Mesalazine

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Description:

Here you will find a list of producers, manufacturers and traders of Mesalazine. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.

API | Excipient name:

Mesalazine 

Synonyms:

Asacol , Asacolitin , Canasa , Claversal , Fisalamine , Iialda , Lixacol , m-Aminosalicylic acid , Mesalamine , Mesalazina , Mesalazine , Mesalazinum , Mesasal , P-Aminosalicylsaeure , Pentasa , Rowasa , Salofalk , Mesalazine High density  

Cas Number:

89-57-6 

DrugBank number:

DB00244 

Unique Ingredient Identifier:

4Q81I59GXC

Mesalazine is a type of Aminosalicylates

Aminosalicylates are a vital subcategory of pharmaceutical active pharmaceutical ingredients (APIs) widely used in the treatment of various inflammatory bowel diseases (IBDs), including ulcerative colitis and Crohn's disease. These compounds exhibit anti-inflammatory properties that target the gastrointestinal tract, helping to alleviate symptoms and manage these chronic conditions effectively.

Aminosalicylates function by inhibiting the production of inflammatory mediators, such as prostaglandins and leukotrienes, which play a significant role in triggering inflammation in the gut. By reducing the levels of these compounds, aminosalicylates aid in the suppression of inflammation, leading to symptom relief and promoting mucosal healing.

Commonly prescribed aminosalicylates include mesalazine (also known as mesalamine), olsalazine, and sulfasalazine. These medications are available in various formulations, including oral tablets, capsules, and rectal suppositories or enemas. The choice of formulation depends on the severity and location of the disease within the gastrointestinal tract.

The use of aminosalicylates has been shown to effectively induce and maintain remission in patients with IBDs. They are generally well-tolerated, with few reported side effects. However, as with any medication, individuals may experience mild adverse reactions, such as nausea, abdominal discomfort, or headaches.

In conclusion, aminosalicylates are a crucial class of pharmaceutical APIs utilized in the treatment of inflammatory bowel diseases. Their anti-inflammatory properties and targeted action on the gastrointestinal tract make them valuable therapeutic options for managing these chronic conditions. Proper usage of aminosalicylates, as directed by healthcare professionals, can significantly improve the quality of life for individuals living with IBDs.

Mesalazine (Aminosalicylates), classified under Anti-inflammatory Agents

Anti-inflammatory agents are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) used to treat various inflammatory conditions. These agents play a vital role in alleviating pain, reducing swelling, and controlling inflammation in the body. They are widely employed in the management of diverse medical conditions, including arthritis, autoimmune disorders, asthma, and skin conditions like dermatitis.

Anti-inflammatory APIs primarily function by inhibiting the production of specific enzymes called cyclooxygenases (COX) and lipoxygenases (LOX). These enzymes are responsible for the synthesis of pro-inflammatory molecules known as prostaglandins and leukotrienes, respectively. By suppressing the activity of COX and LOX, anti-inflammatory agents effectively curtail the production of these inflammatory mediators, thereby mitigating inflammation.

Common examples of anti-inflammatory APIs include non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, aspirin, and naproxen. These agents exhibit analgesic, antipyretic, and anti-inflammatory properties. Another group of anti-inflammatory APIs includes corticosteroids, such as prednisone and dexamethasone, which are synthetic hormones that modulate the body's immune response to control inflammation.

In conclusion, anti-inflammatory agents are a vital category of pharmaceutical APIs widely used to manage inflammation-related disorders. They target enzymes involved in the synthesis of pro-inflammatory molecules, effectively reducing pain and swelling. NSAIDs and corticosteroids are commonly prescribed anti-inflammatory APIs due to their efficacy in controlling inflammation.

• LGM Pharma from United States
• DKSH from Switzerland
• Duchefa Farma B.V. from Netherlands
• TIEFENBACHER API + Ingredients from Germany
• ALP PHARM from China
• Jiangsu Jubang from China
• Syntese from Denmark
• Chemi S.p.A. from Italy
• Corden Pharma from Germany
• Cadila Healthcare from India
• Zhejiang Sanmen Hengkang from China
• BEC Chemicals from India
• A.H.A. International from China
• Signa from Mexico
• Infar, S.A. from Spain
• Ferring Therapeutics from India
• Lupin from India
• Maithri Drugs from India
• PLIVA from Czech Republic
• Wanbury from India
• Zhejiang Chengyi from China
• Sun Pharma from India
• Bayer from Germany
• Cambrex, Karlskoga from Sweden
• Divis Labs. from India
• Erregierre from Italy
• Pharmazell from Germany
• Ipca Labs. from India

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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