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Looking for Atomoxetine 83015-26-3?
More information about this product: Atomoxetine is a selective norepinephrine (NE) reuptake inhibitor used for the treatment of attention deficit hyperactivity disorder (ADHD). Also known as the marketed product Strattera, atomoxetine is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve developmentally inappropriate symptoms associated with ADHD including distractibility, short attention span, hyperactivity, emotional lability, and impulsivity. Although the underlying pathophysiology that causes ADHD remains unclear, evidence suggests that dysregulation in noradrenergic and dopaminergic pathways plays a critical role in suboptimal executive functioning within prefrontal regions of the brain, which are involved in attention and memory. Atomoxetine has been shown to specifically increase NA and DA within the prefrontal cortex, but not in the nucleus accumbens (NA) or striatum.
This is beneficial in the treatment of ADHD as DA activation in the subcortical NA and striatum is associated with many stimulant-associated side effects and an increase in abuse potential, which is a limiting factor associated with the use of stimulant medications such as Methylphenidate, Dextroamphetamine, and Lisdexamfetamine. Use of non-stimulant medications such as atomoxetine is therefore thought to offer a clinical advantage over the use of traditional medications for the management of ADHD. More recently, positron emission tomography (PET) imaging studies in rhesus monkeys have shown that atomoxetine also binds to the serotonin transporter (SERT) and blocks the N-methyl-d-aspartate (NMDA) receptor indicating a role for the glutamatergic system in the pathophysiology of ADHD.
Check who is selling Atomoxetine in the overview above.
Atomoxetine manufacturers | traders | suppliers
We have 17 companies offering Atomoxetine from 4 different countries.
Get in contact with the supplier of your choice:
- Shandong Octagon Chemicals Limited from China
- TIEFENBACHER API + Ingredients from Germany
- ZCL Chemicals from India
- SCI Pharmtech from Taiwan
- Aurobindo from India
- Mylan from India
- Dr. Reddy's from India
- Cadila Pharma from India
- R. L. Fine Chem from India
- Hetero Labs from India
- Sun Pharma from India
- Macleods Pharma from India
- Teva API from Israel
- MSN Organics from India
- Sharon Bio-Medicine from India
- Cadila Healthcare from India
- Unichem Labs. from India
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