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Zinc gluconate
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Looking for Zinc gluconate API 4468-02-4?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Zinc gluconate. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Zinc gluconate
- Synonyms:
- Cas Number:
- 4468-02-4
- DrugBank number:
- DB11248
- Unique Ingredient Identifier:
- U6WSN5SQ1Z
General Description:
Zinc gluconate, identified by CAS number 4468-02-4, is a notable compound with significant therapeutic applications. Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA . It is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration of common colds and with decreased symptom severity. Although it has been nasally administered for treating the common cold, this route of administration has been associated with some cases of anosmia , , , . Studies show that zinc may be better absorbed in humans in the gluconate form , , however, results from other studies may vary. Interestingly, zinc supplementation has become a critical intervention for treating diarrheal episodes in children. Studies suggest that administration of zinc along with new low osmolarity oral rehydration solutions/salts (oral rehydration solution), may reduce both the duration and severity of diarrheal episodes for up to 12 weeks . More information about Zinc (in its natural form) is available at .
Indications:
This drug is primarily indicated for: Zinc gluconate is mainly indicated in conditions like zinc deficiency, and can also be administered in adjunctive therapy as an alternative drug of choice in diarrhea . Its use in specific medical scenarios underscores its importance in the therapeutic landscape.
Metabolism:
Zinc gluconate undergoes metabolic processing primarily in: Please refer to DrugBank entry. This metabolic pathway ensures efficient processing of the drug, helping to minimize potential toxicity and side effects.
Absorption:
The absorption characteristics of Zinc gluconate are crucial for its therapeutic efficacy: Please refer to DrugBank entry. The drug's ability to rapidly penetrate into cells ensures quick onset of action.
Half-life:
The half-life of Zinc gluconate is an important consideration for its dosing schedule: 280 days. This determines the duration of action and helps in formulating effective dosing regimens.
Protein Binding:
Zinc gluconate exhibits a strong affinity for binding with plasma proteins: Please refer to DrugBank entry. This property plays a key role in the drug's pharmacokinetics and distribution within the body.
Route of Elimination:
The elimination of Zinc gluconate from the body primarily occurs through: Feces and urine. Understanding this pathway is essential for assessing potential drug accumulation and toxicity risks.
Volume of Distribution:
Zinc gluconate is distributed throughout the body with a volume of distribution of: Stored primarily in skeletal muscle and bone . This metric indicates how extensively the drug permeates into body tissues.
Clearance:
The clearance rate of Zinc gluconate is a critical factor in determining its safe and effective dosage: Please refer to DrugBank entry. It reflects the efficiency with which the drug is removed from the systemic circulation.
Pharmacodynamics:
Zinc gluconate exerts its therapeutic effects through: Zinc is an important mineral found in almost every cell in the human body. It promotes the activity of about 100 enzymes. Zinc deficiency is often associated with an increased risk of infection. When they are used to treat the common cold, zinc supplements may interfere with rhinovirus cleavage or adhesion and may play a role in protecting plasma membranes from microbial toxins and complement . The drug's ability to modulate various physiological processes underscores its efficacy in treating specific conditions.
Mechanism of Action:
Zinc gluconate functions by: Although the mechanism of action is not completely known, zinc supplementation may be used to increase immunity against viruses or may interfere with the replication of certain viruses, such as the human papillomavirus (HPV) . This mechanism highlights the drug's role in inhibiting or promoting specific biological pathways, contributing to its therapeutic effects.
Toxicity:
Classification:
Zinc gluconate belongs to the class of organic compounds known as sugar acids and derivatives. These are compounds containing a saccharide unit which bears a carboxylic acid group, classified under the direct parent group Sugar acids and derivatives. This compound is a part of the Organic compounds, falling under the Organic oxygen compounds superclass, and categorized within the Organooxygen compounds class, specifically within the Carbohydrates and carbohydrate conjugates subclass.
Categories:
Zinc gluconate is categorized under the following therapeutic classes: Acids, Acyclic, Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use, Alimentary Tract and Metabolism, Carbohydrates, Hydroxy Acids, Metal cations, Metal divalent cations, Mineral Supplements, Sugar Acids, Vasoprotectives, Zinc Compounds. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Experimental Properties:
Further physical and chemical characteristics of Zinc gluconate include:
- Water Solubility: moderately soluble
Zinc gluconate is a type of Electrolytes
Electrolytes are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) that play a vital role in maintaining the balance of essential ions in the body. These ions include sodium, potassium, calcium, magnesium, and chloride, among others. Electrolytes are responsible for maintaining proper hydration, regulating nerve and muscle function, and supporting various physiological processes.
In the pharmaceutical industry, electrolytes are widely utilized in the formulation of oral rehydration solutions, intravenous fluids, and dialysis solutions. These medications are employed to treat conditions such as dehydration, electrolyte imbalances, and renal dysfunction.
The availability of high-quality electrolyte APIs is of utmost importance to ensure the efficacy and safety of these pharmaceutical products. Pharmaceutical manufacturers rely on reputable suppliers who adhere to stringent quality control measures and comply with Good Manufacturing Practices (GMP) to produce electrolyte APIs of consistent quality.
To meet regulatory requirements, electrolyte APIs undergo rigorous testing to confirm their identity, purity, and potency. This includes analysis using advanced techniques such as high-performance liquid chromatography (HPLC), mass spectrometry (MS), and atomic absorption spectroscopy (AAS).
In conclusion, electrolytes are a vital category of pharmaceutical APIs used to maintain the balance of essential ions in the body. They are extensively employed in various medications aimed at treating dehydration, electrolyte imbalances, and renal dysfunction. Pharmaceutical manufacturers prioritize the use of high-quality electrolyte APIs to ensure the safety and efficacy of their products, and adherence to stringent regulatory standards is crucial in their production and testing processes.
Zinc gluconate manufacturers | traders | suppliers
We have 1 companies offering Zinc gluconate produced in 1 different countries.
Get in contact with the supplier of your choice:
- Aurora Industry Co., Ltd from China, product country of origin China
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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