Letrozole API Manufacturers

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Located in:

India

Produced in:

India

Established in: 1989

MOQ: -

Employees: 5000+

6 production facilities approved by USFDA, AGES-Austria, PMDA, WHO

R&D Centers with capabilities of ANDAs, DMFs and NDDS

462+ patents filed for drug substances and polymorphs

  • CoA

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  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • CEP

  • WC

  • GMP

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  • BSE/TSE

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Replies quickly

TOP RANKING

Located in:

Iran

Producer

Produced in:

Iran

Established in: 1956

MOQ: 1 kg

Employees: 200+

Expertise in Low Volume, High Value (LVHV) APIs

Technical knowledge for high-tech API production

therapeutic production sites with GMP compliance

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  • DMF

  • + 0

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Produced in:

China

Established in: 2011

MOQ: 1 g

Employees: 10+

Fast Response and Good Communication

Willingness To Start From Small

Flexible Payment Terms

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  • DMF

  • + 0

All certificates

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Replies can take a few days

Located in:

China

Passed ISO9001:2015 and SGS audit

Provide one-stop CDMO service from R&D to production

Certifications: ISO9001: 2015, HALAL Certificate, Kosher Certification

  • CoA

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  • DMF

  • + 0

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Distributor

Produced in:

World

Established in: 2005

MOQ: -

Employees: 200+

Portfolio of over 2,000 APIs

Precise quality control

End-to-end global regulatory support

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  • CEP

  • FDA

  • DMF

  • + 0

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  • DMF

  • CEP

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  • BSE/TSE

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Located in:

China

Engaged in the production of small molecule chemical drug APIs and preparations

Provide CDMO services for high-activity anti-tumor characteristic APIs

153-acre API and preparation production base

  • CoA

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  • DMF

  • + 0

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  • coa

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Located in:

China
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  • DMF

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  • DMF

  • CoA

  • WC

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Replies slower than most

Located in:

India

Producer

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  • DMF

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  • GMP

  • WC

  • DMF

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Replies slower than most

Located in:

China
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Replies slower than most

Producer

Produced in:

Unknown

Established in: 1944

MOQ: -

Employees: 4,000

14 international API plant sites

Portfolio of 350+ APIs

Teva is among the world’s largest generic drug/API manufacturers

  • CoA

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  • FDA

  • DMF

  • + 0

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  • DMF

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Located in:

China
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Replies slower than most

Located in:

Iceland
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  • DMF

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Replies slower than most

Located in:

India
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Replies slower than most

Located in:

United States

Producer

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  • DMF

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Located in:

India
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Located in:

India
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Located in:

India
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Replies slower than most

Located in:

France

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Replies slower than most

Located in:

India
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Replies slower than most

Located in:

India

Producer

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Located in:

India

Producer

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  • DMF

  • + 0

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Located in:

India

Producer

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  • FDA

  • DMF

  • + 0

All certificates

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Located in:

India

Producer

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HIGHLIGHTED

Located in:

United Kingdom
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  • FDA

  • DMF

  • + 0

All certificates

  • CoA

  • WC

  • MSDS

  • BSE/TSE

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  • EDMF/ASMF

  • JDMF

  • KDMF

  • GMP

  • ISO9001

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Looking for Letrozole API 112809-51-5?

Description:
Here you will find a list of producers, manufacturers and traders of Letrozole. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Letrozole 
Synonyms:
Femara , Letrozol , Letrozole  
Cas Number:
112809-51-5 
DrugBank number:
DB01006 
Unique Ingredient Identifier:
7LKK855W8I

About Letrozole

What can you use it for? Letrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990, It is a third generation aromatase inhibitor like exemestane and anastrozole, meaning it does not significantly affect cortisol, aldosterone, and thyroxine. Letrozole was granted FDA approval on 25 July 1997.

Do you want to buy this product? Send an inquiry to the listed suppliers that meets your quality requirements

Letrozole is a type of Aromatase inhibitors


Aromatase inhibitors (AIs) are a subcategory of pharmaceutical active pharmaceutical ingredients (APIs) commonly used in the treatment of hormone-sensitive conditions, including breast cancer and endometriosis. These compounds work by blocking the enzyme aromatase, which is responsible for the conversion of androgens into estrogens in peripheral tissues.

