Zidovudine API Manufacturers & Suppliers
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Established in: 1987
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Looking for Zidovudine API 30516-87-1?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Zidovudine. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Zidovudine
- Synonyms:
- Azidothymidine , AZT , ZDV , Zidovudin , Zidovudinum
- Cas Number:
- 30516-87-1
- DrugBank number:
- DB00495
- Unique Ingredient Identifier:
- 4B9XT59T7S
About Zidovudine
More information about this product: A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription. It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS.
Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia.
Ask the supplier for a certificate of analysis to find out more about the quality of Zidovudine.
Zidovudine is a type of Anti-HIV
The Anti-HIV category of pharmaceutical APIs comprises a range of active pharmaceutical ingredients (APIs) specifically designed to combat the human immunodeficiency virus (HIV). These APIs play a critical role in the development and production of antiretroviral drugs, which are used to treat HIV infections and prevent the progression to acquired immunodeficiency syndrome (AIDS).
Anti-HIV APIs work by targeting various stages of the HIV life cycle, inhibiting viral replication and reducing the viral load in the body. Some commonly used APIs in this category include nucleoside reverse transcriptase inhibitors (NRTIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs), protease inhibitors (PIs), and integrase inhibitors (INIs).
NRTIs, such as tenofovir and emtricitabine, act by blocking the reverse transcriptase enzyme, an essential component in the replication of the virus. NNRTIs, such as efavirenz and nevirapine, bind to the reverse transcriptase enzyme, preventing its proper functioning. PIs, like ritonavir and atazanavir, inhibit the protease enzyme, crucial for viral maturation and assembly. INIs, such as raltegravir and dolutegravir, target the integrase enzyme, impeding viral integration into the host's DNA.
These APIs are carefully synthesized and undergo rigorous quality testing to ensure their safety, efficacy, and compliance with regulatory standards. Pharmaceutical companies utilize these APIs as key building blocks to formulate antiretroviral medications, which are then prescribed to individuals living with HIV/AIDS worldwide.
Overall, the Anti-HIV API category plays a vital role in the ongoing battle against HIV/AIDS, offering effective treatment options and improved quality of life for patients affected by this challenging condition.
Zidovudine manufacturers | traders | suppliers
We have 9 companies offering Zidovudine produced in 1 different countries.
Get in contact with the supplier of your choice:
- Sinoway industrial Co.,Ltd from China, product country of origin China
- Shanghai Desano Chem. from China, product country of origin China
- Shanghai Acebright from China, product country of origin China
- HEC Pharm from Germany, product country of origin Unknown
- Anhui Biochem United Pharma from China, product country of origin China
- Hetero Labs from India, product country of origin India
- Shaoxing Hantai Pharma from China, product country of origin China
- Cipla from India, product country of origin India
- Mylan from India, product country of origin India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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