Elbasvir API Manufacturers
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Looking for Elbasvir API 1370468-36-2?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Elbasvir. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Elbasvir
- Cas Number:
- 1370468-36-2
- DrugBank number:
- DB11574
- Unique Ingredient Identifier:
- 632L571YDK
About Elbasvir
Here is a short description about Elbasvir. Elbasvir is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C, an infectious liver disease caused by infection with hepatitis C virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, affecting 72% of all chronic HCV patients. Treatment options for chronic hepatitis C have advanced significantly since 20 with the development of direct-acting antivirals (DAAs) such as elbasvir.
Elbasvir is an inhibitor of NS5A, a protein essential for viral replication and virion assembly.Synthesis The barrier to the development of resistance to NS5A inhibitors is lower than that of NS5B inhibitors, another class of DAAs. Substitutions at amino acid positions 28, 30, 31, or 93 are known to confer resistance to elbasvir. Despite this disadvantage elbasvir is still effective against HCV, particularly when paired with grazoprevir.
You can find more info about this product by clicking on the DB ID above.