AIs are classified into two main types: steroidal and non-steroidal inhibitors. Steroidal AIs, such as exemestane, bind irreversibly to aromatase, while non-steroidal AIs, such as anastrozole and letrozole, inhibit aromatase activity reversibly. Both types effectively reduce estrogen levels, which is beneficial in hormone-driven cancers where estrogen promotes tumor growth.

The use of AIs in breast cancer treatment has significantly improved patient outcomes, particularly in postmenopausal women. By suppressing estrogen production, AIs prevent estrogen from fueling the growth of estrogen receptor-positive breast cancer cells. They are often prescribed as adjuvant therapy after surgery or as a first-line treatment for metastatic breast cancer.

Apart from their application in breast cancer, AIs have also shown efficacy in managing endometriosis, a painful condition where endometrial tissue grows outside the uterus. By reducing estrogen levels, AIs help alleviate symptoms and inhibit the growth of endometrial lesions.

Overall, aromatase inhibitors are vital components of modern pharmaceutical therapies targeting hormone-related diseases. Their ability to modulate estrogen levels through enzymatic inhibition has revolutionized the treatment landscape for breast cancer and endometriosis, improving patient prognosis and quality of life.


Letrozole (Aromatase inhibitors), classified under Hormonal Agents


Hormonal agents are a prominent category of pharmaceutical active pharmaceutical ingredients (APIs) widely used in the medical field. These substances play a crucial role in regulating and modulating hormonal functions within the body. Hormonal agents are designed to mimic or manipulate the effects of naturally occurring hormones, allowing healthcare professionals to treat various endocrine disorders and hormonal imbalances.

Hormonal agents are commonly employed in the treatment of conditions such as hypothyroidism, hyperthyroidism, diabetes, and hormonal cancers. These APIs work by interacting with specific hormone receptors, either by stimulating or inhibiting their activity, to restore the balance of hormones in the body. They can be administered orally, intravenously, or through other routes depending on the specific medication and patient needs.

Pharmaceutical companies employ rigorous manufacturing processes and quality control measures to ensure the purity, potency, and safety of hormonal agent APIs. These APIs are synthesized using chemical or biotechnological methods, often starting from natural hormone sources or through recombinant DNA technology. Stringent regulatory guidelines are in place to guarantee the efficacy and safety of hormonal agent APIs, ensuring that patients receive high-quality medications.

As the demand for hormone-related therapies continues to grow, ongoing research and development efforts focus on enhancing the effectiveness and reducing the side effects of hormonal agent APIs. This includes the exploration of novel delivery systems, advanced formulations, and targeted drug delivery methods. By continuously advancing our understanding and capabilities in hormonal agents, the medical community can improve patient outcomes and quality of life for individuals with hormonal disorders.



Letrozole manufacturers | traders | suppliers

We have 24 companies offering Letrozole produced in 7 different countries.

Get in contact with the supplier of your choice:

  • Shilpa Medicare Ltd from India, product country of origin India
  • Tofigh Daru from Iran, product country of origin Iran
  • Shandong Octagon Chemicals Limited from China, product country of origin China
  • Sinoway industrial Co.,Ltd from China, product country of origin China
  • LGM Pharma from United States, product country of origin World
  • Sichuan Elixir Pharmaceutical Co., Ltd from China, product country of origin China
  • Zhejiang Hisun Pharma from China, product country of origin China
  • USV from India, product country of origin India
  • Fujian South Pharma from China, product country of origin China
  • Teva API from Israel, product country of origin Unknown
  • Jiangsu Hengrui from China, product country of origin China
  • Actavis Group from Iceland, product country of origin Unknown
  • Natco Pharma from India, product country of origin India
  • ALCAMI from United States, product country of origin United States
  • Mac Chem Products from India, product country of origin India
  • Fresenius Kabi Onc. from India, product country of origin India
  • Ind-Swift Labs. from India, product country of origin India
  • Finorga from France, product country of origin France
  • Humble Healthcaare from India, product country of origin India
  • Cipla from India, product country of origin India
  • Mylan from India, product country of origin India
  • Hetero Labs from India, product country of origin India
  • Sun Pharma from India, product country of origin India
  • Health Options Europe from United Kingdom, product country of origin Iran

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