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Looking for Cobicistat API 1004316-88-4?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Cobicistat. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Cobicistat
- Cas Number:
- 1004316-88-4
- DrugBank number:
- DB09065
- Unique Ingredient Identifier:
- LW2E03M5PG
About Cobicistat
It's time for some technical information for the ones who understand chemistry: Cobicistat, marketed under the name Tybost (formerly GS-9350), indicated for treating infection with human immunodeficiency virus (HIV). Although it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered agents that are metabolized by CYP3A enzymes. More specifically, cobicistat is indicated to increase systemic exposure of atazanavir or darunavir (once daily dosing regimen) in combination with other antiretroviral agents in the treatment of HIV-1 infection. Increasing systemic exposure of anti-retrovirals (ARVs) without increasing dosage allows for better treatment outcomes and a decreased side effect profile.
Not sure if this is the exact product you're looking for? Contact the supplier by using the send inquiry button.
Cobicistat is a type of Anti HIV
The Anti-HIV pharmaceutical API subcategory encompasses a range of active pharmaceutical ingredients (APIs) specifically designed to combat the human immunodeficiency virus (HIV), which causes acquired immunodeficiency syndrome (AIDS). These APIs play a vital role in the development of effective antiretroviral therapy (ART) regimens used to manage and treat HIV infections.
The primary objective of Anti-HIV APIs is to target the various stages of the HIV life cycle, inhibiting viral replication and reducing the viral load in the patient's body. These APIs typically act through mechanisms such as reverse transcriptase inhibition, protease inhibition, integrase inhibition, and fusion inhibition.
Common Anti-HIV APIs include nucleoside reverse transcriptase inhibitors (NRTIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs), protease inhibitors (PIs), integrase inhibitors (INIs), and fusion inhibitors. Each class of API targets different stages of the virus's replication cycle, thereby preventing its spread and reducing the viral load.
These APIs undergo rigorous testing and are subject to strict regulatory guidelines to ensure their safety and efficacy. Pharmaceutical companies and research institutions employ advanced techniques like high-performance liquid chromatography (HPLC), mass spectrometry, and nuclear magnetic resonance (NMR) to analyze the purity, potency, and quality of Anti-HIV APIs.
The development and production of Anti-HIV APIs require expertise in synthetic organic chemistry, process optimization, and quality control. Pharmaceutical manufacturers must adhere to stringent quality standards, good manufacturing practices (GMP), and follow international guidelines to ensure the consistent production of high-quality Anti-HIV APIs.
Overall, Anti-HIV APIs are crucial components in the development of effective antiretroviral medications, playing a vital role in managing HIV infections and improving the quality of life for millions of people living with HIV/AIDS.
Cobicistat (Anti HIV), classified under Anti-infective Agents
Anti-infective agents are a vital category of pharmaceutical active pharmaceutical ingredients (APIs) used in the treatment of various infectious diseases. These agents play a crucial role in combating bacterial, viral, fungal, and parasitic infections. The demand for effective anti-infective APIs has grown significantly due to the increasing prevalence of drug-resistant microorganisms.
Anti-infective APIs encompass a wide range of substances, including antibiotics, antivirals, antifungals, and antiparasitics. Antibiotics are particularly important in fighting bacterial infections and are further categorized into different classes based on their mode of action and target bacteria. Antivirals are designed to inhibit viral replication and are essential in the treatment of viral infections such as influenza and HIV. Antifungals combat fungal infections, while antiparasitics are used to eliminate parasites that cause diseases like malaria and helminthiasis.
The development and production of high-quality anti-infective APIs require stringent manufacturing processes and adherence to regulatory standards. Pharmaceutical companies invest heavily in research and development to discover new and more effective anti-infective agents. Additionally, ensuring the safety, efficacy, and stability of these APIs is of utmost importance.
The global market for anti-infective APIs is driven by factors such as the rising incidence of infectious diseases, the emergence of new and drug-resistant pathogens, and the growing demand for improved healthcare infrastructure. Continuous advancements in pharmaceutical technology and the development of innovative drug delivery systems further contribute to the expansion of this market.
In conclusion, anti-infective agents are a critical category of pharmaceutical APIs that play a pivotal role in treating infectious diseases. Their effectiveness in combating various types of infections makes them essential components in the arsenal of modern medicine.
Cobicistat manufacturers | traders | suppliers
We have 5 companies offering Cobicistat produced in 3 different countries.
Get in contact with the supplier of your choice:
- Shanghai Acebright from China, product country of origin China
- Flamma from Italy, product country of origin Italy
- Honour Lab from India, product country of origin India
- MSN Life Sciences from India, product country of origin India
- Mylan from India, product country of origin India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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