Anticholinergics/Parasympathemimetics


Anticholinergics/Parasympathomimetics are a subcategory of pharmaceutical active pharmaceutical ingredients (APIs) widely used in the medical field. These compounds exhibit specific pharmacological actions by targeting the cholinergic system in the body.

Anticholinergics are drugs that block the action of acetylcholine, a neurotransmitter that regulates various bodily functions. By inhibiting the activity of acetylcholine, anticholinergics can have diverse therapeutic effects, including reducing muscle spasms, decreasing gastrointestinal motility, and alleviating symptoms associated with certain respiratory conditions.

On the other hand, parasympathomimetics, also known as cholinomimetics, mimic the action of acetylcholine by stimulating cholinergic receptors. These compounds enhance the parasympathetic nervous system, which is responsible for the "rest and digest" functions of the body. Parasympathomimetics are commonly used to treat conditions such as glaucoma, urinary retention, and Alzheimer's disease.

The use of anticholinergics/parasympathomimetics requires careful consideration and medical supervision due to their potential side effects, which can include dry mouth, blurred vision, urinary retention, constipation, and cognitive impairment. These medications are available in various forms, including tablets, capsules, patches, and inhalers, and their dosage is determined by the specific medical condition being treated.

Overall, anticholinergics/parasympathomimetics play a vital role in modern medicine, providing targeted therapeutic effects by modulating the cholinergic system. Their usage has significantly improved patient outcomes in various medical conditions and continues to be an important category of pharmaceutical APIs.

NameCAS numberCategoryAmount of suppliers
Aclidinium727649-81-2Anticholinergics/Parasympathemimetics1
Atropine51-55-8Anticholinergics/Parasympathemimetics26
Benzatropine86-13-5Anticholinergics/Parasympathemimetics7
Biperiden514-65-8Anticholinergics/Parasympathemimetics7
Cimetropium Bromide51598-60-8Anticholinergics/Parasympathemimetics3
Clidinium7020-55-5Anticholinergics/Parasympathemimetics4
Cyclopentolate512-15-2Anticholinergics/Parasympathemimetics9
Darifenacin133099-04-4Anticholinergics/Parasympathemimetics18
Dicyclomine77-19-0Anticholinergics/Parasympathemimetics8
Fesoterodine286930-02-7Anticholinergics/Parasympathemimetics15
Flavoxate15301-69-6Anticholinergics/Parasympathemimetics12
Glycopyrronium Bromide740028-90-4Anticholinergics/Parasympathemimetics16
Homatropine HydrobromideAnticholinergics/Parasympathemimetics2
Homatropine Methylbromide80-49-9Anticholinergics/Parasympathemimetics10
Hyoscyamine101-31-5Anticholinergics/Parasympathemimetics6
Imidafenacin170105-16-5Anticholinergics/Parasympathemimetics3
Ipratropium Bromide22254-24-6Anticholinergics/Parasympathemimetics20
Ipratropium Impurity E22235-74-1Anticholinergics/Parasympathemimetics1
Isopropamide7492-32-2Anticholinergics/Parasympathemimetics4
Mepenzolate25990-43-6Anticholinergics/Parasympathemimetics1
Methylscopolamine bromide155-41-9Anticholinergics/Parasympathemimetics6
Oxybutynin5633-20-5Anticholinergics/Parasympathemimetics14
Pirenzepine28797-61-7Anticholinergics/Parasympathemimetics4
PridinolAnticholinergics/Parasympathemimetics1
Propantheline298-50-0Anticholinergics/Parasympathemimetics1
Pyridostigmine155-97-5Anticholinergics/Parasympathemimetics9
Scopolamine51-34-3Anticholinergics/Parasympathemimetics13
Scopolamine butylbromide149-64-4Anticholinergics/Parasympathemimetics11
Tiotropium186691-13-4Anticholinergics/Parasympathemimetics16
Tropicamide1508-75-4Anticholinergics/Parasympathemimetics10
Umeclidinium869185-19-3Anticholinergics/Parasympathemimetics2