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Tacrolimus
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Distributor
Produced in:
Established in: 1987
MOQ: 1 kg
Employees: 50+
ISO 9001:2015 & SGS audited supplier
One-stop CDMO Solutions for APl and Key intermediates
Specialized in APIs & Pharmaceutical Intermediates for 37 years
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Producer
Produced in:
Established in: 2013
MOQ: 1 kg
Employees: 25+
ISO9001 certified
Drug R&D center (in Hangzhou)
From lab scale (mg/g) to commercial scale (kgs/tons)
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Producer
Produced in:
Established in: 2005
MOQ: 10 g
Employees: 85
Strict quality control
15 years of experience in API production
Provide OEM & ODM service
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Producer
Produced in:
Established in: 2019
MOQ: 1 g
Employees: 10+
Focused on pharmaceutical industry
Reasonable price for the customers
Full service from R&D stage to commercial stage
+ 0
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Producer
Produced in:
Established in: 2011
MOQ: 100 g
Employees: 10+
Fast Response and Good Communication
Willingness To Start From Small
Flexible Payment Terms
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Distributor
Produced in:
Established in: 1968
MOQ: 25 g
Employees: 50+
Warehouse stock of nearly all APIs
GMP, GDP and ISO certified
Customisable (small-sized) packages
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Producer
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Producer
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Distributor
Produced in:
Established in: 1963
MOQ: -
Employees: 800+
World’s 1st exclusive API distributor
Portfolio of 600+ APIs
>250 clients in Europe
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Distributor
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Distributor
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Producer
Produced in:
Established in: 1944
MOQ: -
Employees: 4,000
14 international API plant sites
Portfolio of 350+ APIs
Teva is among the world’s largest generic drug/API manufacturers
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Producer
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Producer
Produced in:
Established in: 1995
MOQ: -
Employees: 10000
Fermentation technology Experts
Partnerships with 1200 pharma companies in 100+ countries
US FDA, EMA, COFEPRIES, ANVISA, PMDA accreditations
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Producer
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Producer
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Looking for Tacrolimus API 104987-11-3?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Tacrolimus. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Tacrolimus
- Synonyms:
- Anhydrous tacrolimus , Tacrolimus anhydrous , Tacrolimus , anhydrous
- Cas Number:
- 104987-11-3
- DrugBank number:
- DB00864
- Unique Ingredient Identifier:
- Y5L2157C4J
About Tacrolimus
Want to know more about Tacrolimus? Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis after bone marrow transplants, and the skin condition vitiligo. It was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. Tacrolimus is chemically known as a macrolide.
It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex. This FKBP12-FK506 complex inhibits calcineurin which inhibits T-lymphocyte signal transduction and IL-2 transcription.
Check who is selling Tacrolimus in the overview above.
Tacrolimus is a type of Calcineurin inhibitors
Calcineurin inhibitors are a vital subcategory of pharmaceutical Active Pharmaceutical Ingredients (APIs) widely used in the treatment of various medical conditions. These inhibitors work by suppressing the activity of calcineurin, an enzyme that plays a crucial role in the immune response.
The primary application of calcineurin inhibitors is in the field of immunosuppression, particularly in organ transplantation. These medications prevent the rejection of transplanted organs by inhibiting the production of cytokines, such as interleukin-2, which are responsible for triggering the immune response. By modulating the immune system, calcineurin inhibitors enable successful transplantation and enhance patient outcomes.
Furthermore, calcineurin inhibitors find utility in the treatment of autoimmune disorders, including psoriasis and rheumatoid arthritis. These medications help alleviate symptoms and reduce inflammation by interfering with the immune system's response.
The two most commonly used calcineurin inhibitors are cyclosporine and tacrolimus. These compounds exhibit high specificity and affinity for calcineurin, ensuring effective immunosuppression. Both drugs are available in various formulations, including oral capsules, injectables, and topical preparations, enabling healthcare professionals to tailor treatment to individual patient needs.
It is important to note that calcineurin inhibitors may have certain side effects, including nephrotoxicity, hypertension, and increased susceptibility to infections. Close monitoring of patients and appropriate dosage adjustments are crucial to maintaining the delicate balance between immune suppression and overall health.
In summary, calcineurin inhibitors represent a vital subcategory of pharmaceutical APIs used in immunosuppressive therapy for organ transplantation and autoimmune disorders. Their ability to modulate the immune response plays a crucial role in achieving successful patient outcomes.
Tacrolimus (Calcineurin inhibitors), classified under Dermatological Agents
Dermatological agents are a vital category of pharmaceutical active pharmaceutical ingredients (APIs) used in the formulation of various skincare and dermatology products. These APIs are specifically designed to target and treat skin conditions, offering effective solutions for a wide range of dermatological concerns.
Dermatological agents encompass a diverse array of compounds, including corticosteroids, antifungal agents, antibacterials, retinoids, and immunomodulators. Each API within this category possesses unique properties and mechanisms of action, enabling them to address specific skin-related issues.
Corticosteroids, for instance, are potent anti-inflammatory agents commonly used in the treatment of skin conditions like eczema, psoriasis, and dermatitis. Antifungal agents, on the other hand, combat fungal infections such as athlete's foot or ringworm. Antibacterials are effective against bacterial infections, while retinoids promote skin cell turnover and treat acne and photoaging. Immunomodulators regulate the immune response, providing relief from conditions like atopic dermatitis.
The development and application of dermatological APIs involve rigorous research, clinical trials, and regulatory compliance. These APIs are typically integrated into topical creams, ointments, gels, and lotions, ensuring targeted delivery to the affected areas of the skin.
Dermatological agents play a crucial role in the management and treatment of various skin disorders. By harnessing the therapeutic properties of these APIs, pharmaceutical companies can develop innovative skincare products that cater to the diverse needs of individuals seeking effective dermatological solutions.
Tacrolimus manufacturers | traders | suppliers
We have 19 companies offering Tacrolimus produced in 6 different countries.
Get in contact with the supplier of your choice:
- Sinoway industrial Co.,Ltd from China, product country of origin China
- Senova Technology Co., Ltd. from China, product country of origin China
- Xi'an Tian Guangyuan Biotech Co.,Ltd from China, product country of origin China
- Apino Pharma Co., Ltd. from China, product country of origin China
- Shandong Octagon Chemicals Limited from China, product country of origin China
- Duchefa Farma B.V. from Netherlands, product country of origin India
- CKD Bio from South Korea, product country of origin South Korea
- Astellas Pharma from Japan, product country of origin Japan
- TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
- Kromozome from India, product country of origin India
- Flavine from Germany, product country of origin Unknown
- Teva API from Israel, product country of origin Unknown
- Euticals from Italy, product country of origin Italy
- Biocon from India, product country of origin India
- Stilbene Biopharma from India, product country of origin India
- Fujian Kerui from China, product country of origin China
- Murli Krishna Pharma Pvt. Ltd from India, product country of origin India
- Shaoxing Hantai Pharma from China, product country of origin China
- Lek Pharma from Slovenia, product country of origin India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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