Methylprednisolone hemisuccinate API Manufacturers

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Looking for Methylprednisolone hemisuccinate API 2921-57-5?

Description:
Here you will find a list of producers, manufacturers and distributors of Methylprednisolone hemisuccinate. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Methylprednisolone hemisuccinate 
Synonyms:
Methylprednisolone hydrogen succinate , Methylprednisolone succinate  
Cas Number:
2921-57-5 
DrugBank number:
DB14644 
Unique Ingredient Identifier:
5GMR90S4KN

General Description:

Methylprednisolone hemisuccinate, identified by CAS number 2921-57-5, is a notable compound with significant therapeutic applications. A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.

Pharmacodynamics:

Methylprednisolone hemisuccinate exerts its therapeutic effects through: Methylprednisolone sodium succinate (the sodium salt of methylprednisolone hemisuccinate) has the same metabolic and anti-inflammatory actions as methylprednisolone. When given parenterally and in equimolar quantities, the two compounds are equivalent in biologic activity. The drug's ability to modulate various physiological processes underscores its efficacy in treating specific conditions.

Categories:

Methylprednisolone hemisuccinate is categorized under the following therapeutic classes: Adrenal Cortex Hormones, Adrenals, Anti-Inflammatory Agents, Antineoplastic Agents, Antineoplastic Agents, Hormonal, Central Nervous System Agents, Compounds used in a research, industrial, or household setting, Corticosteroids, Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 Inducers, Cytochrome P-450 CYP3A4 Inducers (strength unknown), Cytochrome P-450 CYP3A5 Inducers, Cytochrome P-450 CYP3A5 Inducers (strength unknown), Cytochrome P-450 Enzyme Inducers, Fused-Ring Compounds, Glucocorticoids, Hormones, Hormones, Hormone Substitutes, and Hormone Antagonists, Neuroprotective Agents, Pregnadienes, Pregnadienetriols, Pregnanes, Protective Agents, Steroids. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.

Methylprednisolone hemisuccinate is a type of Anti-inflammatory Agents


Anti-inflammatory agents are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) used to treat various inflammatory conditions. These agents play a vital role in alleviating pain, reducing swelling, and controlling inflammation in the body. They are widely employed in the management of diverse medical conditions, including arthritis, autoimmune disorders, asthma, and skin conditions like dermatitis.

Anti-inflammatory APIs primarily function by inhibiting the production of specific enzymes called cyclooxygenases (COX) and lipoxygenases (LOX). These enzymes are responsible for the synthesis of pro-inflammatory molecules known as prostaglandins and leukotrienes, respectively. By suppressing the activity of COX and LOX, anti-inflammatory agents effectively curtail the production of these inflammatory mediators, thereby mitigating inflammation.

Common examples of anti-inflammatory APIs include non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, aspirin, and naproxen. These agents exhibit analgesic, antipyretic, and anti-inflammatory properties. Another group of anti-inflammatory APIs includes corticosteroids, such as prednisone and dexamethasone, which are synthetic hormones that modulate the body's immune response to control inflammation.

In conclusion, anti-inflammatory agents are a vital category of pharmaceutical APIs widely used to manage inflammation-related disorders. They target enzymes involved in the synthesis of pro-inflammatory molecules, effectively reducing pain and swelling. NSAIDs and corticosteroids are commonly prescribed anti-inflammatory APIs due to their efficacy in controlling inflammation.