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Vofopitant
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Looking for Vofopitant API 168266-90-8?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Vofopitant. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Vofopitant
- Synonyms:
- Cas Number:
- 168266-90-8
- DrugBank number:
- DB12436
- Unique Ingredient Identifier:
- K08BK043YS
General Description:
Vofopitant, identified by CAS number 168266-90-8, is a notable compound with significant therapeutic applications. Vofopitant has been used in trials studying the treatment of PTSD, Primary Insomnia, and Sleep Initiation and Maintenance Disorders.
Classification:
Vofopitant belongs to the class of organic compounds known as phenylpiperidines. These are compounds containing a phenylpiperidine skeleton, which consists of a piperidine bound to a phenyl group, classified under the direct parent group Phenylpiperidines. This compound is a part of the Organic compounds, falling under the Organoheterocyclic compounds superclass, and categorized within the Piperidines class, specifically within the Phenylpiperidines subclass.
Categories:
Vofopitant is categorized under the following therapeutic classes: Antiemetics, Autonomic Agents, Central Nervous System Agents, Gastrointestinal Agents, Neurokinin-1 Receptor Antagonists, Neurotransmitter Agents, Peripheral Nervous System Agents. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Vofopitant is a type of Antiemetics
Antiemetics are a crucial category of pharmaceutical Active Pharmaceutical Ingredients (APIs) used to alleviate and prevent nausea and vomiting, also known as emesis. They play a vital role in managing these distressing symptoms, which can be caused by various factors such as chemotherapy, postoperative recovery, motion sickness, or gastrointestinal disorders.
Antiemetics work by targeting specific pathways in the body that trigger emesis. One common mechanism involves blocking dopamine receptors in the brain, as dopamine plays a significant role in triggering the vomiting reflex. This class of antiemetics is known as dopamine antagonists. Another mechanism involves inhibiting serotonin receptors, which are associated with nausea and vomiting. These agents, called serotonin antagonists, effectively reduce these symptoms.
In addition to dopamine and serotonin antagonists, other types of antiemetics include neurokinin-1 receptor antagonists, antihistamines, and anticholinergics. Each of these classes acts on different pathways in the body to provide relief from nausea and vomiting.
Pharmaceutical companies manufacture antiemetic APIs in accordance with strict quality control guidelines and regulations. These APIs serve as the active ingredients in various formulations, such as tablets, capsules, injections, or suppositories, designed to deliver the desired therapeutic effects.
Overall, antiemetic APIs form an essential category in the pharmaceutical industry, addressing the significant need for effective management of nausea and vomiting. Their development and availability greatly contribute to enhancing patient comfort and quality of life during various medical treatments and conditions.
