Mesalazine API Manufacturers

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Produced in:

World

Established in: 2005

MOQ: -

Employees: 200+

Portfolio of over 2,000 APIs

Precise quality control

End-to-end global regulatory support

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Produced in:

Unknown

Established in: 1963

MOQ: -

Employees: 800+

World’s 1st exclusive API distributor

Portfolio of 600+ APIs

>250 clients in Europe

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Produced in:

Italy

Established in: 1968

MOQ: 5 kg

Employees: 50+

Warehouse stock of nearly all APIs

GMP, GDP and ISO certified

Customisable (small-sized) packages

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Located in:

Germany

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Produced in:

Unknown

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Produced in:

India

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Produced in:

India

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Looking for Mesalazine API 89-57-6?

Description:
Here you will find a list of producers, manufacturers and distributors of Mesalazine. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Mesalazine 
Synonyms:
Asacol , Asacolitin , Canasa , Claversal , Fisalamine , Iialda , Lixacol , m-Aminosalicylic acid , Mesalamine , Mesalazina , Mesalazine , Mesalazinum , Mesasal , P-Aminosalicylsaeure , Pentasa , Rowasa , Salofalk , Mesalazine High density  
Cas Number:
89-57-6 
DrugBank number:
DB00244 
Unique Ingredient Identifier:
4Q81I59GXC

About Mesalazine

You can find a short description about Mesalazine here. An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease It is considered to be the active moiety of sulphasalazine. Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical agent Throughout the late seventies and the eighties, important research initiatives developed stable mesalazine formulations like the eudragit-S coating of Asacol brand mesalazine and the Pentasa brand's encapsulation of mesalazine within microgranules In the present day, contemporary research regarding novel methods to stabilize mesalazine continues and interest in the agent's capacity to decrease inflammatory activity and subsequently potentially reduce the risk of colorectal cancer in conditions like ulcerative colitis is maintained 1.

You can ask the supplier for more technical information about the product.

Mesalazine is a type of Aminosalicylates


Aminosalicylates are a vital subcategory of pharmaceutical active pharmaceutical ingredients (APIs) widely used in the treatment of various inflammatory bowel diseases (IBDs), including ulcerative colitis and Crohn's disease. These compounds exhibit anti-inflammatory properties that target the gastrointestinal tract, helping to alleviate symptoms and manage these chronic conditions effectively.

Aminosalicylates function by inhibiting the production of inflammatory mediators, such as prostaglandins and leukotrienes, which play a significant role in triggering inflammation in the gut. By reducing the levels of these compounds, aminosalicylates aid in the suppression of inflammation, leading to symptom relief and promoting mucosal healing.

Commonly prescribed aminosalicylates include mesalazine (also known as mesalamine), olsalazine, and sulfasalazine. These medications are available in various formulations, including oral tablets, capsules, and rectal suppositories or enemas. The choice of formulation depends on the severity and location of the disease within the gastrointestinal tract.

The use of aminosalicylates has been shown to effectively induce and maintain remission in patients with IBDs. They are generally well-tolerated, with few reported side effects. However, as with any medication, individuals may experience mild adverse reactions, such as nausea, abdominal discomfort, or headaches.

In conclusion, aminosalicylates are a crucial class of pharmaceutical APIs utilized in the treatment of inflammatory bowel diseases. Their anti-inflammatory properties and targeted action on the gastrointestinal tract make them valuable therapeutic options for managing these chronic conditions. Proper usage of aminosalicylates, as directed by healthcare professionals, can significantly improve the quality of life for individuals living with IBDs.


Mesalazine (Aminosalicylates), classified under Anti-inflammatory Agents


Anti-inflammatory agents are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) used to treat various inflammatory conditions. These agents play a vital role in alleviating pain, reducing swelling, and controlling inflammation in the body. They are widely employed in the management of diverse medical conditions, including arthritis, autoimmune disorders, asthma, and skin conditions like dermatitis.

Anti-inflammatory APIs primarily function by inhibiting the production of specific enzymes called cyclooxygenases (COX) and lipoxygenases (LOX). These enzymes are responsible for the synthesis of pro-inflammatory molecules known as prostaglandins and leukotrienes, respectively. By suppressing the activity of COX and LOX, anti-inflammatory agents effectively curtail the production of these inflammatory mediators, thereby mitigating inflammation.

Common examples of anti-inflammatory APIs include non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, aspirin, and naproxen. These agents exhibit analgesic, antipyretic, and anti-inflammatory properties. Another group of anti-inflammatory APIs includes corticosteroids, such as prednisone and dexamethasone, which are synthetic hormones that modulate the body's immune response to control inflammation.

In conclusion, anti-inflammatory agents are a vital category of pharmaceutical APIs widely used to manage inflammation-related disorders. They target enzymes involved in the synthesis of pro-inflammatory molecules, effectively reducing pain and swelling. NSAIDs and corticosteroids are commonly prescribed anti-inflammatory APIs due to their efficacy in controlling inflammation.



Mesalazine manufacturers | traders | suppliers

We have 24 companies offering Mesalazine produced in 10 different countries.

Get in contact with the supplier of your choice:

  • LGM Pharma from United States, product country of origin World
  • TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
  • Duchefa Farma B.V. from Netherlands, product country of origin Italy
  • Wanbury from India, product country of origin India
  • Ferring Therapeutics from India, product country of origin India
  • PLIVA from Czech Republic, product country of origin Czech Republic
  • ALP PHARM from China, product country of origin China
  • Lupin from India, product country of origin India
  • Maithri Drugs from India, product country of origin India
  • Zhejiang Sanmen Hengkang from China, product country of origin China
  • BEC Chemicals from India, product country of origin India
  • Corden Pharma from Germany, product country of origin Italy
  • Chemi S.p.A. from Italy, product country of origin Italy
  • Syntese from Denmark, product country of origin Denmark
  • Infar, S.A. from Spain, product country of origin Spain
  • Signa from Mexico, product country of origin Mexico
  • Zhejiang Chengyi from China, product country of origin China
  • Pharmazell from Germany, product country of origin India
  • Erregierre from Italy, product country of origin Italy
  • Cambrex, Karlskoga from Sweden, product country of origin Sweden
  • Ipca Labs. from India, product country of origin Unknown
  • Bayer from Germany, product country of origin Unknown
  • Sun Pharma from India, product country of origin India
  • Divis Labs. from India, product country of origin India

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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