Nicotinamide adenine dinucleotide phosphate API Manufacturers

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Looking for Nicotinamide adenine dinucleotide phosphate API 53-59-8?

Description:
Here you will find a list of producers, manufacturers and distributors of Nicotinamide adenine dinucleotide phosphate. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Nicotinamide adenine dinucleotide phosphate 
Synonyms:
Codehydrase II , Codehydrogenase II , Coenzyme II , Triphosphopyridine nucleotide  
Cas Number:
53-59-8 
DrugBank number:
DB03461 
Unique Ingredient Identifier:
BY8P107XEP

General Description:

Nicotinamide adenine dinucleotide phosphate, identified by CAS number 53-59-8, is a notable compound with significant therapeutic applications. Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)

Classification:

Nicotinamide adenine dinucleotide phosphate belongs to the class of organic compounds known as (5'->5')-dinucleotides. These are dinucleotides where the two bases are connected via a (5'->5')-phosphodiester linkage, classified under the direct parent group (5'->5')-dinucleotides. This compound is a part of the Organic compounds, falling under the Nucleosides, nucleotides, and analogues superclass, and categorized within the (5'->5')-dinucleotides class, specifically within the None subclass.

Categories:

Nicotinamide adenine dinucleotide phosphate is categorized under the following therapeutic classes: Adenine Nucleotides, Coenzymes, Enzymes and Coenzymes, Heterocyclic Compounds, Fused-Ring, Nucleic Acids, Nucleotides, and Nucleosides, Nucleotides, Purine Nucleotides, Purines, Ribonucleotides. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.

Nicotinamide adenine dinucleotide phosphate is a type of Enzyme Replacements/modifiers


Enzyme replacements/modifiers are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) utilized in the treatment of various enzyme-related disorders. Enzymes play a vital role in the normal functioning of the body by catalyzing specific biochemical reactions. However, in certain medical conditions, the body may lack or produce dysfunctional enzymes, leading to serious health complications.

Enzyme replacement therapy (ERT) involves administering exogenous enzymes to compensate for the enzyme deficiency in patients. These enzymes are typically derived from natural sources or produced using recombinant DNA technology. By introducing these enzymes into the body, they can effectively substitute the missing or defective enzymes, thereby restoring normal metabolic processes.

On the other hand, enzyme modifiers are API substances that regulate the activity of specific enzymes within the body. These modifiers can either enhance or inhibit the enzyme's function, depending on the therapeutic objective. By modulating enzyme activity, these APIs can restore the balance of enzymatic reactions, leading to improved physiological outcomes.

Enzyme replacements/modifiers have shown remarkable success in treating various genetic disorders, such as Gaucher disease, Fabry disease, and lysosomal storage disorders. Additionally, they have demonstrated potential in managing enzyme deficiencies associated with rare diseases and certain types of cancer.

The development and production of enzyme replacements/modifiers involve rigorous research, formulation optimization, and adherence to stringent quality control measures. Pharmaceutical companies invest substantial resources in developing these APIs to ensure their safety, efficacy, and compliance with regulatory standards.

Overall, enzyme replacements/modifiers represent a vital therapeutic category in modern medicine, offering hope and improved quality of life for patients with enzyme-related disorders.