Anticoagulants


Anticoagulants are a vital category of pharmaceutical active pharmaceutical ingredients (APIs) used to prevent and treat blood clotting disorders. These medications play a crucial role in various medical conditions, including deep vein thrombosis (DVT), pulmonary embolism (PE), and atrial fibrillation (AF). Anticoagulants work by inhibiting the formation of blood clots or by preventing existing clots from getting larger.

There are different types of anticoagulants available, including direct thrombin inhibitors, vitamin K antagonists, and factor Xa inhibitors. Direct thrombin inhibitors, such as dabigatran, directly target the enzyme thrombin to hinder clot formation. Vitamin K antagonists, like warfarin, interfere with the production of clotting factors that rely on vitamin K. Factor Xa inhibitors, such as rivaroxaban and apixaban, inhibit the activity of factor Xa, a crucial component in the clotting cascade.

Anticoagulants are commonly prescribed to patients at risk of developing blood clots or those with existing clotting disorders. They are often used during surgeries, such as hip or knee replacements, to minimize the risk of post-operative clot formation. Patients with AF, a condition characterized by irregular heart rhythm, may also be prescribed anticoagulants to prevent stroke caused by blood clots.

While anticoagulants offer significant benefits in preventing and treating clot-related conditions, they also carry potential risks, including bleeding complications. Patients taking anticoagulants require careful monitoring to ensure the right dosage is administered, as excessive anticoagulation can lead to hemorrhage. Regular blood tests and close medical supervision are essential to manage the delicate balance between preventing clots and avoiding excessive bleeding.

In conclusion, anticoagulants are a crucial category of pharmaceutical APIs used to prevent and treat blood clotting disorders. They function by inhibiting clot formation or preventing existing clots from enlarging. While highly beneficial, their use requires careful monitoring to minimize the risk of bleeding complications.

