Antidepressants


Antidepressants are a category of pharmaceutical Active Pharmaceutical Ingredients (APIs) widely used in the treatment of depression and other mood disorders. These medications work by balancing the levels of certain chemicals in the brain called neurotransmitters, such as serotonin, norepinephrine, and dopamine.

There are several types of antidepressants available, each with its own mechanism of action and efficacy. Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed as a first-line treatment for depression. They prevent the reabsorption of serotonin, resulting in increased serotonin levels in the brain. Examples of popular SSRIs include fluoxetine, sertraline, and escitalopram.

Tricyclic antidepressants (TCAs) are another class of antidepressants that work by blocking the reuptake of both serotonin and norepinephrine. They are generally used when SSRIs are ineffective or not well-tolerated. Amitriptyline, nortriptyline, and imipramine are commonly prescribed TCAs.

Other antidepressants include serotonin-norepinephrine reuptake inhibitors (SNRIs), atypical antidepressants, and monoamine oxidase inhibitors (MAOIs). SNRIs, such as venlafaxine and duloxetine, inhibit the reuptake of both serotonin and norepinephrine. Atypical antidepressants, including bupropion and mirtazapine, have diverse mechanisms of action, targeting multiple neurotransmitters. MAOIs, such as phenelzine and tranylcypromine, work by inhibiting the enzyme monoamine oxidase, which breaks down neurotransmitters.

It is important to note that antidepressants may have various side effects and require close monitoring by healthcare professionals. Dosages and treatment duration vary based on individual needs and response. Antidepressants are typically prescribed as part of a comprehensive treatment plan that may include psychotherapy and lifestyle modifications.

In conclusion, antidepressants are a vital category of pharmaceutical APIs used to manage depression and related mood disorders. They act on neurotransmitters in the brain to alleviate symptoms and improve overall well-being. It is crucial to consult with a healthcare provider to determine the most suitable antidepressant and monitor its effects.

NameCAS numberCategoryAmount of suppliersAPI market price
3,7-Dichloroimipramine Hydrochloride577-11-7Tricyclic antidepressantsView 1 Suppliers Average price per kg: $
Agomelatine138112-76-2AntidepressantsView 19 Suppliers Average price per kg: $
Amitriptyline50-48-6Tricyclic antidepressantsView 17 Suppliers Average price per kg: $
Amoxapine14028-44-5Tricyclic antidepressantsView 3 Suppliers Average price per kg: $
Basimglurant802906-73-6AntidepressantsView 0 Suppliers Average price per kg: $
Bifemelane90293-01-9AntidepressantsView 0 Suppliers Average price per kg: $
Bupropion34911-55-2AntidepressantsView 28 Suppliers Average price per kg: $
Chlorophyll B519-62-0AntidepressantsView 0 Suppliers Average price per kg: $
Clomipramine303-49-1Tricyclic antidepressantsView 15 Suppliers Average price per kg: $
Cyclocreatine35404-50-3AntidepressantsView 0 Suppliers Average price per kg: $
Dasotraline675126-05-3AntidepressantsView 0 Suppliers Average price per kg: $
Dehydroclomipramine HydrochlorideTricyclic antidepressantsView 1 Suppliers Average price per kg: $
Desipramine50-47-5Tricyclic antidepressantsView 3 Suppliers Average price per kg: $
Desvenlafaxine93413-62-8Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs)View 19 Suppliers Average price per kg: $
Dexmecamylamine107538-05-6AntidepressantsView 0 Suppliers Average price per kg: $
Dosulepin113-53-1Tricyclic antidepressantsView 1 Suppliers Average price per kg: $
Doxepin1668-19-5Tricyclic antidepressantsView 5 Suppliers Average price per kg: $
Duloxetine116539-59-4Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs)View 54 Suppliers Average price per kg: $
Farampator211735-76-1AntidepressantsView 0 Suppliers Average price per kg: $
Imipramine50-49-7Tricyclic antidepressantsView 9 Suppliers Average price per kg: $
Imipramine oxide6829-98-7AntidepressantsView 0 Suppliers Average price per kg: $
Intermedine581-05-5AntidepressantsView 0 Suppliers Average price per kg: $
Iprindole5560-72-5AntidepressantsView 0 Suppliers Average price per kg: $
Ispectamab debotansine2413386-21-5AntidepressantsView 0 Suppliers Average price per kg: $
Lauric acid143-07-7AntidepressantsView 0 Suppliers Average price per kg: $
Levomilnacipran96847-54-0Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs)View 12 Suppliers Average price per kg: $
Lithium citrate919-16-4AntidepressantsView 0 Suppliers Average price per kg: $
Lofepramine23047-25-8AntidepressantsView 0 Suppliers Average price per kg: $
Malic acid6915-15-7AntidepressantsView 0 Suppliers Average price per kg: $
Maprotiline10262-69-8Tricyclic antidepressantsView 2 Suppliers Average price per kg: $
Medifoxamine32359-34-5AntidepressantsView 0 Suppliers Average price per kg: $
Melitracen5118-29-6AntidepressantsView 0 Suppliers Average price per kg: $
Milnacipran92623-85-3Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs)View 19 Suppliers Average price per kg: $
Mirtazapine85650-52-8AntidepressantsView 22 Suppliers Average price per kg: $
Moclobemide71320-77-9AntidepressantsView 4 Suppliers Average price per kg: $
Nortriptyline72-69-5Tricyclic antidepressantsView 10 Suppliers Average price per kg: $
Opipramol315-72-0AntidepressantsView 0 Suppliers Average price per kg: $
Opipramol DiHydrochlorideTricyclic antidepressantsView 5 Suppliers Average price per kg: $
Opipramol DiHydrochlorideTricyclic antidepressantsView 5 Suppliers Average price per kg: $
Oxaflozane26629-87-8AntidepressantsView 0 Suppliers Average price per kg: $
Protriptyline438-60-8AntidepressantsView 3 Suppliers Average price per kg: $
Quinupramine31721-17-2AntidepressantsView 0 Suppliers Average price per kg: $
Saredutant142001-63-6AntidepressantsView 0 Suppliers Average price per kg: $
St. John's Wort84082-80-4AntidepressantsView 0 Suppliers Average price per kg: $
Tesofensine195875-84-4AntidepressantsView 0 Suppliers Average price per kg: $
Tianeptine sodium72797-41-2AntidepressantsView 6 Suppliers Average price per kg: $
Tianeptine sulfate1224690-84-9AntidepressantsView 1 Suppliers Average price per kg: $
Trimipramine739-71-9Tricyclic antidepressantsView 3 Suppliers Average price per kg: $
Tusamitamab ravtansine2254086-60-5AntidepressantsView 0 Suppliers Average price per kg: $
Venlafaxine93413-69-5Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs)View 54 Suppliers Average price per kg: $