Pirfenidone API Manufacturers

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Located in:

India

Produced in:

India

Established in: 1989

MOQ: -

Employees: 5000+

6 production facilities approved by USFDA, AGES-Austria, PMDA, WHO

R&D Centers with capabilities of ANDAs, DMFs and NDDS

462+ patents filed for drug substances and polymorphs

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Produced in:

China

Established in: 2011

MOQ: 1 kg

Employees: 10+

Fast Response and Good Communication

Willingness To Start From Small

Flexible Payment Terms

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Produced in:

Unknown

Established in: 1963

MOQ: -

Employees: 800+

World’s 1st exclusive API distributor

Portfolio of 600+ APIs

>250 clients in Europe

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Located in:

China

Produced in:

China

MOQ: -

Established for 17 years and a leading enterprise in China's API industry

Mature technology and advanced production equipment

Quality assurance and fast delivery

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Located in:

Spain

Produced in:

Spain

MOQ: -

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Located in:

Spain

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Spain

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India

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India

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Mexico

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Produced in:

Mexico

MOQ: -

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India

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India

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India

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India

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India

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India

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Located in:

Italy

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Italy

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Located in:

India

Produced in:

India

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Germany

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India

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India

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Located in:

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India

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India

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India

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India

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India

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Located in:

India

Produced in:

India

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Located in:

India

Produced in:

India

MOQ: -

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Located in:

India

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Produced in:

India

MOQ: -

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Looking for Pirfenidone API 53179-13-8?

Description:
Here you will find a list of producers, manufacturers and distributors of Pirfenidone. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Pirfenidone 
Synonyms:
 
Cas Number:
53179-13-8 
DrugBank number:
DB04951 
Unique Ingredient Identifier:
D7NLD2JX7U

About Pirfenidone

So, what does it do? Pirfenidone is an orally active small molecule drug that may inhibit collagen synthesis, down regulate production of multiple cytokines and block fibroblast proliferation and stimulation in response to cytokines. Pirfenidone has demonstrated activity in multiple fibrotic conditions, including those of the lung, kidney and liver. It is being investigated by InterMune.

Not sure if this is the exact product you're looking for? Contact the supplier by using the send inquiry button.

Pirfenidone is a type of Antifibrotic agents


Antifibrotic agents belong to the pharmaceutical API category that focuses on treating fibrosis, a condition characterized by the excessive accumulation of fibrous connective tissue in organs. These agents target the underlying mechanisms involved in fibrosis and help prevent or slow down the progression of the disease.

One commonly used antifibrotic agent is Pirfenidone, which has shown efficacy in treating idiopathic pulmonary fibrosis (IPF). It works by inhibiting the production of pro-inflammatory and fibrotic factors, such as transforming growth factor-beta (TGF-β), platelet-derived growth factor (PDGF), and fibroblast growth factor (FGF). By reducing the levels of these factors, Pirfenidone helps suppress the proliferation and activation of fibroblasts, which are responsible for excessive collagen deposition in fibrotic tissues.

Another antifibrotic agent, Nintedanib, also targets IPF. It is a tyrosine kinase inhibitor that blocks the activity of various growth factor receptors, including PDGF, fibroblast growth factor receptor (FGFR), and vascular endothelial growth factor receptor (VEGFR). By inhibiting these receptors, Nintedanib disrupts the signaling pathways involved in fibrosis, thereby reducing fibroblast activation and collagen production.

These antifibrotic agents have shown promising results in clinical trials and have been approved for the treatment of IPF in several countries. They represent a significant advancement in the management of fibrotic diseases and offer hope to patients by slowing down disease progression and improving overall outcomes.

In conclusion, antifibrotic agents are a vital category of pharmaceutical APIs that target the underlying mechanisms of fibrosis. Through their action on key molecular pathways involved in fibrotic tissue deposition, these agents help reduce the accumulation of fibrous connective tissue and provide potential therapeutic benefits for patients with fibrotic diseases.

Pirfenidone manufacturers | traders | suppliers

We have 23 companies offering Pirfenidone produced in 6 different countries.

Get in contact with the supplier of your choice:

  • Shilpa Medicare Ltd from India, product country of origin India
  • Shandong Octagon Chemicals Limited from China, product country of origin China
  • TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
  • Xi'an ZB Biotech Co., Ltd from China, product country of origin China
  • Chemo Iberica from Spain, product country of origin Spain
  • Rolabo Outsourcing from Spain, product country of origin Spain
  • Raks Pharma from India, product country of origin India
  • Signa from Mexico, product country of origin Mexico
  • Laurus Labs from India, product country of origin India
  • Chemeca Drugs pvt Ltd from India, product country of origin India
  • Honour Lab from India, product country of origin India
  • Procos from Italy, product country of origin Italy
  • ZCL Chemicals from India, product country of origin India
  • Jubilant Generics from India, product country of origin India
  • Pharmazell from Germany, product country of origin India
  • MSN Pharma from India, product country of origin India
  • Mylan from India, product country of origin India
  • MSN Life Sciences from India, product country of origin India
  • Micro Labs from India, product country of origin India
  • Cipla from India, product country of origin India
  • Granules India from India, product country of origin India
  • Optimus Drugs Pvt Ltd from India, product country of origin India
  • Lupin from India, product country of origin India

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