Estramustine phosphate API Manufacturers

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Looking for Estramustine phosphate API 4891-15-0?

Description:
Here you will find a list of producers, manufacturers and distributors of Estramustine phosphate. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Estramustine phosphate 
Synonyms:
Estramustine 17-(dihydrogen phosphate)  
Cas Number:
4891-15-0 
DrugBank number:
DB14674 
Unique Ingredient Identifier:
MUZ9585Y7B

General Description:

Estramustine phosphate, identified by CAS number 4891-15-0, is a notable compound with significant therapeutic applications. A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.

Categories:

Estramustine phosphate is categorized under the following therapeutic classes: Alkylating Drugs, Antineoplastic Agents, Antineoplastic Agents, Alkylating, Antineoplastic Agents, Hormonal, Estranes, Estrenes, Fused-Ring Compounds, Hydrocarbons, Halogenated, Mustard Compounds, Nitrogen Mustard Compounds, Noxae, Steroids, Toxic Actions. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.

Estramustine phosphate is a type of Antineoplastics


Antineoplastics are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) primarily used in the treatment of cancer. These powerful substances inhibit or destroy the growth of cancer cells, thus impeding the progression of malignancies.

Antineoplastics exert their therapeutic effects through various mechanisms. Some APIs interfere with DNA replication, inhibiting the division and proliferation of cancer cells. Others target specific proteins or enzymes involved in tumor growth, effectively blocking their function. Additionally, certain antineoplastic agents induce programmed cell death, known as apoptosis, in cancer cells.

These APIs find application in a wide range of cancer treatments, including chemotherapy, targeted therapy, immunotherapy, and hormone therapy. They are often administered in combination with other drugs to optimize therapeutic outcomes and minimize drug resistance.

Antineoplastics are typically synthesized through complex chemical processes, ensuring high purity and potency. Stringent quality control measures are implemented throughout manufacturing to meet regulatory standards and ensure patient safety.

Although antineoplastics offer significant benefits in treating cancer, they can also cause adverse effects due to their cytotoxic nature. Common side effects include bone marrow suppression, gastrointestinal disturbances, hair loss, and immune system suppression. Close monitoring and supportive care are essential to manage these side effects effectively.

In conclusion, antineoplastics are a vital category of pharmaceutical APIs used in the treatment of cancer. Through their diverse mechanisms of action, these compounds play a critical role in combating malignancies and improving patient outcomes.