Metergoline API Manufacturers
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Looking for Metergoline API 17692-51-2?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Metergoline. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Metergoline
- Synonyms:
- Metergolina , Metergolinum
- Cas Number:
- 17692-51-2
- DrugBank number:
- DB13520
- Unique Ingredient Identifier:
- 1501393LY5
General Description:
Metergoline, identified by CAS number 17692-51-2, is a notable compound with significant therapeutic applications. Metergoline is an ergot-derived psychoactive drug that acts as a ligand for serotonin and dopamine receptors. Metergoline is an antagonist at various 5-HT receptor subtypes at a relatively low concentration and agonist at dopamine receptors. Its use has been studied in various clinical settings such as a treatment for seasonal affective disorder, prolactin hormone regulation due to its inhibitory effect on prolactin release, premenstrual dysphoric disorder in women and antianxiety treatment.
Classification:
Metergoline belongs to the class of organic compounds known as indoloquinolines. These are polycyclic aromatic compounds containing an indole fused to a quinoline, classified under the direct parent group Indoloquinolines. This compound is a part of the Organic compounds, falling under the Organoheterocyclic compounds superclass, and categorized within the Quinolines and derivatives class, specifically within the Indoloquinolines subclass.
Categories:
Metergoline is categorized under the following therapeutic classes: Agents that produce hypertension, Alkaloids, Antidepressive Agents, Central Nervous System Depressants, Dopamine Agents, Dopamine Agonists, Ergolines, Ergot Alkaloids and Derivatives, Ergot-derivative Dopamine Receptor Agonists, Genito Urinary System and Sex Hormones, Heterocyclic Compounds, Fused-Ring, Neurotransmitter Agents, Prolactine Inhibitors, Serotonin Agents, Serotonin Receptor Agonists, Serotonin Receptor Antagonists. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Metergoline is a type of Antihypertensive agents
Antihypertensive agents are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) used to treat high blood pressure, also known as hypertension. These medications are designed to lower blood pressure and reduce the risk of associated cardiovascular complications.
Antihypertensive agents function by targeting various mechanisms involved in blood pressure regulation. Some common classes of antihypertensive agents include angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), beta-blockers, calcium channel blockers (CCBs), and diuretics.
ACE inhibitors work by inhibiting the enzyme responsible for converting angiotensin I to angiotensin II, a hormone that constricts blood vessels. ARBs, on the other hand, block the receptors to which angiotensin II binds, thereby preventing its vasoconstrictive effects.
Beta-blockers reduce blood pressure by blocking the effects of adrenaline and noradrenaline, which are responsible for increasing heart rate and constricting blood vessels. CCBs inhibit calcium from entering the smooth muscles of blood vessels, resulting in relaxation and vasodilation. Diuretics promote the elimination of excess fluid and sodium from the body, reducing blood volume and thereby lowering blood pressure.
Antihypertensive agents are typically prescribed based on the individual patient's condition and specific needs. They can be used alone or in combination to achieve optimal blood pressure control. It is important to note that antihypertensive agents should be taken regularly as prescribed by a healthcare professional and may require periodic monitoring to ensure their effectiveness and manage any potential side effects.
In summary, antihypertensive agents play a vital role in the management of hypertension by targeting various mechanisms involved in blood pressure regulation. These medications offer significant benefits in reducing the risk of cardiovascular complications associated with high blood pressure.
