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Rilpivirine
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Producer
Produced in:
Established in: 1952
MOQ: 25 kg
Employees: 550+
API manufacturing (Innovators, Generics and Highly Potent)
A tailor-made and flexible service approach
State-of-the-art analytical services including solid form and QbD laboratories
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Distributor
Produced in:
Established in: 2011
MOQ: 5 g
Employees: 10+
Fast Response and Good Communication
Willingness To Start From Small
Flexible Payment Terms
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Producer
Produced in:
Established in: 2021
MOQ: -
Employees: 19
API, Intermediates, Building Blocks, Impurities, Amino acids and Peptides
Small quantity APIs to commercial scale
GMP and USFDA certification based on quantity, order, assignment.
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Producer
Produced in:
Established in: 2006
MOQ: 1 kg
Employees: 50+
Backward integration with key APIs
Current Good Manufacturing Practices (cGMP)
Unique reaction capabilities
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Producer
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Looking for Rilpivirine API 500287-72-9?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Rilpivirine. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Rilpivirine
- Cas Number:
- 500287-72-9
- DrugBank number:
- DB08864
About Rilpivirine
Here, you can find what Rilpivirine is used for, in short. Rilpivirine is non-nucleoside reverse transcriptase inhibitor (NNRTI) which is used for the treatment of HIV-1 infections in treatment-naive patients. It is a diarylpyrimidine derivative, a class of molecules that resemble pyrimidine nucleotides found in DNA. The internal conformational flexibility of rilpivirine and the plasticity of it interacting binding site gives it a very high potency and an unlikely generation of resistance compared to other NNRTI's.
Rilpivirine was developed by Tilbotec, Inc. and FDA approved on May 20, 2011. On November 21, 2017, Rilpivirine, in combination with dolutegravir, was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named Juluca.
Do you want to buy this product? Send an inquiry to the listed suppliers that meets your quality requirements.
Rilpivirine is a type of Anti-HIV
The Anti-HIV category of pharmaceutical APIs comprises a range of active pharmaceutical ingredients (APIs) specifically designed to combat the human immunodeficiency virus (HIV). These APIs play a critical role in the development and production of antiretroviral drugs, which are used to treat HIV infections and prevent the progression to acquired immunodeficiency syndrome (AIDS).
Anti-HIV APIs work by targeting various stages of the HIV life cycle, inhibiting viral replication and reducing the viral load in the body. Some commonly used APIs in this category include nucleoside reverse transcriptase inhibitors (NRTIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs), protease inhibitors (PIs), and integrase inhibitors (INIs).
NRTIs, such as tenofovir and emtricitabine, act by blocking the reverse transcriptase enzyme, an essential component in the replication of the virus. NNRTIs, such as efavirenz and nevirapine, bind to the reverse transcriptase enzyme, preventing its proper functioning. PIs, like ritonavir and atazanavir, inhibit the protease enzyme, crucial for viral maturation and assembly. INIs, such as raltegravir and dolutegravir, target the integrase enzyme, impeding viral integration into the host's DNA.
These APIs are carefully synthesized and undergo rigorous quality testing to ensure their safety, efficacy, and compliance with regulatory standards. Pharmaceutical companies utilize these APIs as key building blocks to formulate antiretroviral medications, which are then prescribed to individuals living with HIV/AIDS worldwide.
Overall, the Anti-HIV API category plays a vital role in the ongoing battle against HIV/AIDS, offering effective treatment options and improved quality of life for patients affected by this challenging condition.
Rilpivirine manufacturers | traders | suppliers
We have 12 companies offering Rilpivirine produced in 4 different countries.
Get in contact with the supplier of your choice:
- Minakem from France, product country of origin France
- Shandong Octagon Chemicals Limited from China, product country of origin China
- SETV Global from India, product country of origin India
- Acura Labs from India, product country of origin India
- Shanghai Acebright from China, product country of origin China
- Laurus Labs from India, product country of origin India
- Shanghai Desano Chem. from China, product country of origin China
- MSN Pharma from India, product country of origin India
- Mylan from India, product country of origin India
- Hetero Drugs from India, product country of origin India
- Janssen Pharma from Belgium, product country of origin Unknown
- Cipla from India, product country of origin India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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