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Pirfenidone
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Producer
Produced in:
Established in: 1989
MOQ: -
Employees: 5000+
6 production facilities approved by USFDA, AGES-Austria, PMDA, WHO
R&D Centers with capabilities of ANDAs, DMFs and NDDS
462+ patents filed for drug substances and polymorphs
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Producer
Produced in:
Established in: 1978
MOQ: -
Employees: 10k+
199 API-Related Granted Patents
Global Presence in 50+ Markets
Advanced technology and R&D Capabilities
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Producer
Produced in:
Established in: 2013
MOQ: 1 g
Employees: 25+
ISO9001 certified
Drug R&D center (in Hangzhou)
From lab scale (mg/g) to commercial scale (kgs/tons)
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Producer
Established for 17 years and a leading enterprise in China's API industry
Mature technology and advanced production equipment
Quality assurance and fast delivery
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Distributor
Produced in:
Established in: 1987
MOQ: 1 kg
Employees: 50+
ISO 9001:2015 & SGS audited supplier
One-stop CDMO Solutions for APl and Key intermediates
Specialized in APIs & Pharmaceutical Intermediates for 37 years
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Distributor
Produced in:
Established in: 2011
MOQ: 1 kg
Employees: 10+
Fast Response and Good Communication
Willingness To Start From Small
Flexible Payment Terms
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Producer
Produced in:
Established in: 2021
MOQ: -
Employees: 19
API, Intermediates, Building Blocks, Impurities, Amino acids and Peptides
Small quantity APIs to commercial scale
GMP and USFDA certification based on quantity, order, assignment.
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Distributor
Produced in:
Established in: 1963
MOQ: -
Employees: 800+
World’s 1st exclusive API distributor
Portfolio of 600+ APIs
>250 clients in Europe
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Looking for Pirfenidone API 53179-13-8?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Pirfenidone. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Pirfenidone
- Cas Number:
- 53179-13-8
- DrugBank number:
- DB04951
- Unique Ingredient Identifier:
- D7NLD2JX7U
About Pirfenidone
So, what does it do? Pirfenidone is an orally active small molecule drug that may inhibit collagen synthesis, down regulate production of multiple cytokines and block fibroblast proliferation and stimulation in response to cytokines. Pirfenidone has demonstrated activity in multiple fibrotic conditions, including those of the lung, kidney and liver. It is being investigated by InterMune.
Not sure if this is the exact product you're looking for? Contact the supplier by using the send inquiry button.
Pirfenidone is a type of Antifibrotic agents
Antifibrotic agents belong to the pharmaceutical API category that focuses on treating fibrosis, a condition characterized by the excessive accumulation of fibrous connective tissue in organs. These agents target the underlying mechanisms involved in fibrosis and help prevent or slow down the progression of the disease.
One commonly used antifibrotic agent is Pirfenidone, which has shown efficacy in treating idiopathic pulmonary fibrosis (IPF). It works by inhibiting the production of pro-inflammatory and fibrotic factors, such as transforming growth factor-beta (TGF-β), platelet-derived growth factor (PDGF), and fibroblast growth factor (FGF). By reducing the levels of these factors, Pirfenidone helps suppress the proliferation and activation of fibroblasts, which are responsible for excessive collagen deposition in fibrotic tissues.
Another antifibrotic agent, Nintedanib, also targets IPF. It is a tyrosine kinase inhibitor that blocks the activity of various growth factor receptors, including PDGF, fibroblast growth factor receptor (FGFR), and vascular endothelial growth factor receptor (VEGFR). By inhibiting these receptors, Nintedanib disrupts the signaling pathways involved in fibrosis, thereby reducing fibroblast activation and collagen production.
These antifibrotic agents have shown promising results in clinical trials and have been approved for the treatment of IPF in several countries. They represent a significant advancement in the management of fibrotic diseases and offer hope to patients by slowing down disease progression and improving overall outcomes.
In conclusion, antifibrotic agents are a vital category of pharmaceutical APIs that target the underlying mechanisms of fibrosis. Through their action on key molecular pathways involved in fibrotic tissue deposition, these agents help reduce the accumulation of fibrous connective tissue and provide potential therapeutic benefits for patients with fibrotic diseases.
Pirfenidone manufacturers | traders | suppliers
We have 24 companies offering Pirfenidone produced in 6 different countries.
Get in contact with the supplier of your choice:
- Shilpa Medicare Ltd from India, product country of origin India
- Jubilant Pharmova from India, product country of origin India
- Senova Technology Co., Ltd. from China, product country of origin China
- Xi'an ZB Biotech Co., Ltd from China, product country of origin China
- Sinoway industrial Co.,Ltd from China, product country of origin China
- Shandong Octagon Chemicals Limited from China, product country of origin China
- SETV Global from India, product country of origin India
- Laurus Labs from India, product country of origin India
- Raks Pharma from India, product country of origin India
- Chemeca Drugs pvt Ltd from India, product country of origin India
- Rolabo Outsourcing from Spain, product country of origin Spain
- Chemo Iberica from Spain, product country of origin Spain
- Signa from Mexico, product country of origin Mexico
- Honour Lab from India, product country of origin India
- TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
- Micro Labs from India, product country of origin India
- ZCL Chemicals from India, product country of origin India
- Cipla from India, product country of origin India
- Procos from Italy, product country of origin Italy
- Optimus Drugs Pvt Ltd from India, product country of origin India
- MSN Pharma from India, product country of origin India
- Mylan from India, product country of origin India
- Lupin from India, product country of origin India
- MSN Life Sciences from India, product country of origin India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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