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Avibactam
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Country of origin
Produced in:
Established in: 2004
MOQ: 1 kg
Employees: 3000
NO.2 Huangyang Road，
Yubei District, Chongqing
401120, P.R.China
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Producer
Produced in:
Established in: 2011
MOQ: 1 g
Employees: 10+
Fast Response and Good Communication
Willingness To Start From Small
Flexible Payment Terms
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Producer
Produced in:
Established in: 2024
MOQ: -
Employees: 50
Expertise in Complex API and NCE Process Development
Precision in Critical Impurities Preparation and Isolation
Agility in Scale-Up with Competitive Lead Times
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Looking for Avibactam API 1192500-31-4?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Avibactam. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Avibactam
- Synonyms:
- Avibactam Sodium
- Cas Number:
- 1192500-31-4
- DrugBank number:
- DB09060
- Unique Ingredient Identifier:
- 7352665165
About Avibactam
Here you will find more information about Avibactam. Avibactam is a non-β-lactam β-lactamase inhibitor that is available in combination with ceftazidime (Avycaz). This combination was approved by the FDA on February 25, 2015 for the treatment of complicated intra-abdominal infections in combination with metronidazole, and the treatment of complicated urinary tract infections, including pyelonephritis caused by antibiotic resistant-pathogens, including those caused by multi-drug resistant gram-negative bacterial pathogens. As there is limited clinical safety and efficacy data, Avycaz should be reserved for patients over 18 years old who have limited or not alternative treatment options.
You can ask the supplier for more technical information about the product.
Avibactam is a type of Beta-lactamase inhibitors
Beta-lactamase inhibitors are a crucial subcategory of pharmaceutical active pharmaceutical ingredients (APIs) that play a significant role in combating antibiotic resistance. These inhibitors are compounds specifically designed to enhance the effectiveness of beta-lactam antibiotics, which are widely used to treat bacterial infections. By inhibiting beta-lactamase enzymes, which are produced by bacteria to neutralize the activity of beta-lactam antibiotics, beta-lactamase inhibitors help restore the efficacy of these antibiotics.
The mechanism of action of beta-lactamase inhibitors involves binding to beta-lactamase enzymes, preventing them from inactivating beta-lactam antibiotics. This allows the antibiotics to effectively target and eliminate bacteria that would otherwise be resistant to their activity. By combining beta-lactamase inhibitors with beta-lactam antibiotics, healthcare professionals can overcome antibiotic resistance, expanding the range of infections that can be effectively treated.
Some commonly used beta-lactamase inhibitors include clavulanic acid, sulbactam, and tazobactam. These inhibitors are often formulated in combination with beta-lactam antibiotics, such as penicillins and cephalosporins, to create powerful therapeutic agents.
The development of beta-lactamase inhibitors is a critical strategy in the fight against antibiotic resistance, as it helps to extend the lifespan of existing antibiotics. By leveraging these inhibitors, healthcare providers can continue to use beta-lactam antibiotics effectively and combat infections caused by drug-resistant bacteria. Ongoing research and development efforts in this subcategory of pharmaceutical APIs are aimed at improving the efficacy and safety profiles of beta-lactamase inhibitors, thereby addressing the global challenge of antibiotic resistance.
Avibactam (Beta-lactamase inhibitors), classified under Antibacterials
Antibacterials, a category of pharmaceutical active pharmaceutical ingredients (APIs), play a crucial role in combating bacterial infections. These APIs are chemical compounds that target and inhibit the growth or kill bacteria, helping to eliminate harmful bacterial pathogens from the body.
Antibacterials are essential for the treatment of various bacterial infections, including respiratory tract infections, urinary tract infections, skin and soft tissue infections, and more. They are commonly prescribed by healthcare professionals to combat both mild and severe bacterial infections.
Within the category of antibacterials, there are different classes and subclasses of APIs, each with distinct mechanisms of action and target bacteria. Some commonly used antibacterials include penicillins, cephalosporins, tetracyclines, macrolides, and fluoroquinolones. These APIs work by interfering with various aspects of bacterial cellular processes, such as cell wall synthesis, protein synthesis, DNA replication, or enzyme activity.
The development and production of antibacterial APIs require stringent quality control measures to ensure their safety, efficacy, and purity. Pharmaceutical manufacturers must adhere to Good Manufacturing Practices (GMP) and follow rigorous testing protocols to guarantee the quality and consistency of these APIs.
As bacterial resistance to antibiotics continues to be a significant concern, ongoing research and development efforts aim to discover and develop new antibacterial APIs. The evolution of antibacterials plays a crucial role in combating emerging bacterial strains and ensuring effective treatment options for infectious diseases.
In summary, antibacterials are a vital category of pharmaceutical APIs used to treat bacterial infections. They are designed to inhibit or kill bacteria, and their development requires strict adherence to quality control standards. By continually advancing research in this field, scientists and pharmaceutical companies can contribute to the ongoing battle against bacterial infections.
Avibactam manufacturers | traders | suppliers
We have 3 companies offering Avibactam produced in 2 different countries.
Get in contact with the supplier of your choice:
- Fuan Pharmaceutical (Group) Co., LTD. from China, product country of origin China
- Shandong Octagon Chemicals Limited from China, product country of origin China
- ARLIVI Healthcare from India, product country of origin India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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