undergo rigorous testing and adhere to stringent regulatory guidelines before being approved for clinical use.

Due to their critical role in cancer treatment, anticancer drugs are in high demand worldwide. Researchers and pharmaceutical companies continually strive to develop new and more effective APIs in this category to enhance treatment outcomes and minimize side effects. The ongoing advancements in the field of anticancer drug development offer hope for improved cancer therapies and better patient outcomes.



Temozolomide manufacturers | traders | suppliers

We have 18 companies offering Temozolomide produced in 7 different countries.

Get in contact with the supplier of your choice:

  • Tofigh Daru from Iran, product country of origin Iran
  • Shilpa Medicare Ltd from India, product country of origin India
  • Avanscure Lifesciences Pvt Ltd from India, product country of origin India
  • PluviaEndo from Turkey, product country of origin Turkey
  • TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
  • Ind-Swift Labs. from India, product country of origin India
  • Laurus Labs from India, product country of origin India
  • Dalian Wista Pharma Co Ltd from China, product country of origin China
  • Fujian South Pharma from China, product country of origin China
  • Formosa Labs from Taiwan, product country of origin Taiwan
  • Hubei Haosun Pharma from China, product country of origin China
  • Reliance Life Sciences from India, product country of origin India
  • Beijing Lunarsun Pharma from China, product country of origin China
  • Ampac Fine Chemicals from United States, product country of origin United States
  • Sun Pharma from India, product country of origin India
  • Hetero Drugs from India, product country of origin India
  • Cipla from India, product country of origin India
  • Hetero Labs from India, product country of origin India

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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