Pholcodine API Manufacturers
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Country of origin
Established in: 1997
Exports 25 products to 52 countries in 5 continents
21 active production lines of GMP standards
Specialized in Narcotic and Non-Narcotic APIs, FDFs and Intermediates
Established in: 1963
World’s 1st exclusive API distributor
Portfolio of 600+ APIs
>250 clients in Europe
Established in: 1941
Pilot plant & cGMP Kilolab
Human API & Veterinary API EU GMP
API and FDF production, API R&D & CDMO
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Looking for Pholcodine API 509-67-1?
- Here you will find a list of producers, manufacturers and traders of Pholcodine. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Pholcodine monohydrate
- Cas Number:
- DrugBank number:
- Unique Ingredient Identifier:
What makes Pholcodine unique? Pholcodine formula is 3-o-morpholinoethylmorphine and it is classified as an antitussive which is defined as an opioid cough suppressant. It belongs to the opioid family of compounds and it is widely used. Pholcodine activity is the suppression of unproductive cough and it also has a mild sedative effect with little or no analgesic effects. Pholcodine is not prescribed in the United States where it is classed as a Schedule I drug. It is categorized as Class B drug in the UK and officially taken out of the shelves in 2008. Pholcodine is not approved in Canada.
More information such as the structure, indication or toxicity is available on Drugbank, click the ID above.
Pholcodine is a type of Cough suppressants
Cough suppressants, a subcategory of pharmaceutical active pharmaceutical ingredients (APIs), are commonly used to alleviate coughing symptoms. These medications act on the central nervous system to reduce the urge to cough, providing temporary relief and improving patient comfort. Cough suppressants are widely employed in the treatment of various respiratory conditions, including colds, flu, bronchitis, and allergies.
The primary mechanism of action for cough suppressants involves targeting the cough reflex arc. This reflex arc comprises sensory nerve fibers in the respiratory tract that detect irritants, sending signals to the brainstem to initiate coughing. Cough suppressants work by suppressing this reflex at different points, depending on the specific drug.
One widely used class of cough suppressants is opioid derivatives, such as codeine and hydrocodone. These substances act by binding to opioid receptors in the brain, decreasing the sensitivity of the cough reflex. Another class includes non-opioid agents, such as dextromethorphan, which functions by affecting receptors in the brain called NMDA receptors.
Cough suppressants are available in various formulations, including oral syrups, tablets, and capsules. They are often combined with other active ingredients, such as expectorants or antihistamines, to provide a more comprehensive treatment approach.
While cough suppressants can provide symptomatic relief, it is crucial to use them under proper medical guidance. Certain individuals, such as those with respiratory conditions like chronic obstructive pulmonary disease (COPD) or asthma, may require cautious use or alternative treatment options due to potential side effects or drug interactions.
In conclusion, cough suppressants are an essential subcategory of pharmaceutical APIs utilized to manage coughing symptoms. These medications work by targeting the cough reflex arc in the central nervous system, providing temporary relief from coughing. Careful consideration should be given to appropriate usage and potential contraindications, ensuring safe and effective treatment.
Pholcodine (Cough suppressants), classified under Respiratory Tract Agents
Respiratory Tract Agents are a vital category of pharmaceutical APIs (Active Pharmaceutical Ingredients) designed to treat respiratory conditions and diseases. These agents are specifically formulated to target the respiratory system, which includes the lungs, airways, and nasal passages. They play a crucial role in managing various respiratory disorders, such as asthma, chronic obstructive pulmonary disease (COPD), and allergic rhinitis.
Respiratory Tract Agents encompass a wide range of medications, including bronchodilators, corticosteroids, antihistamines, and mucolytics. Bronchodilators are commonly used to relieve airway constriction and facilitate smooth breathing by relaxing the muscles in the airways. Corticosteroids help reduce inflammation in the respiratory system, alleviating symptoms and preventing exacerbations. Antihistamines work by blocking histamine receptors, thus mitigating allergic reactions that often impact the respiratory tract. Mucolytics aid in loosening and thinning mucus, making it easier to expel from the airways.
These APIs are developed through rigorous research and development processes, ensuring their efficacy, safety, and compliance with regulatory standards. Pharmaceutical manufacturers rely on advanced technologies and stringent quality control measures to produce high-quality Respiratory Tract Agents. These APIs are subsequently incorporated into various dosage forms, including inhalers, nasal sprays, nebulizers, and oral medications.
Respiratory Tract Agents are essential in the management of respiratory conditions, providing relief from symptoms, improving lung function, and enhancing the overall quality of life for patients. They are prescribed by healthcare professionals and often used in combination therapies to achieve optimal results. As respiratory disorders continue to affect a significant portion of the global population, the development and availability of effective Respiratory Tract Agents play a vital role in addressing these health challenges and improving patient outcomes.
Pholcodine manufacturers | traders | suppliers
We have 5 companies offering Pholcodine produced in 4 different countries.
Get in contact with the supplier of your choice:
- Temad Co. from Iran, product country of origin Iran
- TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
- Saneca Pharma from Slovakia, product country of origin Slovakia
- PCAS from France, product country of origin Unknown
- Macfarlan Smith from United Kingdom, product country of origin United Kingdom
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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