Find, compare & contact
Bemotrizinol
API Manufacturers & Suppliers
Join our notification list by following this page.
Click the button below to find out more
Click the button below to switch over to the contract services area of Pharmaoffer.
Looking for Bemotrizinol API 187393-00-6?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Bemotrizinol. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Bemotrizinol
- Synonyms:
- BEMT
- Cas Number:
- 187393-00-6
- DrugBank number:
- DB11206
- Unique Ingredient Identifier:
- PWZ1720CBH
General Description:
Bemotrizinol, identified by CAS number 187393-00-6, is a notable compound with significant therapeutic applications. Bemotrizinol, or bis-ethylhexyloxyphenol methoxyphenyl triazine, is an organic UV filter found in over-the-counter sunscreen products. It primarily absorbs UV-A rays. Compared to older broad-spectrum chemical agents, bemotrizinol is more more fat soluble (oil soluble in cosmetic oils) to aid in efficacy and broad-spectrum activity . It is claimed to be photostable, which increases its onset of action and its efficiency in providing protection against UV-rays upon topical application . Bemotrizinol is commonly marketed as Tinosorb S and Escalol S.
Indications:
This drug is primarily indicated for: Indicated as an active sunscreen agent. Its use in specific medical scenarios underscores its importance in the therapeutic landscape.
Metabolism:
Bemotrizinol undergoes metabolic processing primarily in: No pharmacokinetic data available. This metabolic pathway ensures efficient processing of the drug, helping to minimize potential toxicity and side effects.
Absorption:
The absorption characteristics of Bemotrizinol are crucial for its therapeutic efficacy: No pharmacokinetic data available. The drug's ability to rapidly penetrate into cells ensures quick onset of action.
Half-life:
The half-life of Bemotrizinol is an important consideration for its dosing schedule: No pharmacokinetic data available. This determines the duration of action and helps in formulating effective dosing regimens.
Protein Binding:
Bemotrizinol exhibits a strong affinity for binding with plasma proteins: No pharmacokinetic data available. This property plays a key role in the drug's pharmacokinetics and distribution within the body.
Route of Elimination:
The elimination of Bemotrizinol from the body primarily occurs through: No pharmacokinetic data available. Understanding this pathway is essential for assessing potential drug accumulation and toxicity risks.
Volume of Distribution:
Bemotrizinol is distributed throughout the body with a volume of distribution of: No pharmacokinetic data available. This metric indicates how extensively the drug permeates into body tissues.
Clearance:
The clearance rate of Bemotrizinol is a critical factor in determining its safe and effective dosage: No pharmacokinetic data available. It reflects the efficiency with which the drug is removed from the systemic circulation.
Pharmacodynamics:
Bemotrizinol exerts its therapeutic effects through: Findings from an immature rat uterotrophic competitive binding assay suggest that bemotrizinol does not display significant binding affinities towards estrogen and androgen receptors _in vitro_, thus lacking intrinsic estrogenic, antiestrogenic, androgenic and antiandrogenic activity . Bemotrizinol minimizes erythema and provides excellent anti-aging effects as well as protectant effects on the skin's antioxidant defense system . In a comparative study of individuals with a history of polymorphic light eruption (PLE) undergoing photoprovocation, treatment of bemotrinizol was effective in preventing the development of PLE . The drug's ability to modulate various physiological processes underscores its efficacy in treating specific conditions.
Mechanism of Action:
Bemotrizinol functions by: By absorbing UV-A and UVB rays ranging from 280 to 400nm, bemotrizinol serves to prevent the formation of free radicals induced by UV radiation . This mechanism highlights the drug's role in inhibiting or promoting specific biological pathways, contributing to its therapeutic effects.
Toxicity:
Categories:
Bemotrizinol is categorized under the following therapeutic classes: Benzene Derivatives, Sunscreen Agents. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Experimental Properties:
Further physical and chemical characteristics of Bemotrizinol include:
- Water Solubility: Insoluble
- Melting Point: 80.4
- Boiling Point: >400
Bemotrizinol is a type of Antioxidants
Antioxidants are a vital category of pharmaceutical Active Pharmaceutical Ingredients (APIs) that play a crucial role in preventing oxidative damage and promoting overall health. Oxidative stress occurs when there is an imbalance between the production of reactive oxygen species (ROS) and the body's antioxidant defense mechanisms.
Antioxidants function by neutralizing ROS and minimizing the potential harm they can cause to cells and tissues. This category includes a diverse range of compounds, such as vitamins (e.
g.
, vitamin C, vitamin E), minerals (e.
g.
, selenium, zinc), and phytochemicals (e.
g.
, polyphenols, flavonoids). These antioxidants can be obtained from natural sources like fruits, vegetables, and herbs, or they can be synthesized in laboratories for pharmaceutical use.
The role of antioxidants in the prevention and treatment of various diseases has been extensively studied. They have demonstrated the ability to reduce the risk of chronic diseases like cardiovascular disorders, cancer, and neurodegenerative conditions. Moreover, antioxidants exhibit anti-inflammatory properties, enhance immune function, and protect against age-related damage.
In the pharmaceutical industry, antioxidants are widely utilized as key ingredients in the formulation of drugs, dietary supplements, and cosmetic products. They contribute to the stability and shelf life of pharmaceutical preparations by preventing oxidative degradation. Antioxidant APIs are manufactured with strict quality control measures to ensure purity, efficacy, and safety.
In conclusion, antioxidants are essential pharmaceutical APIs that provide numerous health benefits. Their ability to counteract oxidative stress and protect cells from damage makes them a valuable component in the prevention and treatment of various diseases. The pharmaceutical industry relies on these antioxidants to enhance the quality and efficacy of their products, making them indispensable in the field of healthcare.
