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Cytarabine
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Distributor
Produced in:
Established in: 2011
MOQ: 1 kg
Employees: 10+
Fast Response and Good Communication
Willingness To Start From Small
Flexible Payment Terms
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Distributor
Produced in:
Established in: 1987
MOQ: 1 kg
Employees: 50+
ISO 9001:2015 & SGS audited supplier
One-stop CDMO Solutions for APl and Key intermediates
Specialized in APIs & Pharmaceutical Intermediates for 37 years
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Producer
Produced in:
Established in: 2012
MOQ: 1 kg
Employees: 50+
Diverse portfolio of APIs and Nutra products
Focus on Hormones Oncology and Peptides with the highest quality
Leading manufacturer of ALpha Lipoic Acid
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Looking for Cytarabine API 147-94-4?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Cytarabine. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Cytarabine
- Synonyms:
- Ara-C , Arabinofuranosyl Cytidine , Citarabina , Cytarabine , Cytarabinum , Cytosine arabinoside , Cytosine-1-beta-D-arabinofuranoside , Cytosine-beta-D-arabinofuranoside
- Cas Number:
- 147-94-4
- DrugBank number:
- DB00987
- Unique Ingredient Identifier:
- 04079A1RDZ
About Cytarabine
Here is a short description about Cytarabine. A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties.
You can find more info about this product by clicking on the DB ID above.
Cytarabine is a type of Antimetabolites
Antimetabolites are a prominent category of pharmaceutical active pharmaceutical ingredients (APIs) utilized in the treatment of various diseases, particularly cancer. These compounds are structurally similar to naturally occurring metabolites essential for cellular processes such as DNA and RNA synthesis. By mimicking these metabolites, antimetabolites interfere with the normal functioning of cellular pathways, leading to inhibition of cancer cell growth and proliferation.
One of the widely used antimetabolites is methotrexate, a folic acid antagonist that inhibits the enzyme dihydrofolate reductase, disrupting the production of DNA and RNA. This disruption impedes the growth of rapidly dividing cancer cells. Another common antimetabolite is 5-fluorouracil (5-FU), which inhibits the enzyme thymidylate synthase, thereby interfering with DNA synthesis and inhibiting cancer cell proliferation.
Antimetabolites can be classified into several subcategories based on their mechanism of action and chemical structure. These include purine and pyrimidine analogs, folic acid antagonists, and pyrimidine synthesis inhibitors. Examples of antimetabolites in these subcategories include azathioprine, cytarabine, and gemcitabine.
Despite their effectiveness, antimetabolites can exhibit certain side effects due to their interference with normal cellular processes. These side effects may include gastrointestinal disturbances, myelosuppression (reduced production of blood cells), and hepatotoxicity.
In conclusion, antimetabolites are a vital category of pharmaceutical APIs used in the treatment of various diseases, especially cancer. By mimicking natural metabolites and disrupting crucial cellular processes, these compounds effectively inhibit cancer cell growth and proliferation. However, their usage should be carefully monitored due to potential side effects.
Cytarabine manufacturers | traders | suppliers
We have 8 companies offering Cytarabine produced in 5 different countries.
Get in contact with the supplier of your choice:
- Shandong Octagon Chemicals Limited from China, product country of origin China
- Sinoway industrial Co.,Ltd from China, product country of origin China
- Asahi Kasei from Japan, product country of origin Japan
- Ferro Pfanstiehl Labs. from United States, product country of origin United States
- Zhejiang Hisun Pharma from China, product country of origin China
- Euticals from Italy, product country of origin Unknown
- Mac Chem Products from India, product country of origin India
- Avanscure Lifesciences Pvt Ltd from India, product country of origin India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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