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Looking for Maraviroc API 376348-65-1?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Maraviroc. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Maraviroc
- Cas Number:
- 376348-65-1
- DrugBank number:
- DB04835
- Unique Ingredient Identifier:
- MD6P741W8A
About Maraviroc
Want to know more about Maraviroc? Maraviroc (brand-named Selzentry, or Celsentri outside the U.S.) is a chemokine receptor antagonist drug developed by the drug company Pfizer that is designed to act against HIV by interfering with the interaction between HIV and CCR5. It was originally labelled as UK-427857 during development but was assigned the Maraviroc name as it entered trials. It was approved for use by the FDA in August, 2007.
Do you want to buy this product? Send an inquiry to the listed suppliers that meets your quality requirements
Maraviroc is a type of CCR5 antagonists
CCR5 antagonists belong to the subcategory of pharmaceutical active pharmaceutical ingredients (APIs) that target the CCR5 receptor. These antagonists are designed to inhibit the activity of the CCR5 receptor, which plays a crucial role in various immune responses. CCR5 antagonists have gained significant attention in the field of HIV/AIDS treatment due to their ability to block the entry of HIV into host cells.
CCR5, short for CC chemokine receptor 5, is a cell surface receptor primarily found on immune cells, including T cells and macrophages. It acts as a co-receptor for HIV, facilitating viral entry and infection. By inhibiting the CCR5 receptor, antagonists prevent HIV from binding to and infecting host cells, thereby reducing viral replication and disease progression.
The development of CCR5 antagonists has revolutionized the treatment of HIV/AIDS. One well-known CCR5 antagonist is maraviroc, which has been approved by regulatory authorities for the treatment of HIV infection. Maraviroc specifically binds to the CCR5 receptor, blocking the interaction between HIV and the receptor.
CCR5 antagonists offer several advantages in HIV therapy, such as reduced side effects compared to traditional antiretroviral drugs. They are typically well-tolerated and have shown efficacy in both treatment-naive and treatment-experienced patients. Additionally, CCR5 antagonists may have potential applications in other diseases, including certain inflammatory conditions and cancers.
In conclusion, CCR5 antagonists are a promising class of pharmaceutical APIs that target the CCR5 receptor. Their ability to inhibit HIV entry into host cells has made them a valuable addition to the arsenal of antiretroviral therapies. Ongoing research aims to further explore their potential applications in various disease areas.
Maraviroc (CCR5 antagonists), classified under Anti-infective Agents
Anti-infective agents are a vital category of pharmaceutical active pharmaceutical ingredients (APIs) used in the treatment of various infectious diseases. These agents play a crucial role in combating bacterial, viral, fungal, and parasitic infections. The demand for effective anti-infective APIs has grown significantly due to the increasing prevalence of drug-resistant microorganisms.
Anti-infective APIs encompass a wide range of substances, including antibiotics, antivirals, antifungals, and antiparasitics. Antibiotics are particularly important in fighting bacterial infections and are further categorized into different classes based on their mode of action and target bacteria. Antivirals are designed to inhibit viral replication and are essential in the treatment of viral infections such as influenza and HIV. Antifungals combat fungal infections, while antiparasitics are used to eliminate parasites that cause diseases like malaria and helminthiasis.
The development and production of high-quality anti-infective APIs require stringent manufacturing processes and adherence to regulatory standards. Pharmaceutical companies invest heavily in research and development to discover new and more effective anti-infective agents. Additionally, ensuring the safety, efficacy, and stability of these APIs is of utmost importance.
The global market for anti-infective APIs is driven by factors such as the rising incidence of infectious diseases, the emergence of new and drug-resistant pathogens, and the growing demand for improved healthcare infrastructure. Continuous advancements in pharmaceutical technology and the development of innovative drug delivery systems further contribute to the expansion of this market.
In conclusion, anti-infective agents are a critical category of pharmaceutical APIs that play a pivotal role in treating infectious diseases. Their effectiveness in combating various types of infections makes them essential components in the arsenal of modern medicine.
Maraviroc manufacturers | traders | suppliers
We have 2 companies offering Maraviroc produced in 2 different countries.
Get in contact with the supplier of your choice:
- Cambrex from Italy, product country of origin United States
- Hetero Labs from India, product country of origin India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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