NameCAS numberCategoryAmount of suppliersAPI market price
1-Methoxydecane1120-21-4AntithromboticsView 1 Suppliers Average price per kg: $
Abciximab143653-53-6Glycoprotein IIb/IIIa receptor antagonistsView 1 Suppliers Average price per kg: $
Acenocoumarol152-72-7Other antithrombinView 7 Suppliers Average price per kg: $
Acetazolamide59-66-5Carbonic anhydrase(II) inhibitorsView 13 Suppliers Average price per kg: $
Aesculin66778-17-4Anticoagulant proteinsView 2 Suppliers Average price per kg: $
Apixaban503612-47-3AntithromboticsView 63 Suppliers Average price per kg: $
Argatroban74863-84-6Anticoagulant proteinsView 16 Suppliers Average price per kg: $
Astaxanthin472-61-7AnticoagulantsView 2 Suppliers Average price per kg: $
Betrixaban330942-05-7AnticoagulantsView 0 Suppliers Average price per kg: $
Bivalirudin128270-60-0AntithromboticsView 21 Suppliers Average price per kg: $
Calaspargase pegol941577-06-6AnticoagulantsView 0 Suppliers Average price per kg: $
Cangrelor163706-06-7AntithromboticsView 3 Suppliers Average price per kg: $
Carbazochrome sulfonic acid70063-04-6AnticoagulantsView 0 Suppliers Average price per kg: $
Cilengitide188968-51-6Other antithrombinView 1 Suppliers Average price per kg: $
Cilostazol73963-72-1AntithromboticsView 26 Suppliers Average price per kg: $
Cinnamic acid140-10-3AnticoagulantsView 0 Suppliers Average price per kg: $
Clorindione1146-99-2AnticoagulantsView 0 Suppliers Average price per kg: $
Coumarin91-64-5AnticoagulantsView 0 Suppliers Average price per kg: $
Dabigatran211914-51-1AnticoagulantsView 1 Suppliers Average price per kg: $
Dabigatran etexilate211915-06-9Direct thrombin inhibitorsView 43 Suppliers Average price per kg: $
Dalteparin9005-49-6HeparinsView 6 Suppliers Average price per kg: $
Danaparoid308068-55-5AnticoagulantsView 0 Suppliers Average price per kg: $
Dermatan sulfate24967-94-0AnticoagulantsView 0 Suppliers Average price per kg: $
Diphenadione82-66-6AnticoagulantsView 0 Suppliers Average price per kg: $
Dociparstat sodium177021-00-0AnticoagulantsView 0 Suppliers Average price per kg: $
Dorzolamide120279-96-1Carbonic anhydrase(II) inhibitorsView 26 Suppliers Average price per kg: $
Edoxaban480449-70-5AntithromboticsView 17 Suppliers Average price per kg: $
Eltrombopag496775-61-2Other antithrombinView 10 Suppliers Average price per kg: $
Enoxaparin9005-49-6HeparinsView 22 Suppliers Average price per kg: $
Eptifibatide188627-80-7Glycoprotein IIb/IIIa receptor antagonistsView 23 Suppliers Average price per kg: $
Fluindione957-56-2Anticoagulant proteinsView 2 Suppliers Average price per kg: $
Fondaparinux sodium114870-03-0AntithromboticsView 15 Suppliers Average price per kg: $
Gabexate39492-01-8AnticoagulantsView 0 Suppliers Average price per kg: $
Heparin calcium37270-89-6Anticoagulant proteinsView 10 Suppliers Average price per kg: $
Heparin sodium9005-49-6Anticoagulant proteinsView 43 Suppliers Average price per kg: $
HeparinoidAnticoagulant proteinsView 1 Suppliers Average price per kg: $
Idraparinux162610-17-5AnticoagulantsView 0 Suppliers Average price per kg: $
Kappadione131-13-5Anticoagulant proteinsView 1 Suppliers Average price per kg: $
Lepirudin138068-37-8Direct thrombin inhibitorsView 2 Suppliers Average price per kg: $
Letaxaban870262-90-1AnticoagulantsView 0 Suppliers Average price per kg: $
Menaquinone1182-68-9AnticoagulantsView 0 Suppliers Average price per kg: $
Menaquinone 684-81-1AnticoagulantsView 0 Suppliers Average price per kg: $
Menaquinone 72124-57-4AnticoagulantsView 0 Suppliers Average price per kg: $
Methazolamide554-57-4Carbonic anhydrase(II) inhibitorsView 6 Suppliers Average price per kg: $
Nadroparin9041-08-1HeparinsView 4 Suppliers Average price per kg: $
Parnaparin91449-79-5HeparinsView 3 Suppliers Average price per kg: $
Phenprocoumon435-97-2Other antithrombinView 3 Suppliers Average price per kg: $
Potassium triiodide12298-68-9AnticoagulantsView 0 Suppliers Average price per kg: $
Prasugrel150322-43-3AntithromboticsView 26 Suppliers Average price per kg: $
Protocatechualdehyde139-85-5AnticoagulantsView 0 Suppliers Average price per kg: $
Rivaroxaban366789-02-8AntithromboticsView 78 Suppliers Average price per kg: $
Romiplostim267639-76-9Other antithrombinView 1 Suppliers Average price per kg: $
SG31991595275-71-0Other antithrombinView 2 Suppliers Average price per kg: $
Sodium Citrate68-04-2Anticoagulant proteinsView 13 Suppliers Average price per kg: $
Streptokinase9002-01-1ThrombolyticsView 1 Suppliers Average price per kg: $
Sulodexide57821-29-1AntithromboticsView 4 Suppliers Average price per kg: $
Tenecteplase191588-94-0ThrombolyticsView 1 Suppliers Average price per kg: $
Tioclomarol22619-35-8AnticoagulantsView 0 Suppliers Average price per kg: $
Tirofiban144494-65-5Glycoprotein IIb/IIIa receptor antagonistsView 8 Suppliers Average price per kg: $
Tocopherylquinone7559-04-8AnticoagulantsView 0 Suppliers Average price per kg: $
Urokinase9039-53-6ThrombolyticsView 1 Suppliers Average price per kg: $
Vorapaxar618385-01-6Other antithrombinView 1 Suppliers Average price per kg: $
Warfarin81-81-2Other anticoagulantsView 22 Suppliers Average price per kg: $