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Raltitrexed
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Produced in:
Established in: 2008
MOQ: 1 kg
Employees: 300+
More than 150 patents based on independent intelligence
Expertise in anti-tumor, anti-diabetes and cardiovascular API and intermediates.
GMP facility with annual production capacity of 300M
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Looking for Raltitrexed API 112887-68-0?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Raltitrexed. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Raltitrexed
- Synonyms:
- Raltitrexed , Tomudex , ZD1694
- Cas Number:
- 112887-68-0
- DrugBank number:
- DB00293
- Unique Ingredient Identifier:
- FCB9EGG971
About Raltitrexed
Want to know what Raltitrexed is used for? Raltitrexed (brand name Tomudex) is a chemotherapy drug manufactured AstraZeneca Company, is an antimetabolite used in chemotherapy. It is an inhibitor of thymidylate synthase.
Ask the supplier for a certificate of analysis to find out more about the quality of Raltitrexed.
Raltitrexed is a type of Antimetabolites
Antimetabolites are a prominent category of pharmaceutical active pharmaceutical ingredients (APIs) utilized in the treatment of various diseases, particularly cancer. These compounds are structurally similar to naturally occurring metabolites essential for cellular processes such as DNA and RNA synthesis. By mimicking these metabolites, antimetabolites interfere with the normal functioning of cellular pathways, leading to inhibition of cancer cell growth and proliferation.
One of the widely used antimetabolites is methotrexate, a folic acid antagonist that inhibits the enzyme dihydrofolate reductase, disrupting the production of DNA and RNA. This disruption impedes the growth of rapidly dividing cancer cells. Another common antimetabolite is 5-fluorouracil (5-FU), which inhibits the enzyme thymidylate synthase, thereby interfering with DNA synthesis and inhibiting cancer cell proliferation.
Antimetabolites can be classified into several subcategories based on their mechanism of action and chemical structure. These include purine and pyrimidine analogs, folic acid antagonists, and pyrimidine synthesis inhibitors. Examples of antimetabolites in these subcategories include azathioprine, cytarabine, and gemcitabine.
Despite their effectiveness, antimetabolites can exhibit certain side effects due to their interference with normal cellular processes. These side effects may include gastrointestinal disturbances, myelosuppression (reduced production of blood cells), and hepatotoxicity.
In conclusion, antimetabolites are a vital category of pharmaceutical APIs used in the treatment of various diseases, especially cancer. By mimicking natural metabolites and disrupting crucial cellular processes, these compounds effectively inhibit cancer cell growth and proliferation. However, their usage should be carefully monitored due to potential side effects.
Raltitrexed manufacturers | traders | suppliers
We have 2 companies offering Raltitrexed produced in 2 different countries.
Get in contact with the supplier of your choice:
- Tianjin Pharmacn Medical Technology Co., ltd from China, product country of origin China
- Heraeus from Germany, product country of origin Germany
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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