Capecitabine
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Produced in:
Established in: 1989
MOQ: -
Employees: 5000+

6 production facilities approved by USFDA, AGES-Austria, PMDA, WHO

R&D Centers with capabilities of ANDAs, DMFs and NDDS

462+ patents filed for drug substances and polymorphs
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Established in: 2012
MOQ: 1 kg
Employees: 50+

Diverse portfolio of APIs and Nutra products

Focus on Hormones Oncology and Peptides with the highest quality

Leading manufacturer of ALpha Lipoic Acid
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Produced in:
Established in: 2013
MOQ: 1 kg
Employees: 25+

ISO9001 certified

Drug R&D center (in Hangzhou)

From lab scale (mg/g) to commercial scale (kgs/tons)
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Produced in:

Established in: 1963
MOQ: -
Employees: 800+

World’s 1st exclusive API distributor

Portfolio of 600+ APIs

>250 clients in Europe
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Looking for Capecitabine 154361-50-9?
- Description:
- Here you will find a list of producers, manufacturers and traders of Capecitabine. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Capecitabine
- Synonyms:
- Capecitabin , Capecitabina , Capecitabinum , Xeloda
- Cas Number:
- 154361-50-9
- DrugBank number:
- DB01101
- Unique Ingredient Identifier:
- 6804DJ8Z9U
About Capecitabine
Here, you can find what Capecitabine is used for, in short. Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. Capecitabine is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue.
More information such as the structure, indication or toxicity is available on Drugbank, click the ID above.
Capecitabine is a type of Antimetabolites
Antimetabolites are a prominent category of pharmaceutical active pharmaceutical ingredients (APIs) utilized in the treatment of various diseases, particularly cancer. These compounds are structurally similar to naturally occurring metabolites essential for cellular processes such as DNA and RNA synthesis. By mimicking these metabolites, antimetabolites interfere with the normal functioning of cellular pathways, leading to inhibition of cancer cell growth and proliferation.
One of the widely used antimetabolites is methotrexate, a folic acid antagonist that inhibits the enzyme dihydrofolate reductase, disrupting the production of DNA and RNA. This disruption impedes the growth of rapidly dividing cancer cells. Another common antimetabolite is 5-fluorouracil (5-FU), which inhibits the enzyme thymidylate synthase, thereby interfering with DNA synthesis and inhibiting cancer cell proliferation.
Antimetabolites can be classified into several subcategories based on their mechanism of action and chemical structure. These include purine and pyrimidine analogs, folic acid antagonists, and pyrimidine synthesis inhibitors. Examples of antimetabolites in these subcategories include azathioprine, cytarabine, and gemcitabine.
Despite their effectiveness, antimetabolites can exhibit certain side effects due to their interference with normal cellular processes. These side effects may include gastrointestinal disturbances, myelosuppression (reduced production of blood cells), and hepatotoxicity.
In conclusion, antimetabolites are a vital category of pharmaceutical APIs used in the treatment of various diseases, especially cancer. By mimicking natural metabolites and disrupting crucial cellular processes, these compounds effectively inhibit cancer cell growth and proliferation. However, their usage should be carefully monitored due to potential side effects.
Capecitabine manufacturers | traders | suppliers
We have 28 companies offering Capecitabine from 6 different countries.
Get in contact with the supplier of your choice:
- Shilpa Medicare Ltd from India
- Avanscure Lifesciences Pvt Ltd from India
- SENOVA Technology Co., Ltd. from China
- TIEFENBACHER API + Ingredients from Germany
- Shandong Boyuan from China
- Euticals from Italy
- Excella from Germany
- Laurus Labs from India
- Shanghai Jinhe Bio-Pharma from China
- Acebright Pharma from India
- Intas Pharma from United Kingdom
- Zhejiang Hisun Pharma from China
- Fareva from France
- Socosur from France
- Mac Chem Products from India
- Reliance Life Sciences from India
- Qilu Tianhe from China
- Signa from Mexico
- Adley Formulations from India
- Mylan from India
- Sun Pharma from India
- Dr. Reddy's from India
- Shaoxing Hantai Pharma from China
- Divis Labs. from India
- MSN Labs. from India
- Cipla from India
- Granules India from India
- Hetero Labs from India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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