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Nadide
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Looking for Nadide API 53-84-9?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Nadide. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Nadide
- Synonyms:
- beta-Diphosphopyridine nucleotide , beta-NAD , beta-NAD+ , beta-Nicotinamide adenine dinucleotide , Codehydrase I , Codehydrogenase I , Coenzyme I , Cozymase I , Diphosphopyridine nucleotide , DPN , NAD , NAD+ , Nadida , Nadidum , Nicotinamide adenine dinucleotide , Nicotinamide dinucleotide , Nicotinamide-adenine dinucleotide , Nicotineamide adenine dinucleotide , Oxidized diphosphopyridine nucleotide , Pyridine, nucleotide diphosphate
- Cas Number:
- 53-84-9
- DrugBank number:
- DB14128
- Unique Ingredient Identifier:
- 0U46U6E8UK
General Description:
Nadide, identified by CAS number 53-84-9, is a notable compound with significant therapeutic applications. A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
Classification:
Nadide belongs to the class of organic compounds known as (5'->5')-dinucleotides. These are dinucleotides where the two bases are connected via a (5'->5')-phosphodiester linkage, classified under the direct parent group (5'->5')-dinucleotides. This compound is a part of the Organic compounds, falling under the Nucleosides, nucleotides, and analogues superclass, and categorized within the (5'->5')-dinucleotides class, specifically within the None subclass.
Categories:
Nadide is categorized under the following therapeutic classes: Adenine Nucleotides, Coenzymes, Enzymes and Coenzymes, Heterocyclic Compounds, Fused-Ring, Nucleic Acids, Nucleotides, and Nucleosides, Nucleotides, Purine Nucleotides, Purines, Ribonucleotides. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Nadide is a type of Enzyme Replacements/modifiers
Enzyme replacements/modifiers are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) utilized in the treatment of various enzyme-related disorders. Enzymes play a vital role in the normal functioning of the body by catalyzing specific biochemical reactions. However, in certain medical conditions, the body may lack or produce dysfunctional enzymes, leading to serious health complications.
Enzyme replacement therapy (ERT) involves administering exogenous enzymes to compensate for the enzyme deficiency in patients. These enzymes are typically derived from natural sources or produced using recombinant DNA technology. By introducing these enzymes into the body, they can effectively substitute the missing or defective enzymes, thereby restoring normal metabolic processes.
On the other hand, enzyme modifiers are API substances that regulate the activity of specific enzymes within the body. These modifiers can either enhance or inhibit the enzyme's function, depending on the therapeutic objective. By modulating enzyme activity, these APIs can restore the balance of enzymatic reactions, leading to improved physiological outcomes.
Enzyme replacements/modifiers have shown remarkable success in treating various genetic disorders, such as Gaucher disease, Fabry disease, and lysosomal storage disorders. Additionally, they have demonstrated potential in managing enzyme deficiencies associated with rare diseases and certain types of cancer.
The development and production of enzyme replacements/modifiers involve rigorous research, formulation optimization, and adherence to stringent quality control measures. Pharmaceutical companies invest substantial resources in developing these APIs to ensure their safety, efficacy, and compliance with regulatory standards.
Overall, enzyme replacements/modifiers represent a vital therapeutic category in modern medicine, offering hope and improved quality of life for patients with enzyme-related disorders.
