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Looking for Menaquinone API 1182-68-9?

Description:
Here you will find a list of producers, manufacturers and distributors of Menaquinone. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Menaquinone 
Synonyms:
 
Cas Number:
1182-68-9 
DrugBank number:
DB15381 
Unique Ingredient Identifier:
12V8PA4WCH

General Description:

Menaquinone, identified by CAS number 1182-68-9, is a notable compound with significant therapeutic applications. Menaquinone is under investigation in clinical trial NCT01533441 (Vitamin K2 Intervention in Patients With Vitamin K Antagonists).

Categories:

Menaquinone is categorized under the following therapeutic classes: Coagulants, Diet, Food, and Nutrition, Diterpenes, Fibrin Modulating Agents, Food, Hematologic Agents, Hemostatics, Micronutrients, Naphthalenes, Naphthoquinones, Physiological Phenomena, Phytol, Quinones, Terpenes, Vitamin K, Vitamin K 2, Vitamins, Vitamins (Fat Soluble). These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.

Menaquinone is a type of Anticoagulants


Anticoagulants are a vital category of pharmaceutical active pharmaceutical ingredients (APIs) used to prevent and treat blood clotting disorders. These medications play a crucial role in various medical conditions, including deep vein thrombosis (DVT), pulmonary embolism (PE), and atrial fibrillation (AF). Anticoagulants work by inhibiting the formation of blood clots or by preventing existing clots from getting larger.

There are different types of anticoagulants available, including direct thrombin inhibitors, vitamin K antagonists, and factor Xa inhibitors. Direct thrombin inhibitors, such as dabigatran, directly target the enzyme thrombin to hinder clot formation. Vitamin K antagonists, like warfarin, interfere with the production of clotting factors that rely on vitamin K. Factor Xa inhibitors, such as rivaroxaban and apixaban, inhibit the activity of factor Xa, a crucial component in the clotting cascade.

Anticoagulants are commonly prescribed to patients at risk of developing blood clots or those with existing clotting disorders. They are often used during surgeries, such as hip or knee replacements, to minimize the risk of post-operative clot formation. Patients with AF, a condition characterized by irregular heart rhythm, may also be prescribed anticoagulants to prevent stroke caused by blood clots.

While anticoagulants offer significant benefits in preventing and treating clot-related conditions, they also carry potential risks, including bleeding complications. Patients taking anticoagulants require careful monitoring to ensure the right dosage is administered, as excessive anticoagulation can lead to hemorrhage. Regular blood tests and close medical supervision are essential to manage the delicate balance between preventing clots and avoiding excessive bleeding.

In conclusion, anticoagulants are a crucial category of pharmaceutical APIs used to prevent and treat blood clotting disorders. They function by inhibiting clot formation or preventing existing clots from enlarging. While highly beneficial, their use requires careful monitoring to minimize the risk of bleeding complications.