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Coumarin
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Looking for Coumarin API 91-64-5?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Coumarin. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Coumarin
- Synonyms:
- 1,2-benzopyrone , 2H-1-benzopyran-2-one , 2H-benzo(b)pyran-2-one , Coumarinic lactone , Cumarin
- Cas Number:
- 91-64-5
- DrugBank number:
- DB04665
- Unique Ingredient Identifier:
- A4VZ22K1WT
General Description:
Coumarin is a chemical compound identified by the CAS number 91-64-5. It is known for its distinct pharmacological properties and applications.
Classification:
Coumarin belongs to the class of organic compounds known as coumarins and derivatives. These are polycyclic aromatic compounds containing a 1-benzopyran moiety with a ketone group at the C2 carbon atom (1-benzopyran-2-one), classified under the direct parent group Coumarins and derivatives. This compound is a part of the Organic compounds, falling under the Phenylpropanoids and polyketides superclass, and categorized within the Coumarins and derivatives class, specifically within the None subclass.
Categories:
Coumarin is categorized under the following therapeutic classes: Anticoagulants, Benzopyrans, Cytochrome P-450 CYP2C9 Substrates, Cytochrome P-450 Substrates, Edema, drug therapy, Heterocyclic Compounds, Fused-Ring, Pyrans, Vitamin K Antagonists. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Coumarin is a type of Anticoagulants
Anticoagulants are a vital category of pharmaceutical active pharmaceutical ingredients (APIs) used to prevent and treat blood clotting disorders. These medications play a crucial role in various medical conditions, including deep vein thrombosis (DVT), pulmonary embolism (PE), and atrial fibrillation (AF). Anticoagulants work by inhibiting the formation of blood clots or by preventing existing clots from getting larger.
There are different types of anticoagulants available, including direct thrombin inhibitors, vitamin K antagonists, and factor Xa inhibitors. Direct thrombin inhibitors, such as dabigatran, directly target the enzyme thrombin to hinder clot formation. Vitamin K antagonists, like warfarin, interfere with the production of clotting factors that rely on vitamin K. Factor Xa inhibitors, such as rivaroxaban and apixaban, inhibit the activity of factor Xa, a crucial component in the clotting cascade.
Anticoagulants are commonly prescribed to patients at risk of developing blood clots or those with existing clotting disorders. They are often used during surgeries, such as hip or knee replacements, to minimize the risk of post-operative clot formation. Patients with AF, a condition characterized by irregular heart rhythm, may also be prescribed anticoagulants to prevent stroke caused by blood clots.
While anticoagulants offer significant benefits in preventing and treating clot-related conditions, they also carry potential risks, including bleeding complications. Patients taking anticoagulants require careful monitoring to ensure the right dosage is administered, as excessive anticoagulation can lead to hemorrhage. Regular blood tests and close medical supervision are essential to manage the delicate balance between preventing clots and avoiding excessive bleeding.
In conclusion, anticoagulants are a crucial category of pharmaceutical APIs used to prevent and treat blood clotting disorders. They function by inhibiting clot formation or preventing existing clots from enlarging. While highly beneficial, their use requires careful monitoring to minimize the risk of bleeding complications.
