St. John's Wort API Manufacturers

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Looking for St. John's Wort API 84082-80-4?

Description:
Here you will find a list of producers, manufacturers and distributors of St. John's Wort. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
St. John's Wort 
Synonyms:
Common st johnswort flowering top , Common st. john's wort flowering top , Common st. john's wort herb , Common st. johnswort flowering top , Guanyejinsitao , Hyperici herba , Hypericum nachitschevanicum flowering top , Hypericum perforatum flowering top , Hypoxis hemerocallidea root extract , Klamath weed flowering top , Klamathweed flowering top , Saint johns wort , St john's wort , St Johns Wort , St. john’s wort , St. johns wort , St. johnswort flowering top  
Cas Number:
84082-80-4 
DrugBank number:
DB01323 
Unique Ingredient Identifier:
UFH8805FKA

General Description:

St. John's Wort is a chemical compound identified by the CAS number 84082-80-4. It is known for its distinct pharmacological properties and applications.

Categories:

St. John's Wort is categorized under the following therapeutic classes: Angiosperms, Antidepressive Agents, Antidepressive Agents Indicated for Depression, Biological Products, Central Nervous System Depressants, Clusiaceae, Complex Mixtures, Cytochrome P-450 CYP2C19 Inducers, Cytochrome P-450 CYP2C19 Inducers (strength unknown), Cytochrome P-450 CYP2C19 Substrates, Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 CYP2D6 Inhibitors (weak), Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A Inducers (strong), Cytochrome P-450 CYP3A Substrates, Cytochrome P-450 CYP3A4 Inducers, Cytochrome P-450 CYP3A4 Inducers (strong), Cytochrome P-450 CYP3A4 Substrates, Cytochrome P-450 CYP3A4 Substrates (strength unknown), Cytochrome P-450 Enzyme Inducers, Cytochrome P-450 Enzyme Inhibitors, Cytochrome P-450 Substrates, Embryophyta, Eukaryota, Herbs and Natural Products, Hyperglycemia-Associated Agents, Nervous System, P-glycoprotein inducers, Pharmaceutical Preparations, Plant Preparations, Psychoanaleptics, Rosanae, Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Streptophyta, Tracheophyta, Viridiplantae. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.

St. John's Wort is a type of Antidepressants


Antidepressants are a category of pharmaceutical Active Pharmaceutical Ingredients (APIs) widely used in the treatment of depression and other mood disorders. These medications work by balancing the levels of certain chemicals in the brain called neurotransmitters, such as serotonin, norepinephrine, and dopamine.

There are several types of antidepressants available, each with its own mechanism of action and efficacy. Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed as a first-line treatment for depression. They prevent the reabsorption of serotonin, resulting in increased serotonin levels in the brain. Examples of popular SSRIs include fluoxetine, sertraline, and escitalopram.

Tricyclic antidepressants (TCAs) are another class of antidepressants that work by blocking the reuptake of both serotonin and norepinephrine. They are generally used when SSRIs are ineffective or not well-tolerated. Amitriptyline, nortriptyline, and imipramine are commonly prescribed TCAs.

Other antidepressants include serotonin-norepinephrine reuptake inhibitors (SNRIs), atypical antidepressants, and monoamine oxidase inhibitors (MAOIs). SNRIs, such as venlafaxine and duloxetine, inhibit the reuptake of both serotonin and norepinephrine. Atypical antidepressants, including bupropion and mirtazapine, have diverse mechanisms of action, targeting multiple neurotransmitters. MAOIs, such as phenelzine and tranylcypromine, work by inhibiting the enzyme monoamine oxidase, which breaks down neurotransmitters.

It is important to note that antidepressants may have various side effects and require close monitoring by healthcare professionals. Dosages and treatment duration vary based on individual needs and response. Antidepressants are typically prescribed as part of a comprehensive treatment plan that may include psychotherapy and lifestyle modifications.

In conclusion, antidepressants are a vital category of pharmaceutical APIs used to manage depression and related mood disorders. They act on neurotransmitters in the brain to alleviate symptoms and improve overall well-being. It is crucial to consult with a healthcare provider to determine the most suitable antidepressant and monitor its effects.